GO ID Total Under Over Change P-Value Term 15078 70 0 0 40 0 hydrogen ion transporter activity 15077 71 0 0 40 0 monovalent inorganic cation transporter activity 15075 145 0 0 47 0 ion transporter activity 15002 12 0 0 9 0 heme-copper terminal oxidase activity 46164 40 0 0 19 0 alcohol catabolism 46034 19 0 0 12 0 ATP metabolism 6818 46 0 0 25 0 hydrogen transport 6754 17 0 0 11 0 ATP biosynthesis 6753 17 0 0 11 0 nucleoside phosphate metabolism 6457 49 0 0 21 0 protein folding 6413 24 0 0 14 0 translational initiation 6412 265 0 0 130 0 protein biosynthesis 1584 171 0 0 2 0 rhodopsin-like receptor activity 6397 82 0 0 36 0 mRNA processing 6396 123 0 0 48 0 RNA processing 6371 57 0 0 30 0 mRNA splicing 6355 782 0 0 89 0 "regulation of transcription, DNA-dependent" 6351 836 0 0 100 0 "transcription, DNA-dependent" 6350 862 0 0 108 0 transcription 6164 37 0 0 18 0 purine nucleotide biosynthesis 6092 64 0 0 28 0 main pathways of carbohydrate metabolism 6091 109 0 0 38 0 energy pathways 6007 40 0 0 19 0 glucose catabolism 9987 3132 0 0 467 0 cellular process 9887 489 0 0 39 0 organogenesis 4930 240 0 0 4 0 G-protein coupled receptor activity 4888 476 0 0 23 0 transmembrane receptor activity 4872 733 0 0 59 0 receptor activity 4871 1135 0 0 91 0 signal transducer activity 9653 531 0 0 50 0 morphogenesis 9547 16 0 0 16 0 plastid ribosome 9536 26 0 0 19 0 plastid 9532 17 0 0 16 0 plastid stroma 9507 20 0 0 15 0 chloroplast 16676 12 0 0 9 0 "oxidoreductase activity, acting on heme group of donors, oxygen as acceptor" 16675 12 0 0 9 0 "oxidoreductase activity, acting on heme group of donors" 16651 27 0 0 16 0 "oxidoreductase activity, acting on NADH or NADPH" 16491 312 0 0 107 0 oxidoreductase activity 9260 36 0 0 18 0 ribonucleotide biosynthesis 9259 42 0 0 20 0 ribonucleotide metabolism 9206 25 0 0 14 0 purine ribonucleoside triphosphate biosynthesis 9205 27 0 0 15 0 purine ribonucleoside triphosphate metabolism 9201 25 0 0 14 0 ribonucleoside triphosphate biosynthesis 42625 58 0 0 24 0 "ATPase activity, coupled to transmembrane movement of ions" 9199 27 0 0 15 0 ribonucleoside triphosphate metabolism 9152 34 0 0 17 0 purine ribonucleotide biosynthesis 9150 40 0 0 19 0 purine ribonucleotide metabolism 9145 25 0 0 14 0 purine nucleoside triphosphate biosynthesis 9144 28 0 0 15 0 purine nucleoside triphosphate metabolism 16283 26 0 0 26 0 eukaryotic 48S initiation complex 16282 28 0 0 28 0 eukaryotic 43S pre-initiation complex 4299 16 0 0 11 0 proteasome endopeptidase activity 30529 207 0 0 122 0 ribonucleoprotein complex 30528 622 0 0 56 0 transcription regulator activity 16209 9 0 0 10 0 antioxidant activity 9059 266 0 0 131 0 macromolecule biosynthesis 9058 553 0 0 198 0 biosynthesis 4129 12 0 0 9 0 cytochrome c oxidase activity 16070 129 0 0 50 0 RNA metabolism 16052 44 0 0 20 0 carbohydrate catabolism 16043 541 0 0 150 0 cell organization and biogenesis 16021 1655 0 0 220 0 integral to membrane 16020 2124 0 0 322 0 membrane 42254 75 0 0 42 0 ribosome biogenesis and assembly 19866 87 0 0 34 0 inner membrane 30001 178 0 0 12 0 metal ion transport 19538 1194 0 0 296 0 protein metabolism 19320 40 0 0 19 0 hexose catabolism 7275 883 0 0 92 0 development 7268 103 0 0 4 0 synaptic transmission 7267 150 0 0 7 0 cell-cell signaling 45449 793 0 0 92 0 regulation of transcription 7186 354 0 0 17 0 G-protein coupled receptor protein signaling pathway 7166 582 0 0 42 0 cell surface receptor linked signal transduction 7165 1075 0 0 112 0 signal transduction 7154 1392 0 0 134 0 cell communication 19028 17 0 0 11 0 viral capsid 7046 70 0 0 40 0 ribosome biogenesis 19013 17 0 0 11 0 viral nucleocapsid 7028 396 0 0 118 0 cytoplasm organization and biogenesis 5887 384 0 0 30 0 integral to plasma membrane 5886 763 0 0 95 0 plasma membrane 5843 25 0 0 25 0 cytosolic small ribosomal subunit (sensu Eukarya) 5842 30 0 0 30 0 cytosolic large ribosomal subunit (sensu Eukarya) 5840 139 0 0 86 0 ribosome 5830 64 0 0 63 0 cytosolic ribosome (sensu Eukarya) 5829 213 0 0 127 0 cytosol 5783 194 0 0 67 0 endoplasmic reticulum 5746 24 0 0 18 0 mitochondrial electron transport chain 5743 81 0 0 32 0 mitochondrial inner membrane 5740 107 0 0 37 0 mitochondrial membrane 5739 369 0 0 109 0 mitochondrion 5737 1718 0 0 484 0 cytoplasm 5681 35 0 0 20 0 spliceosome complex 5667 266 0 0 21 0 transcription factor complex 5622 3016 0 0 691 0 intracellular 5615 1349 0 0 164 0 extracellular space 5578 189 0 0 14 0 extracellular matrix 5576 1455 0 0 173 0 extracellular 502 27 0 0 17 0 proteasome complex (sensu Eukarya) 5261 151 0 0 2 0 cation channel activity 5244 90 0 0 1 0 voltage-gated ion channel activity 5216 221 0 0 10 0 ion channel activity 313 66 0 0 29 0 organellar ribosome 312 8 0 0 8 0 plastid small ribosomal subunit 311 8 0 0 8 0 plastid large ribosomal subunit 5198 366 0 0 124 0 structural molecule activity 5179 68 0 0 1 0 hormone activity 5102 265 0 0 16 0 receptor binding 15992 37 0 0 23 0 proton transport 15980 97 0 0 35 0 energy derivation by oxidation of organic compounds 15935 48 0 0 34 0 small ribosomal subunit 15934 62 0 0 40 0 large ribosomal subunit 3773 29 0 0 16 0 heat shock protein activity 3754 80 0 0 34 0 chaperone activity 3743 32 0 0 19 0 translation initiation factor activity 3735 136 0 0 84 0 structural constituent of ribosome 3729 40 0 0 19 0 mRNA binding 3723 223 0 0 102 0 RNA binding 3700 492 0 0 34 0 transcription factor activity 8553 32 0 0 18 0 hydrogen-exporting ATPase activity 15662 58 0 0 24 0 P-type ATPase activity 46728 17 0 0 11 0 viral capsid (sensu Retroviridae) 8380 59 0 0 31 0 RNA splicing 8324 119 0 0 46 0 cation transporter activity 8248 30 0 0 16 0 pre-mRNA splicing factor activity 15399 135 0 0 51 0 primary active transporter activity 8152 3085 0 0 647 0 metabolism 8135 52 0 0 26 0 "translation factor activity, nucleic acid binding" 15268 243 0 0 11 0 alpha-type channel activity 15267 247 0 0 11 0 channel/pore class transporter activity 46365 40 0 0 19 0 monosaccharide catabolism 8083 103 0 0 3 0 growth factor activity 6511 89 0 0 32 0.0001 ubiquitin-dependent protein catabolism 1653 77 0 0 2 0.0001 peptide receptor activity 6468 321 0 0 33 0.0001 protein amino acid phosphorylation 16616 47 0 0 20 0.0001 "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" 16614 51 0 0 21 0.0001 "oxidoreductase activity, acting on CH-OH group of donors" 4357 2 0 0 2 0.0001 glutamate-cysteine ligase activity 9142 27 0 0 14 0.0001 nucleoside triphosphate biosynthesis 9141 30 0 0 15 0.0001 nucleoside triphosphate metabolism 19941 91 0 0 32 0.0001 protein-ligand dependent protein catabolism 7389 84 0 0 3 0.0001 pattern specification 5874 31 0 0 15 0.0001 microtubule 5839 16 0 0 10 0.0001 proteasome core complex (sensu Eukarya) 314 27 0 0 14 0.0001 organellar small ribosomal subunit 8528 77 0 0 2 0.0001 "peptide receptor activity, G-protein coupled" 3677 925 0 0 124 0.0001 DNA binding 6878 5 0 0 5 0.0002 copper ion homeostasis 6732 71 0 0 26 0.0002 coenzyme metabolism 6163 48 0 0 20 0.0002 purine nucleotide metabolism 16745 5 0 0 5 0.0002 transketolase and transaldolase activity 16744 5 0 0 5 0.0002 "transferase activity, transferring aldehyde or ketonic groups" 4029 7 0 0 6 0.0002 aldehyde dehydrogenase (NAD+) activity 19226 112 0 0 6 0.0002 transmission of nerve impulse 45277 9 0 0 7 0.0002 respiratory chain complex IV 5751 9 0 0 7 0.0002 respiratory chain complex IV (sensu Eukarya) 5732 9 0 0 7 0.0002 small nucleolar ribonucleoprotein complex 6796 395 0 0 45 0.0003 phosphate metabolism 6793 395 0 0 45 0.0003 phosphorus metabolism 4713 248 0 0 24 0.0003 protein tyrosine kinase activity 5654 366 0 0 41 0.0003 nucleoplasm 5525 138 0 0 42 0.0003 GTP binding 6445 18 0 0 10 0.0004 regulation of translation 6099 18 0 0 10 0.0004 tricarboxylic acid cycle 6096 34 0 0 15 0.0004 glycolysis 16820 102 0 0 33 0.0004 "hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances" 4674 342 0 0 38 0.0004 protein serine/threonine kinase activity 42626 102 0 0 33 0.0004 "ATPase activity, coupled to transmembrane movement of substances" 42277 88 0 0 4 0.0004 peptide binding 7155 266 0 0 27 0.0004 cell adhesion 45279 10 0 0 7 0.0004 NADH dehydrogenase complex (ubiquinone) 45271 10 0 0 7 0.0004 respiratory chain complex I 5747 10 0 0 7 0.0004 respiratory chain complex I (sensu Eukarya) 15405 111 0 0 35 0.0004 P-P-bond-hydrolysis-driven transporter activity 16310 326 0 0 36 0.0005 phosphorylation 6376 13 0 0 8 0.0006 mRNA splice site selection 9408 22 0 0 11 0.0006 response to heat 5773 68 0 0 24 0.0006 vacuole 6979 16 0 0 9 0.0007 response to oxidative stress 6446 8 0 0 6 0.0007 regulation of translational initiation 6414 16 0 0 9 0.0007 translational elongation 6006 57 0 0 21 0.0007 glucose metabolism 5730 50 0 0 19 0.0007 nucleolus 6935 51 0 0 1 0.0008 chemotaxis 16818 296 0 0 76 0.0008 "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" 42330 51 0 0 1 0.0008 taxis 6955 209 0 0 20 0.0009 immune response 9108 33 0 0 14 0.0009 coenzyme biosynthesis 3824 2356 0 0 474 0.0009 catalytic activity 15081 11 0 0 7 0.001 sodium ion transporter activity 6563 4 0 0 4 0.001 serine metabolism 16684 23 0 0 11 0.001 "oxidoreductase activity, acting on peroxide as acceptor" 4601 23 0 0 11 0.001 peroxidase activity 16469 11 0 0 7 0.001 proton-transporting two-sector ATPase complex 19012 23 0 0 11 0.001 virion 5838 4 0 0 4 0.001 proteasome regulatory particle (sensu Eukarya) 5832 6 0 0 5 0.001 chaperonin-containing T-complex 8137 11 0 0 7 0.001 NADH dehydrogenase (ubiquinone) activity 6731 87 0 0 28 0.0011 coenzymes and prosthetic group metabolism 9266 30 0 0 13 0.0011 response to temperature 5125 138 0 0 11 0.0011 cytokine activity 4896 49 0 0 1 0.0012 hematopoietin/interferon-class (D200-domain) cytokine receptor activity 16817 301 0 0 76 0.0012 "hydrolase activity, acting on acid anhydrides" 16659 14 0 0 8 0.0012 "oxidoreductase activity, acting on NADH or NADPH, other acceptor" 19955 49 0 0 1 0.0012 cytokine binding 5544 14 0 0 8 0.0012 calcium-dependent phospholipid binding 4672 376 0 0 45 0.0014 protein kinase activity 6752 24 0 0 11 0.0015 group transfer coenzyme metabolism 9314 57 0 0 2 0.0016 response to radiation 8150 5525 0 0 958 0.0016 biological_process 6813 87 0 0 5 0.0017 potassium ion transport 4028 9 0 0 6 0.0017 aldehyde dehydrogenase activity 8435 9 0 0 6 0.0017 anticoagulant activity 15291 102 0 0 7 0.0017 porter activity 15290 103 0 0 7 0.0017 electrochemical potential-driven transporter activity 42623 153 0 0 43 0.0019 "ATPase activity, coupled" 16773 423 0 0 53 0.0021 "phosphotransferase activity, alcohol group as acceptor" 46916 15 0 0 8 0.0021 transition metal ion homeostasis 8430 15 0 0 8 0.0021 selenium binding 9416 55 0 0 2 0.0024 response to light 16887 174 0 0 47 0.0026 ATPase activity 6936 44 0 0 1 0.0027 muscle contraction 6811 353 0 0 43 0.0027 ion transport 6740 7 0 0 5 0.0029 NADPH regeneration 6098 7 0 0 5 0.0029 pentose-phosphate shunt 19001 179 0 0 48 0.003 guanyl nucleotide binding 4840 19 0 0 9 0.0031 ubiquitin conjugating enzyme activity 46907 295 0 0 73 0.0031 intracellular transport 8639 19 0 0 9 0.0031 small protein conjugating enzyme activity 6066 117 0 0 34 0.0033 alcohol metabolism 315 36 0 0 14 0.0033 organellar large ribosomal subunit 45255 10 0 0 6 0.0036 hydrogen-translocating F-type ATPase complex 3954 10 0 0 6 0.0036 NADH dehydrogenase activity 323 60 0 0 20 0.0037 lytic vacuole 16655 13 0 0 7 0.0038 "oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor" 5625 23 0 0 10 0.0041 soluble fraction 7582 4553 0 0 861 0.0043 physiological processes 6564 3 0 0 4 0.0045 serine biosynthesis 6493 5 0 0 4 0.0045 O-linked glycosylation 16801 5 0 0 4 0.0045 "hydrolase activity, acting on ether bonds" 4653 5 0 0 4 0.0045 polypeptide N-acetylgalactosaminyltransferase activity 16228 5 0 0 4 0.0045 aldolase activity 5853 5 0 0 4 0.0045 eukaryotic translation elongation factor 1 complex 5786 5 0 0 4 0.0045 signal recognition particle 5543 20 0 0 9 0.0048 phospholipid binding 9165 57 0 0 19 0.0049 nucleotide biosynthesis 7017 89 0 0 27 0.0049 microtubule-based process 6512 34 0 0 13 0.0054 ubiquitin cycle 16881 34 0 0 13 0.0054 acid-D-amino acid ligase activity 6767 17 0 0 8 0.0056 water-soluble vitamin metabolism 9850 3 0 0 3 0.0058 auxin metabolism 4859 3 0 0 3 0.0058 phospholipase inhibitor activity 4802 3 0 0 3 0.0058 transketolase activity 16654 3 0 0 3 0.0058 "oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor" 16272 3 0 0 3 0.0058 prefoldin complex 19834 3 0 0 3 0.0058 phospholipase A2 inhibitor activity 5945 3 0 0 3 0.0058 6-phosphofructokinase complex 5837 3 0 0 3 0.0058 26S proteasome 3872 3 0 0 3 0.0058 6-phosphofructokinase activity 5764 53 0 0 18 0.0059 lysosome 4252 93 0 0 7 0.0061 serine-type endopeptidase activity 6952 276 0 0 33 0.0064 defense response 6769 8 0 0 5 0.0065 nicotinamide metabolism 6749 8 0 0 5 0.0065 glutathione metabolism 6739 8 0 0 5 0.0065 NADPH metabolism 19362 8 0 0 5 0.0065 pyridine nucleotide metabolism 7018 21 0 0 9 0.0071 microtubule-based movement 5815 21 0 0 9 0.0071 microtubule organizing center 6800 31 0 0 12 0.0074 oxygen and reactive oxygen species metabolism 16301 498 0 0 68 0.0076 kinase activity 9583 49 0 0 2 0.0078 perception of light 12505 89 0 0 26 0.0081 endomembrane system 8236 100 0 0 8 0.0081 serine-type peptidase activity 19318 72 0 0 22 0.0083 hexose metabolism 6996 320 0 0 76 0.0088 organelle organization and biogenesis 6820 83 0 0 6 0.0089 anion transport 46138 44 0 0 15 0.0094 coenzymes and prosthetic group biosynthesis 6816 38 0 0 1 0.0094 calcium ion transport 5623 4506 0 0 849 0.0095 cell 6323 94 0 0 27 0.0097 DNA packaging 6281 104 0 0 9 0.0098 DNA repair 30705 22 0 0 9 0.0101 cytoskeleton-dependent intracellular transport 5763 22 0 0 9 0.0101 mitochondrial small ribosomal subunit 46873 22 0 0 9 0.0101 metal ion transporter activity 15031 241 0 0 59 0.0102 protein transport 16838 1 0 0 1 0.0103 "carbon-oxygen lyase activity, acting on phosphates" 16756 1 0 0 1 0.0103 glutathione gamma-glutamylcysteinyltransferase activity 4616 1 0 0 1 0.0103 phosphogluconate dehydrogenase (decarboxylating) activity 16404 1 0 0 1 0.0103 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 9051 1 0 0 1 0.0103 "pentose-phosphate shunt, oxidative branch" 4128 1 0 0 1 0.0103 cytochrome b5 reductase activity 17109 1 0 0 1 0.0103 glutamate-cysteine ligase complex 3874 1 0 0 1 0.0103 6-pyruvoyltetrahydropterin synthase activity 8543 1 0 0 1 0.0103 FGF receptor signaling pathway 8114 1 0 0 1 0.0103 6-phosphogluconate 2-dehydrogenase activity 6118 198 0 0 50 0.0109 electron transport 6081 6 0 0 4 0.0115 aldehyde metabolism 9889 6 0 0 4 0.0115 regulation of biosynthesis 16573 6 0 0 4 0.0115 histone acetylation 9070 6 0 0 4 0.0115 serine family amino acid biosynthesis 7149 6 0 0 4 0.0115 colony morphology 7125 6 0 0 4 0.0115 invasive growth 27 6 0 0 4 0.0115 ribosomal large subunit assembly and maintenance 8376 6 0 0 4 0.0115 acetylgalactosaminyltransferase activity 6733 12 0 0 6 0.0116 oxidoreduction coenzyme metabolism 45333 12 0 0 6 0.0116 cellular respiration 5774 12 0 0 6 0.0116 vacuolar membrane 16788 289 0 0 36 0.012 "hydrolase activity, acting on ester bonds" 5057 80 0 0 6 0.012 receptor signaling protein activity 5516 55 0 0 3 0.0124 calmodulin binding 6487 9 0 0 5 0.0125 N-linked glycosylation 16570 9 0 0 5 0.0125 histone modification 16569 9 0 0 5 0.0125 covalent chromatin modification 9060 9 0 0 5 0.0125 aerobic respiration 45259 9 0 0 5 0.0125 proton-transporting ATP synthase complex 5753 9 0 0 5 0.0125 proton-transporting ATP synthase complex (sensu Eukarya) 5996 73 0 0 22 0.0131 monosaccharide metabolism 6886 231 0 0 56 0.0145 intracellular protein transport 6260 95 0 0 8 0.0146 DNA replication 9117 87 0 0 25 0.0159 nucleotide metabolism 4 338 0 0 78 0.0162 biological_process unknown 8372 429 0 0 96 0.0162 cellular_component unknown 7600 77 0 0 6 0.0164 sensory perception 7156 44 0 0 2 0.0166 homophilic cell adhesion 15293 44 0 0 2 0.0166 symporter activity 6974 121 0 0 12 0.0168 response to DNA damage stimulus 3702 68 0 0 5 0.0172 RNA polymerase II transcription factor activity 5554 393 0 0 89 0.0176 molecular_function unknown 3774 52 0 0 3 0.0176 motor activity 7610 60 0 0 4 0.0177 behavior 226 27 0 0 10 0.0197 microtubule cytoskeleton organization and biogenesis 4791 2 0 0 3 0.0201 thioredoxin reductase (NADPH) activity 8540 2 0 0 3 0.0201 "proteasome regulatory particle, base subcomplex (sensu Eukarya)" 6750 4 0 0 3 0.0202 glutathione biosynthesis 6623 4 0 0 3 0.0202 protein-vacuolar targeting 6120 4 0 0 3 0.0202 "oxidative phosphorylation, NADH to ubiquinone" 6108 4 0 0 3 0.0202 malate metabolism 6097 4 0 0 3 0.0202 glyoxylate cycle 9814 4 0 0 3 0.0202 response to pathogen (incompatible interaction) 16962 4 0 0 3 0.0202 receptor-associated protein activity 16615 4 0 0 3 0.0202 malate dehydrogenase activity 16453 4 0 0 3 0.0202 C-acetyltransferase activity 7040 4 0 0 3 0.0202 lysosome organization and biogenesis 5224 4 0 0 3 0.0202 ATP-binding and phosphorylation-dependent chloride channel activity 3985 4 0 0 3 0.0202 acetyl-CoA C-acetyltransferase activity 46487 4 0 0 3 0.0202 glyoxylate metabolism 4090 2 0 0 1 0.0206 carbonyl reductase (NADPH) activity 40023 2 0 0 1 0.0206 nuclear positioning 8934 2 0 0 1 0.0206 myo-inositol-1(or 4)-monophosphatase activity 8106 2 0 0 1 0.0206 alcohol dehydrogenase (NADP+) activity 5581 32 0 0 1 0.021 collagen 6473 10 0 0 5 0.0213 protein amino acid acetylation 7242 395 0 0 54 0.0215 intracellular signaling cascade 5489 121 0 0 32 0.0224 electron transporter activity 42257 7 0 0 4 0.0231 ribosomal subunit assembly 42255 7 0 0 4 0.0231 ribosome assembly 5386 270 0 0 63 0.0234 carrier activity 9056 489 0 0 107 0.0235 catabolism 30005 28 0 0 10 0.0235 "di-, tri-valent inorganic cation homeostasis" 16853 77 0 0 22 0.0238 isomerase activity 1527 42 0 0 2 0.0245 microfibril 7517 58 0 0 4 0.0247 muscle development 30154 126 0 0 13 0.0253 cell differentiation 7218 51 0 0 3 0.0259 neuropeptide signaling pathway 72 14 0 0 6 0.0272 M-phase specific microtubule process 9581 81 0 0 7 0.028 perception of external stimulus 4842 29 0 0 10 0.0284 ubiquitin-protein ligase activity 19897 29 0 0 10 0.0284 extrinsic to plasma membrane 16772 501 0 0 72 0.0292 "transferase activity, transferring phosphorus-containing groups" 5761 53 0 0 16 0.0295 mitochondrial ribosome 16620 18 0 0 7 0.0304 "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" 3746 18 0 0 7 0.0304 translation elongation factor activity 15276 73 0 0 6 0.0306 ligand-gated ion channel activity 46146 3 0 0 1 0.0307 tetrahydrobiopterin metabolism 6729 3 0 0 1 0.0307 tetrahydrobiopterin biosynthesis 6325 84 0 0 23 0.0312 establishment and/or maintenance of chromatin architecture 30020 30 0 0 1 0.0314 extracellular matrix structural constituent conferring tensile strength activity 45045 74 0 0 21 0.0315 secretory pathway 4907 31 0 0 1 0.0319 interleukin receptor activity 19965 31 0 0 1 0.0319 interleukin binding 16859 25 0 0 9 0.032 cis-trans isomerase activity 3755 25 0 0 9 0.032 peptidyl-prolyl cis-trans isomerase activity 6677 2 0 0 2 0.0324 glycosylceramide metabolism 6045 2 0 0 2 0.0324 N-acetylglucosamine biosynthesis 6042 2 0 0 2 0.0324 glucosamine biosynthesis 9851 2 0 0 2 0.0324 auxin biosynthesis 16815 2 0 0 2 0.0324 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles" 16802 2 0 0 2 0.0324 thioether hydrolase activity 4801 2 0 0 2 0.0324 transaldolase activity 9684 2 0 0 2 0.0324 indoleacetic acid biosynthesis 9683 2 0 0 2 0.0324 indoleacetic acid metabolism 9626 2 0 0 2 0.0324 hypersensitive response 16600 2 0 0 2 0.0324 flotillin complex 9497 2 0 0 2 0.0324 3Fe-4S/4Fe-4S electron transfer carrier 16599 2 0 0 2 0.0324 caveolar membrane 4594 2 0 0 2 0.0324 pantothenate kinase activity 4579 2 0 0 2 0.0324 dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity 16433 2 0 0 2 0.0324 rRNA (adenine) methyltransferase activity 4459 2 0 0 2 0.0324 L-lactate dehydrogenase activity 4457 2 0 0 2 0.0324 lactate dehydrogenase activity 42546 2 0 0 2 0.0324 cell wall biosynthesis 4030 2 0 0 2 0.0324 aldehyde dehydrogenase (NAD(P)+) activity 4013 2 0 0 2 0.0324 adenosylhomocysteinase activity 30060 2 0 0 2 0.0324 L-malate dehydrogenase activity 30032 2 0 0 2 0.0324 lamellipodium formation 7098 2 0 0 2 0.0324 centrosome cycle 7041 2 0 0 2 0.0324 lysosomal transport 45120 2 0 0 2 0.0324 pronucleus 5852 2 0 0 2 0.0324 eukaryotic translation initiation factor 3 complex 5640 2 0 0 2 0.0324 nuclear outer membrane 749 2 0 0 2 0.0324 response to pheromone during conjugation with cellular fusion 257 2 0 0 2 0.0324 nitrilase activity 5093 2 0 0 2 0.0324 RAB GDP-dissociation inhibitor activity 5055 2 0 0 2 0.0324 laminin receptor activity 179 2 0 0 2 0.0324 "rRNA (adenine-N6,N6-)-dimethyltransferase activity" 3955 2 0 0 2 0.0324 NAD(P)H dehydrogenase (quinone) activity 8649 2 0 0 2 0.0324 rRNA methyltransferase activity 8600 2 0 0 2 0.0324 "protein phosphatase type 2A, catalyst activity" 8356 2 0 0 2 0.0324 asymmetric cytokinesis 3924 111 0 0 29 0.0332 GTPase activity 9605 466 0 0 67 0.0335 response to external stimulus 4518 56 0 0 4 0.0346 nuclease activity 6261 39 0 0 2 0.035 DNA dependent DNA replication 16337 57 0 0 4 0.0355 cell-cell adhesion 42578 161 0 0 19 0.0376 phosphoric ester hydrolase activity 7033 15 0 0 6 0.0386 vacuole organization and biogenesis 6605 104 0 0 27 0.0392 protein targeting 5768 21 0 0 8 0.0394 endosome 7052 8 0 0 4 0.0397 mitotic spindle assembly 5885 8 0 0 4 0.0397 Arp2/3 protein complex 46474 8 0 0 4 0.0397 glycerophospholipid biosynthesis 6020 4 0 0 1 0.0407 myo-inositol metabolism 6464 523 0 0 77 0.0436 protein modification 6417 5 0 0 3 0.0437 regulation of protein biosynthesis 6119 5 0 0 3 0.0437 oxidative phosphorylation 4602 5 0 0 3 0.0437 glutathione peroxidase activity 16471 5 0 0 3 0.0437 hydrogen-translocating V-type ATPase complex 16284 5 0 0 3 0.0437 alanine aminopeptidase activity 4179 5 0 0 3 0.0437 membrane alanyl aminopeptidase activity 19843 5 0 0 3 0.0437 rRNA binding 19236 5 0 0 3 0.0437 response to pheromone 7030 5 0 0 3 0.0437 Golgi organization and biogenesis 5758 5 0 0 3 0.0437 mitochondrial intermembrane space 5092 5 0 0 3 0.0437 GDP-dissociation inhibitor activity 49 5 0 0 3 0.0437 tRNA binding 15986 5 0 0 3 0.0437 ATP synthesis coupled proton transport 15985 5 0 0 3 0.0437 "energy coupled proton transport, down the electrochemical gradient" 8443 5 0 0 3 0.0437 phosphofructokinase activity 16407 27 0 0 9 0.0457 acetyltransferase activity 42175 27 0 0 9 0.0457 nuclear envelope-endoplasmic reticulum network 9719 126 0 0 14 0.0458 response to endogenous stimulus 9613 126 0 0 14 0.0458 response to pest/pathogen/parasite 6486 35 0 0 11 0.0467 protein amino acid glycosylation 9101 35 0 0 11 0.0467 glycoprotein biosynthesis 8015 29 0 0 1 0.0484 circulation 5604 29 0 0 1 0.0484 basement membrane 6094 12 0 0 5 0.0488 gluconeogenesis 16126 12 0 0 5 0.0488 sterol biosynthesis 5925 12 0 0 5 0.0488 focal adhesion 5924 12 0 0 5 0.0488 cell-substrate adherens junction 6997 115 0 0 29 0.0495 nuclear organization and biogenesis 7399 165 0 0 20 0.0506 neurogenesis 15020 5 0 0 1 0.0507 glucuronosyltransferase activity 15849 37 0 0 2 0.0509 organic acid transport 46942 37 0 0 2 0.0509 carboxylic acid transport 4879 46 0 0 3 0.0513 ligand-dependent nuclear receptor activity 3707 46 0 0 3 0.0513 steroid hormone receptor activity 6875 30 0 0 10 0.0515 metal ion homeostasis 6766 23 0 0 8 0.0518 vitamin metabolism 4177 23 0 0 8 0.0518 aminopeptidase activity 5975 186 0 0 44 0.0522 carbohydrate metabolism 19898 31 0 0 10 0.0563 extrinsic to membrane 7001 107 0 0 27 0.0566 chromosome organization and biogenesis (sensu Eukarya) 67 122 0 0 14 0.0575 DNA replication and chromosome cycle 4295 58 0 0 5 0.0603 trypsin activity 15359 6 0 0 1 0.0605 amino acid permease activity 6334 24 0 0 8 0.0612 nucleosome assembly 15674 60 0 0 5 0.0612 "di-, tri-valent inorganic cation transport" 7051 9 0 0 4 0.0615 spindle assembly 5217 9 0 0 4 0.0615 intracellular ligand-gated ion channel activity 160 9 0 0 4 0.0615 two-component signal transduction system (phosphorelay) 9582 72 0 0 7 0.0653 perception of abiotic stimulus 7167 116 0 0 13 0.0662 enzyme linked receptor protein signaling pathway 4659 13 0 0 5 0.0679 prenyltransferase activity 30055 13 0 0 5 0.0679 cell-matrix junction 5884 13 0 0 5 0.0679 actin filament 158 13 0 0 5 0.0679 protein phosphatase type 2A activity 42592 53 0 0 15 0.0698 homeostasis 19725 53 0 0 15 0.0698 cell homeostasis 46943 42 0 0 3 0.07 carboxylic acid transporter activity 16782 25 0 0 1 0.0701 "transferase activity, transferring sulfur-containing groups" 6559 7 0 0 1 0.0702 phenylalanine catabolism 42559 7 0 0 1 0.0702 pteridine and derivative biosynthesis 42558 7 0 0 1 0.0702 pteridine and derivative metabolism 8066 26 0 0 1 0.0706 glutamate receptor activity 7599 43 0 0 3 0.0707 hemostasis 5342 43 0 0 3 0.0707 organic acid transporter activity 139 20 0 0 7 0.0722 Golgi membrane 16055 27 0 0 1 0.0734 Wnt receptor signaling pathway 7187 27 0 0 1 0.0734 "G-protein signaling, coupled to cyclic nucleotide second messenger" 7179 27 0 0 1 0.0734 TGFbeta receptor signaling pathway 6611 6 0 0 3 0.0758 protein-nucleus export 4448 6 0 0 3 0.0758 isocitrate dehydrogenase activity 30703 6 0 0 3 0.0758 eggshell formation 16358 6 0 0 3 0.0758 dendrite morphogenesis 19904 6 0 0 3 0.0758 protein domain specific binding 7304 6 0 0 3 0.0758 eggshell formation (sensu Insecta) 7150 6 0 0 3 0.0758 growth pattern 7124 6 0 0 3 0.0758 pseudohyphal growth 124 6 0 0 3 0.0758 SAGA complex 9100 36 0 0 11 0.0773 glycoprotein metabolism 278 204 0 0 27 0.0783 mitotic cell cycle 16765 28 0 0 9 0.0785 "transferase activity, transferring alkyl or aryl (other than methyl) groups" 16125 28 0 0 9 0.0785 sterol metabolism 9607 305 0 0 43 0.0788 response to biotic stimulus 6558 8 0 0 1 0.0798 phenylalanine metabolism 9074 8 0 0 1 0.0798 aromatic amino acid family catabolism 7049 433 0 0 64 0.0803 cell cycle 16879 58 0 0 16 0.0834 "ligase activity, forming carbon-nitrogen bonds" 15035 3 0 0 2 0.0855 protein disulfide oxidoreductase activity 6921 3 0 0 2 0.0855 disassembly of cell structures 6882 1 0 0 2 0.0855 zinc ion homeostasis 10016 3 0 0 2 0.0855 shoot morphogenesis 6664 3 0 0 2 0.0855 glycolipid metabolism 6658 3 0 0 2 0.0855 phosphatidylserine metabolism 6614 3 0 0 2 0.0855 SRP-dependent cotranslational membrane targeting 18401 3 0 0 2 0.0855 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 6309 3 0 0 2 0.0855 DNA fragmentation 6125 1 0 0 2 0.0855 thioredoxin pathway 9965 3 0 0 2 0.0855 leaf morphogenesis 16864 3 0 0 2 0.0855 "intramolecular isomerase activity, transposing S-S bonds" 16842 3 0 0 2 0.0855 amidine-lyase activity 16803 3 0 0 2 0.0855 ether hydrolase activity 16652 3 0 0 2 0.0855 "oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor" 4667 3 0 0 2 0.0855 prostaglandin-D synthase activity 4656 3 0 0 2 0.0855 "procollagen-proline,2-oxoglutarate-4-dioxygenase activity" 4617 1 0 0 2 0.0855 phosphoglycerate dehydrogenase activity 4576 3 0 0 2 0.0855 oligosaccharyl transferase activity 4470 3 0 0 2 0.0855 malic enzyme activity 4463 3 0 0 2 0.0855 leukotriene-A4 hydrolase activity 4450 3 0 0 2 0.0855 isocitrate dehydrogenase (NADP+) activity 9294 3 0 0 2 0.0855 DNA mediated transformation 9292 3 0 0 2 0.0855 genetic transfer 9290 3 0 0 2 0.0855 cellular DNA uptake 4214 1 0 0 2 0.0855 dipeptidyl-peptidase I activity 42435 3 0 0 2 0.0855 indole derivative biosynthesis 16132 3 0 0 2 0.0855 brassinosteroid biosynthesis 16131 3 0 0 2 0.0855 brassinosteroid metabolism 16129 3 0 0 2 0.0855 phytosteroid biosynthesis 16128 3 0 0 2 0.0855 phytosteroid metabolism 16072 3 0 0 2 0.0855 rRNA metabolism 4017 3 0 0 2 0.0855 adenylate kinase activity 30262 3 0 0 2 0.0855 apoptotic nuclear changes 30138 3 0 0 2 0.0855 COPII-coated vesicle 19798 3 0 0 2 0.0855 procollagen-proline dioxygenase activity 30031 3 0 0 2 0.0855 formation of a cell surface projection 30030 3 0 0 2 0.0855 cell surface structure organization and biogenesis 19511 3 0 0 2 0.0855 peptidyl-proline hydroxylation 7520 3 0 0 2 0.0855 myoblast fusion 19471 3 0 0 2 0.0855 4-hydroxyproline metabolism 19430 1 0 0 2 0.0855 removal of superoxide radicals 7306 3 0 0 2 0.0855 insect chorion formation 45597 3 0 0 2 0.0855 positive regulation of cell differentiation 19005 3 0 0 2 0.0855 SCF ubiquitin ligase complex 5960 1 0 0 2 0.0855 glycine cleavage complex 5344 3 0 0 2 0.0855 oxygen transporter activity 320 3 0 0 2 0.0855 re-entry into mitotic cell cycle 245 3 0 0 2 0.0855 spliceosome assembly 154 3 0 0 2 0.0855 rRNA modification 153 3 0 0 2 0.0855 cytoplasmic ubiquitin ligase complex 42 3 0 0 2 0.0855 protein-Golgi targeting 3756 3 0 0 2 0.0855 protein disulfide isomerase activity 46843 3 0 0 2 0.0855 dorsal appendage formation 8538 3 0 0 2 0.0855 proteasome activator activity 8537 3 0 0 2 0.0855 proteasome activator complex 8173 3 0 0 2 0.0855 RNA methyltransferase activity 46349 3 0 0 2 0.0855 amino sugar biosynthesis 3793 71 0 0 7 0.0862 defense/immunity protein activity 5215 869 0 0 138 0.0879 transporter activity 6100 10 0 0 4 0.0883 TCA intermediate metabolism 9069 10 0 0 4 0.0883 serine family amino acid metabolism 5813 10 0 0 4 0.0883 centrosome 5635 38 0 0 11 0.0891 nuclear membrane 166 1003 0 0 200 0.0898 nucleotide binding 4263 49 0 0 4 0.0906 chymotrypsin activity 4866 61 0 0 16 0.0955 endopeptidase inhibitor activity 30414 61 0 0 16 0.0955 protease inhibitor activity 6139 1270 0 0 208 0.0956 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" 7243 62 0 0 6 0.0967 protein kinase cascade 42598 39 0 0 11 0.0976 vesicular fraction 30003 39 0 0 11 0.0976 cation homeostasis 5792 39 0 0 11 0.0976 microsome 5905 22 0 0 7 0.0977 coated pit 8081 40 0 0 3 0.0978 phosphoric diester hydrolase activity 17076 997 0 0 198 0.098 purine nucleotide binding 19438 10 0 0 1 0.0988 aromatic compound biosynthesis 16740 824 0 0 131 0.0992 transferase activity 4857 92 0 0 23 0.0994 enzyme inhibitor activity 7596 41 0 0 3 0.0995 blood coagulation 5759 78 0 0 20 0.1009 mitochondrial matrix 6873 42 0 0 12 0.1031 cell ion homeostasis 8283 504 0 0 77 0.1033 cell proliferation 3823 23 0 0 1 0.1041 antigen binding 1505 32 0 0 2 0.1043 regulation of neurotransmitter levels 9795 32 0 0 2 0.1043 embryonic morphogenesis 7188 24 0 0 1 0.1059 "G-protein signaling, coupled to cAMP nucleotide second messenger" 7417 33 0 0 2 0.1072 central nervous system development 30574 11 0 0 1 0.1081 collagen catabolism 785 53 0 0 14 0.1089 chromatin 30163 339 0 0 72 0.1108 protein catabolism 16903 25 0 0 8 0.1109 "oxidoreductase activity, acting on the aldehyde or oxo group of donors" 18346 7 0 0 3 0.1154 protein amino acid prenylation 16706 7 0 0 3 0.1154 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 5665 7 0 0 3 0.1154 "DNA-directed RNA polymerase II, core complex" 46467 18 0 0 6 0.1167 membrane lipid biosynthesis 5200 57 0 0 15 0.1172 structural constituent of cytoskeleton 84 101 0 0 12 0.1175 S phase of mitotic cell cycle 4364 11 0 0 4 0.1197 glutathione transferase activity 3899 11 0 0 4 0.1197 DNA-directed RNA polymerase activity 3725 11 0 0 4 0.1197 double-stranded RNA binding 7169 61 0 0 6 0.1294 transmembrane receptor protein tyrosine kinase signaling pathway 4175 172 0 0 23 0.1307 endopeptidase activity 16776 19 0 0 6 0.1337 "phosphotransferase activity, phosphate group as acceptor" 5819 19 0 0 6 0.1337 spindle 40007 19 0 0 6 0.1337 growth 3676 1231 0 0 240 0.1385 nucleic acid binding 8289 78 0 0 19 0.1399 lipid binding 16874 115 0 0 27 0.1406 ligase activity 9790 79 0 0 9 0.141 embryonic development 6508 331 0 0 70 0.1417 proteolysis and peptidolysis 6364 28 0 0 8 0.1432 rRNA processing 6366 139 0 0 18 0.1459 transcription from Pol II promoter 15837 29 0 0 2 0.1475 amine/polyamine transport 15698 53 0 0 5 0.148 inorganic anion transport 46037 4 0 0 2 0.1509 GMP metabolism 6506 4 0 0 2 0.1509 GPI anchor biosynthesis 6303 4 0 0 2 0.1509 double-strand break repair via nonhomologous end-joining 18208 4 0 0 2 0.1509 peptidyl-proline modification 9725 4 0 0 2 0.1509 response to hormone stimulus 16832 4 0 0 2 0.1509 aldehyde-lyase activity 16774 4 0 0 2 0.1509 "phosphotransferase activity, carboxyl group as acceptor" 4785 4 0 0 2 0.1509 "copper, zinc superoxide dismutase activity" 16742 4 0 0 2 0.1509 "hydroxymethyl-, formyl- and related transferase activity" 4680 4 0 0 2 0.1509 casein kinase activity 16363 4 0 0 2 0.1509 nuclear matrix 4111 4 0 0 2 0.1509 creatine kinase activity 19863 4 0 0 2 0.1509 IgE binding 5935 4 0 0 2 0.1509 bud neck 5933 4 0 0 2 0.1509 bud 5901 4 0 0 2 0.1509 caveola 5890 4 0 0 2 0.1509 sodium/potassium-exchanging ATPase complex 5736 4 0 0 2 0.1509 DNA-directed RNA polymerase I complex 5638 4 0 0 2 0.1509 lamin filament 780 4 0 0 2 0.1509 "condensed nuclear chromosome, pericentric region" 779 4 0 0 2 0.1509 "condensed chromosome, pericentric region" 778 4 0 0 2 0.1509 condensed nuclear chromosome kinetochore 777 4 0 0 2 0.1509 condensed chromosome kinetochore 329 4 0 0 2 0.1509 vacuolar membrane (sensu Fungi) 302 4 0 0 2 0.1509 response to reactive oxygen species 5007 4 0 0 2 0.1509 fibroblast growth factor receptor activity 187 4 0 0 2 0.1509 activation of MAPK 15991 4 0 0 2 0.1509 ATP hydrolysis coupled proton transport 46489 4 0 0 2 0.1509 phosphoinositide biosynthesis 8199 4 0 0 2 0.1509 ferric iron binding 15280 4 0 0 2 0.1509 amiloride-sensitive sodium channel activity 46165 14 0 0 5 0.1525 alcohol biosynthesis 19319 14 0 0 5 0.1525 hexose biosynthesis 19222 14 0 0 5 0.1525 regulation of metabolism 8654 14 0 0 5 0.1525 phospholipid biosynthesis 46364 14 0 0 5 0.1525 monosaccharide biosynthesis 16860 20 0 0 6 0.1542 intramolecular isomerase activity 910 20 0 0 6 0.1542 cytokinesis 5643 20 0 0 6 0.1542 nuclear pore 46930 20 0 0 6 0.1542 pore complex 4112 21 0 0 1 0.1547 cyclic-nucleotide phosphodiesterase activity 16791 125 0 0 16 0.1573 phosphoric monoester hydrolase activity 30097 22 0 0 1 0.1587 hemopoiesis 7015 22 0 0 1 0.1587 actin filament organization 5575 5367 0 0 949 0.1589 cellular_component 15071 8 0 0 3 0.1608 protein phosphatase type 2C activity 46051 8 0 0 3 0.1608 UTP metabolism 46039 8 0 0 3 0.1608 GTP metabolism 46036 8 0 0 3 0.1608 CTP metabolism 6803 8 0 0 3 0.1608 glutathione conjugation reaction 18342 8 0 0 3 0.1608 protein prenylation 6241 8 0 0 3 0.1608 CTP biosynthesis 6228 8 0 0 3 0.1608 UTP biosynthesis 6183 8 0 0 3 0.1608 GTP biosynthesis 6040 8 0 0 3 0.1608 amino sugar metabolism 9451 8 0 0 3 0.1608 RNA modification 4550 8 0 0 3 0.1608 nucleoside-diphosphate kinase activity 16408 8 0 0 3 0.1608 C-acyltransferase activity 4402 8 0 0 3 0.1608 histone acetyltransferase activity 9220 8 0 0 3 0.1608 pyrimidine ribonucleotide biosynthesis 9218 8 0 0 3 0.1608 pyrimidine ribonucleotide metabolism 9209 8 0 0 3 0.1608 pyrimidine ribonucleoside triphosphate biosynthesis 9208 8 0 0 3 0.1608 pyrimidine ribonucleoside triphosphate metabolism 17018 8 0 0 3 0.1608 myosin phosphatase activity 8420 8 0 0 3 0.1608 CTD phosphatase activity 16568 42 0 0 11 0.1616 chromatin modification 8371 23 0 0 7 0.1668 obsolete 6950 337 0 0 51 0.1671 response to stress 747 15 0 0 5 0.1673 conjugation with cellular fusion 746 15 0 0 5 0.1673 conjugation 3931 15 0 0 5 0.1673 Rho small monomeric GTPase activity 9072 18 0 0 1 0.1708 aromatic amino acid family metabolism 16192 133 0 0 30 0.1714 vesicle-mediated transport 8652 33 0 0 9 0.1725 amino acid biosynthesis 8610 93 0 0 22 0.1727 lipid biosynthesis 9057 353 0 0 73 0.1766 macromolecule catabolism 8025 1 0 0 1 0.18 diazepam-binding inhibitor activity 15165 1 0 0 1 0.18 pyrimidine nucleotide sugar transporter activity 46208 1 0 0 1 0.18 spermine catabolism 46149 1 0 0 1 0.18 pigment catabolism 6965 1 0 0 1 0.18 anti-Gram-positive bacterial polypeptide induction 46033 1 0 0 1 0.18 AMP metabolism 46011 1 0 0 1 0.18 regulation of oskar mRNA translation 6802 1 0 0 1 0.18 catalase reaction 6688 1 0 0 1 0.18 glycosphingolipid biosynthesis 6687 1 0 0 1 0.18 glycosphingolipid metabolism 6683 1 0 0 1 0.18 galactosylceramide catabolism 6681 1 0 0 1 0.18 galactosylceramide metabolism 6679 1 0 0 1 0.18 glucosylceramide biosynthesis 6678 1 0 0 1 0.18 glucosylceramide metabolism 6655 1 0 0 1 0.18 phosphatidylglycerol biosynthesis 6624 1 0 0 1 0.18 vacuolar protein processing/maturation 6598 1 0 0 1 0.18 polyamine catabolism 1650 1 0 0 1 0.18 fibrillar center 6450 1 0 0 1 0.18 regulation of translational fidelity 6437 1 0 0 1 0.18 tyrosyl-tRNA aminoacylation 6430 1 0 0 1 0.18 lysyl-tRNA aminoacylation 6423 1 0 0 1 0.18 cysteinyl-tRNA aminoacylation 6388 1 0 0 1 0.18 tRNA splicing 6382 1 0 0 1 0.18 adenosine to inosine editing 18279 1 0 0 1 0.18 N-linked glycosylation via asparagine 18196 1 0 0 1 0.18 peptidyl-asparagine modification 6168 1 0 0 1 0.18 adenine salvage pathway 6167 1 0 0 1 0.18 AMP biosynthesis 6155 1 0 0 1 0.18 adenosine deaminase reaction 6129 1 0 0 1 0.18 protein-disulfide reduction 6048 1 0 0 1 0.18 UDP-N-acetylglucosamine biosynthesis 6047 1 0 0 1 0.18 UDP-N-acetylglucosamine metabolism 6031 1 0 0 1 0.18 chitin biosynthesis 6010 1 0 0 1 0.18 glucose 6-phosphate utilization 6008 1 0 0 1 0.18 glucose 1-phosphate utilization 9955 1 0 0 1 0.18 adaxial/abaxial pattern formation 9926 1 0 0 1 0.18 auxin polar transport 9914 1 0 0 1 0.18 hormone transport 9901 1 0 0 1 0.18 anther dehiscence 9900 1 0 0 1 0.18 dehiscence 9861 1 0 0 1 0.18 jasmonic acid/ethylene dependent systemic resistance 9832 1 0 0 1 0.18 cell wall biosynthesis (sensu Magnoliophyta) 4998 1 0 0 1 0.18 transferrin receptor activity 4990 1 0 0 1 0.18 oxytocin receptor activity 16923 1 0 0 1 0.18 ligand-dependent thyroid hormone receptor interactor activity 9789 1 0 0 1 0.18 positive regulation of abscisic acid mediated signaling 9787 1 0 0 1 0.18 regulation of abscisic acid mediated signaling 9738 1 0 0 1 0.18 abscisic acid mediated signaling 9737 1 0 0 1 0.18 response to abscisic acid stimulus 4883 1 0 0 1 0.18 glucocorticoid receptor activity 4831 1 0 0 1 0.18 tyrosine-tRNA ligase activity 4824 1 0 0 1 0.18 lysine-tRNA ligase activity 4817 1 0 0 1 0.18 cysteine-tRNA ligase activity 4816 1 0 0 1 0.18 asparagine-tRNA ligase activity 4807 1 0 0 1 0.18 triose-phosphate isomerase activity 9695 1 0 0 1 0.18 jasmonic acid biosynthesis 9694 1 0 0 1 0.18 jasmonic acid metabolism 9664 1 0 0 1 0.18 cell wall organization and biogenesis (sensu Magnoliophyta) 16724 1 0 0 1 0.18 "oxidoreductase activity, oxidizing metal ions, oxygen as acceptor" 16722 1 0 0 1 0.18 "oxidoreductase activity, oxidizing metal ions" 4729 1 0 0 1 0.18 protoporphyrinogen oxidase activity 4723 1 0 0 1 0.18 calcium-dependent protein serine/threonine phosphatase activity 9585 1 0 0 1 0.18 "red, far-red light phototransduction" 9584 1 0 0 1 0.18 perception of visible light 4681 1 0 0 1 0.18 casein kinase I activity 16635 1 0 0 1 0.18 "oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor" 4643 1 0 0 1 0.18 phosphoribosylaminoimidazole-carboxamide formyltransferase activity 4610 1 0 0 1 0.18 phosphoacetylglucosamine mutase activity 4582 1 0 0 1 0.18 dolichyl-phosphate beta-D-mannosyltransferase activity 4581 1 0 0 1 0.18 dolichyl-phosphate beta-glucosyltransferase activity 16510 1 0 0 1 0.18 short-chain enoyl-CoA hydratase activity 16508 1 0 0 1 0.18 long-chain enoyl-CoA hydratase activity 4506 1 0 0 1 0.18 squalene monooxygenase activity 4496 1 0 0 1 0.18 mevalonate kinase activity 4485 1 0 0 1 0.18 methylcrotonyl-CoA carboxylase activity 4462 1 0 0 1 0.18 lactoylglutathione lyase activity 4439 1 0 0 1 0.18 phosphatidylinositol-bisphosphatase activity 4419 1 0 0 1 0.18 hydroxymethylglutaryl-CoA lyase activity 4406 1 0 0 1 0.18 H3/H4 histone acetyltransferase activity 9272 1 0 0 1 0.18 cell wall biosynthesis (sensu Fungi) 30643 1 0 0 1 0.18 phosphate ion homeostasis 4363 1 0 0 1 0.18 glutathione synthase activity 4356 1 0 0 1 0.18 glutamate-ammonia ligase activity 4347 1 0 0 1 0.18 glucose-6-phosphate isomerase activity 4337 1 0 0 1 0.18 geranyltranstransferase activity 4336 1 0 0 1 0.18 galactosylceramidase activity 4322 1 0 0 1 0.18 ferroxidase activity 4310 1 0 0 1 0.18 farnesyl-diphosphate farnesyltransferase activity 42542 1 0 0 1 0.18 response to hydrogen peroxide 16285 1 0 0 1 0.18 cytosol alanyl aminopeptidase activity 30522 1 0 0 1 0.18 intracellular receptor-mediated signaling pathway 30520 1 0 0 1 0.18 estrogen receptor signaling pathway 30518 1 0 0 1 0.18 steroid hormone receptor signaling pathway 4250 1 0 0 1 0.18 aminopeptidase I activity 4231 1 0 0 1 0.18 insulysin activity 4217 1 0 0 1 0.18 cathepsin L activity 4215 1 0 0 1 0.18 cathepsin H activity 4213 1 0 0 1 0.18 cathepsin B activity 4201 1 0 0 1 0.18 caspase-1 activity 9061 1 0 0 1 0.18 anaerobic respiration 30481 1 0 0 1 0.18 septin ring (sensu Fungi) 30472 1 0 0 1 0.18 mitotic spindle assembly (sensu Fungi) 4192 1 0 0 1 0.18 cathepsin D activity 30447 1 0 0 1 0.18 filamentous growth 16138 1 0 0 1 0.18 glycoside biosynthesis 16137 1 0 0 1 0.18 glycoside metabolism 4145 1 0 0 1 0.18 diamine N-acetyltransferase activity 16082 1 0 0 1 0.18 synaptic vesicle priming 4096 1 0 0 1 0.18 catalase activity 4083 1 0 0 1 0.18 bisphosphoglycerate phosphatase activity 30338 1 0 0 1 0.18 CMP-N-acetylneuraminate monooxygenase activity 4072 1 0 0 1 0.18 aspartate kinase activity 30327 1 0 0 1 0.18 prenylated protein catabolism 30319 1 0 0 1 0.18 "di-, tri-valent inorganic anion homeostasis" 4056 1 0 0 1 0.18 argininosuccinate lyase activity 16028 1 0 0 1 0.18 rhabdomere 4033 1 0 0 1 0.18 aldo-keto reductase activity 4032 1 0 0 1 0.18 aldehyde reductase activity 4018 1 0 0 1 0.18 adenylosuccinate lyase activity 19894 1 0 0 1 0.18 kinesin binding 19829 1 0 0 1 0.18 cation-transporting ATPase activity 42167 1 0 0 1 0.18 heme catabolism 42147 1 0 0 1 0.18 retrograde (endosome to Golgi) transport 30161 1 0 0 1 0.18 calpain inhibitor activity 30149 1 0 0 1 0.18 sphingolipid catabolism 30127 1 0 0 1 0.18 COPII vesicle coat 19761 1 0 0 1 0.18 glucosinolate biosynthesis 19760 1 0 0 1 0.18 glucosinolate metabolism 19758 1 0 0 1 0.18 glycosinolate biosynthesis 19757 1 0 0 1 0.18 glycosinolate metabolism 19737 1 0 0 1 0.18 quinol:fumarate oxidoreductase activity 19722 1 0 0 1 0.18 calcium-mediated signaling 42078 1 0 0 1 0.18 germ-line stem cell renewal 42049 1 0 0 1 0.18 cell acyl-CoA homeostasis 30069 1 0 0 1 0.18 lysogeny 42035 1 0 0 1 0.18 regulation of cytokine biosynthesis 30041 1 0 0 1 0.18 actin filament polymerization 30002 1 0 0 1 0.18 anion homeostasis 45950 1 0 0 1 0.18 negative regulation of mitotic recombination 45910 1 0 0 1 0.18 negative regulation of DNA recombination 7603 1 0 0 1 0.18 "phototransduction, visible light" 45865 1 0 0 1 0.18 regulation of recombination within rDNA repeats 19377 1 0 0 1 0.18 glycolipid catabolism 19376 1 0 0 1 0.18 galactolipid catabolism 19374 1 0 0 1 0.18 galactolipid metabolism 7396 1 0 0 1 0.18 suture of dorsal opening 7318 1 0 0 1 0.18 pole plasm protein localization 7317 1 0 0 1 0.18 regulation of pole plasm oskar mRNA localization 7282 1 0 0 1 0.18 cystoblast cell division 45458 1 0 0 1 0.18 recombination within rDNA repeats 19198 1 0 0 1 0.18 transmembrane receptor protein phosphatase activity 45450 1 0 0 1 0.18 bicoid mRNA localization 19145 1 0 0 1 0.18 aminobutyraldehyde dehydrogenase activity 7120 1 0 0 1 0.18 axial budding 45324 1 0 0 1 0.18 late endosome to vacuole transport 19047 1 0 0 1 0.18 provirus integration 7042 1 0 0 1 0.18 lysosomal lumen acidification 7035 1 0 0 1 0.18 vacuolar acidification 19007 1 0 0 1 0.18 N-acetylneuraminic acid phosphate synthase activity 7009 1 0 0 1 0.18 plasma membrane organization and biogenesis 45283 1 0 0 1 0.18 fumarate reductase complex 45281 1 0 0 1 0.18 succinate dehydrogenase complex 45273 1 0 0 1 0.18 respiratory chain complex II 45257 1 0 0 1 0.18 succinate dehydrogenase complex (ubiquinone) 45242 1 0 0 1 0.18 isocitrate dehydrogenase complex (NAD+) 5962 1 0 0 1 0.18 isocitrate dehydrogenase complex (NAD+) (sensu Eukarya) 5955 1 0 0 1 0.18 calcineurin complex 5940 1 0 0 1 0.18 septin ring 5934 1 0 0 1 0.18 bud tip 45053 1 0 0 1 0.18 protein-Golgi retention 45034 1 0 0 1 0.18 neuroblast cell division 5833 1 0 0 1 0.18 hemoglobin complex 5788 1 0 0 1 0.18 endoplasmic reticulum lumen 5749 1 0 0 1 0.18 respiratory chain complex II (sensu Eukarya) 5742 1 0 0 1 0.18 mitochondrial outer membrane translocase complex 5701 1 0 0 1 0.18 polytene chromosome chromocenter 767 1 0 0 1 0.18 cellular morphogenesis during conjugation 754 1 0 0 1 0.18 adaptation to pheromone during conjugation with cellular fusion 753 1 0 0 1 0.18 cellular morphogenesis during conjugation with cellular fusion 750 1 0 0 1 0.18 signal transduction during conjugation with cellular fusion 5459 1 0 0 1 0.18 UDP-galactose transporter activity 321 1 0 0 1 0.18 re-entry into mitotic cell cycle after pheromone arrest 17166 1 0 0 1 0.18 vinculin binding 17145 1 0 0 1 0.18 stem cell renewal 17134 1 0 0 1 0.18 fibroblast growth factor binding 5153 1 0 0 1 0.18 interleukin-8 receptor binding 254 1 0 0 1 0.18 C-4 methyl sterol oxidase activity 224 1 0 0 1 0.18 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 215 1 0 0 1 0.18 tRNA 2'-phosphotransferase activity 5091 1 0 0 1 0.18 guanyl-nucleotide exchange factor adaptor activity 17057 1 0 0 1 0.18 6-phosphogluconolactonase activity 17052 1 0 0 1 0.18 insulin-like growth factor binding protein 17014 1 0 0 1 0.18 protein amino acid nitrosylation 5001 1 0 0 1 0.18 transmembrane receptor protein tyrosine phosphatase activity 8970 1 0 0 1 0.18 phospholipase A1 activity 184 1 0 0 1 0.18 "mRNA catabolism, nonsense-mediated" 182 1 0 0 1 0.18 ribosomal DNA (rDNA) binding 144 1 0 0 1 0.18 septin ring (sensu Saccharomyces) 104 1 0 0 1 0.18 succinate dehydrogenase activity 85 1 0 0 1 0.18 G2 phase of mitotic cell cycle 71 1 0 0 1 0.18 mitotic spindle assembly (sensu Saccharomyces) 30 1 0 0 1 0.18 mannosyltransferase activity 20 1 0 0 1 0.18 negative regulation of recombination within rDNA repeats 19 1 0 0 1 0.18 regulation of mitotic recombination 18 1 0 0 1 0.18 regulation of DNA recombination 3999 1 0 0 1 0.18 adenine phosphoribosyltransferase activity 3983 1 0 0 1 0.18 UTP-glucose-1-phosphate uridylyltransferase activity 3977 1 0 0 1 0.18 UDP-N-acetylglucosamine pyrophosphorylase activity 3975 1 0 0 1 0.18 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity 3958 1 0 0 1 0.18 NADPH-ferrihemoprotein reductase activity 3939 1 0 0 1 0.18 L-iditol 2-dehydrogenase activity 3937 1 0 0 1 0.18 IMP cyclohydrolase activity 3932 1 0 0 1 0.18 SAR small monomeric GTPase activity 3929 1 0 0 1 0.18 RAN small monomeric GTPase activity 3923 1 0 0 1 0.18 GPI-anchor transamidase activity 3835 1 0 0 1 0.18 "beta-galactosamide alpha-2,6-sialyltransferase activity" 3827 1 0 0 1 0.18 "alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" 3812 1 0 0 1 0.18 alternative-complement pathway C3/C5 convertase activity 8670 1 0 0 1 0.18 "2,4-dienoyl-CoA reductase (NADPH) activity" 8665 1 0 0 1 0.18 2'-phosphotransferase activity 8614 1 0 0 1 0.18 pyridoxine metabolism 8605 1 0 0 1 0.18 "protein kinase CK2, regulator activity" 3796 1 0 0 1 0.18 lysozyme activity 3788 1 0 0 1 0.18 actin monomer sequestering activity 3785 1 0 0 1 0.18 actin monomer binding 3784 1 0 0 1 0.18 barbed-end actin capping/severing activity 3730 1 0 0 1 0.18 mRNA 3' UTR binding 46831 1 0 0 1 0.18 regulation of RNA-nucleus export 8597 1 0 0 1 0.18 "calcium-dependent protein serine/threonine phosphatase, regulator activity" 15646 1 0 0 1 0.18 permease activity 8478 1 0 0 1 0.18 pyridoxal kinase activity 15563 1 0 0 1 0.18 uptake permease activity 46664 1 0 0 1 0.18 "dorsal closure, amnioserosa morphology change" 8379 1 0 0 1 0.18 thioredoxin peroxidase activity 8333 1 0 0 1 0.18 endosome to lysosome transport 8312 1 0 0 1 0.18 7S RNA binding 15482 1 0 0 1 0.18 voltage-dependent anion channel porin activity 15433 1 0 0 1 0.18 major histocompatibility peptide transporter activity 15427 1 0 0 1 0.18 ABC-type efflux porter activity 15406 1 0 0 1 0.18 ABC-type uptake permease activity 46521 1 0 0 1 0.18 sphingoid catabolism 46520 1 0 0 1 0.18 sphingoid biosynthesis 46514 1 0 0 1 0.18 ceramide catabolism 46513 1 0 0 1 0.18 ceramide biosynthesis 8250 1 0 0 1 0.18 oligosaccharyl transferase complex 46477 1 0 0 1 0.18 glycosylceramide catabolism 46476 1 0 0 1 0.18 glycosylceramide biosynthesis 46471 1 0 0 1 0.18 phosphatidylglycerol metabolism 8177 1 0 0 1 0.18 succinate dehydrogenase (ubiquinone) activity 8129 1 0 0 1 0.18 actinidain activity 8117 1 0 0 1 0.18 sphinganine-1-phosphate aldolase activity 8110 1 0 0 1 0.18 histidine aminotransferase activity 8090 1 0 0 1 0.18 retrograde axon cargo transport 8088 1 0 0 1 0.18 axon cargo transport 8064 1 0 0 1 0.18 regulation of actin polymerization and/or depolymerization 8051 1 0 0 1 0.18 farnesyl-diphosphate farnesyl transferase complex 6959 35 0 0 3 0.1861 humoral immune response 4702 35 0 0 3 0.1861 receptor signaling protein serine/threonine kinase activity 6892 16 0 0 5 0.1872 post-Golgi transport 6497 16 0 0 5 0.1872 protein lipidation 42158 16 0 0 5 0.1872 lipoprotein biosynthesis 4519 36 0 0 3 0.1886 endonuclease activity 7178 36 0 0 3 0.1886 transmembrane receptor protein serine/threonine kinase signaling pathway 5275 36 0 0 3 0.1886 amine/polyamine transporter activity 7010 200 0 0 43 0.1912 cytoskeleton organization and biogenesis 7283 50 0 0 5 0.1934 spermatogenesis 6694 37 0 0 10 0.1937 steroid biosynthesis 9611 82 0 0 10 0.1938 response to wounding 46872 532 0 0 107 0.1953 metal ion binding 6812 237 0 0 35 0.1974 cation transport 6928 126 0 0 17 0.1992 cell motility 8370 38 0 0 10 0.2013 obsolete 5871 182 0 0 26 0.2039 kinesin complex 6865 26 0 0 2 0.2085 amino acid transport 6954 70 0 0 8 0.2088 inflammatory response 45087 70 0 0 8 0.2088 innate immune response 3684 27 0 0 2 0.209 damaged DNA binding 6891 9 0 0 3 0.2105 intra-Golgi transport 6879 9 0 0 3 0.2105 iron ion homeostasis 6595 9 0 0 3 0.2105 polyamine metabolism 16868 9 0 0 3 0.2105 "intramolecular transferase activity, phosphotransferases" 7047 9 0 0 3 0.2105 cell wall organization and biogenesis 45229 9 0 0 3 0.2105 external encapsulating structure organization and biogenesis 5391 9 0 0 3 0.2105 sodium/potassium-exchanging ATPase activity 8361 9 0 0 3 0.2105 regulation of cell size 8318 9 0 0 3 0.2105 protein prenyltransferase activity 6897 53 0 0 13 0.2106 endocytosis 4386 53 0 0 13 0.2106 helicase activity 5520 17 0 0 5 0.2115 insulin-like growth factor binding 19199 54 0 0 6 0.2159 transmembrane receptor protein kinase activity 6672 5 0 0 2 0.2224 ceramide metabolism 6628 5 0 0 2 0.2224 mitochondrial translocation 6610 5 0 0 2 0.2224 ribosomal protein-nucleus import 6348 5 0 0 2 0.2224 chromatin silencing at telomere 6044 5 0 0 2 0.2224 N-acetylglucosamine metabolism 6041 5 0 0 2 0.2224 glucosamine metabolism 16865 5 0 0 2 0.2224 "intramolecular isomerase activity, other intramolecular oxidoreductases" 16806 5 0 0 2 0.2224 dipeptidyl-peptidase and tripeptidyl-peptidase activity 4784 5 0 0 2 0.2224 superoxide dismutase activity 16721 5 0 0 2 0.2224 "oxidoreductase activity, acting on superoxide radicals as acceptor" 16628 5 0 0 2 0.2224 "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" 4449 5 0 0 2 0.2224 isocitrate dehydrogenase (NAD+) activity 42434 5 0 0 2 0.2224 indole derivative metabolism 42430 5 0 0 2 0.2224 indole and derivative metabolism 4024 5 0 0 2 0.2224 "alcohol dehydrogenase activity, zinc-dependent" 19888 5 0 0 2 0.2224 protein phosphatase regulator activity 7568 5 0 0 2 0.2224 aging 19208 5 0 0 2 0.2224 phosphatase regulator activity 7121 5 0 0 2 0.2224 polar budding 7034 5 0 0 2 0.2224 vacuolar transport 7021 5 0 0 2 0.2224 tubulin folding 7020 5 0 0 2 0.2224 microtubule nucleation 5514 5 0 0 2 0.2224 calcium ion storage activity 5178 5 0 0 2 0.2224 integrin binding 5097 5 0 0 2 0.2224 Rab GTPase activator activity 172 5 0 0 2 0.2224 ribonuclease MRP complex 171 5 0 0 2 0.2224 ribonuclease MRP activity 15988 5 0 0 2 0.2224 "energy coupled proton transport, against the electrochemical gradient" 3926 5 0 0 2 0.2224 ARF small monomeric GTPase activity 8601 5 0 0 2 0.2224 "protein phosphatase type 2A, regulator activity" 8299 5 0 0 2 0.2224 isoprenoid biosynthesis 8415 57 0 0 14 0.2232 acyltransferase activity 4714 42 0 0 4 0.2236 transmembrane receptor protein tyrosine kinase activity 46148 18 0 0 1 0.2274 pigment biosynthesis 280 119 0 0 16 0.2282 nuclear division 6333 43 0 0 11 0.2289 chromatin assembly/disassembly 1654 19 0 0 1 0.2295 eye morphogenesis 6304 19 0 0 1 0.2295 DNA modification 16265 177 0 0 38 0.2337 death 15629 98 0 0 22 0.2356 actin cytoskeleton 4867 44 0 0 11 0.2365 serine protease inhibitor activity 902 44 0 0 11 0.2365 cellular morphogenesis 16747 59 0 0 14 0.2367 "transferase activity, transferring groups other than amino-acyl groups" 6289 20 0 0 1 0.2368 nucleotide-excision repair 4114 20 0 0 1 0.2368 "3',5'-cyclic-nucleotide phosphodiesterase activity" 8146 20 0 0 1 0.2368 sulfotransferase activity 8270 101 0 0 23 0.2388 zinc ion binding 15036 12 0 0 4 0.2472 disulfide oxidoreductase activity 6405 12 0 0 4 0.2472 RNA-nucleus export 9593 12 0 0 4 0.2472 perception of chemical substance 9161 12 0 0 4 0.2472 ribonucleoside monophosphate metabolism 16288 12 0 0 4 0.2472 cytokinesis 7606 12 0 0 4 0.2472 chemosensory perception 3925 63 0 0 15 0.2472 small monomeric GTPase activity 7029 21 0 0 6 0.2488 ER organization and biogenesis 45047 21 0 0 6 0.2488 protein-ER targeting 30695 106 0 0 14 0.2503 GTPase regulator activity 1501 47 0 0 5 0.2517 skeletal development 12501 162 0 0 35 0.254 programmed cell death 19935 34 0 0 3 0.2593 cyclic-nucleotide-mediated signaling 4197 49 0 0 12 0.2606 cysteine-type endopeptidase activity 6470 67 0 0 8 0.2616 protein amino acid dephosphorylation 16311 67 0 0 8 0.2616 dephosphorylation 5856 419 0 0 84 0.2641 cytoskeleton 6916 22 0 0 6 0.2649 anti-apoptosis 8219 170 0 0 36 0.267 cell death 6888 13 0 0 4 0.2693 ER to Golgi transport 9123 13 0 0 4 0.2693 nucleoside monophosphate metabolism 19748 13 0 0 4 0.2693 secondary metabolism 7266 13 0 0 4 0.2693 Rho protein signal transduction 5201 53 0 0 6 0.2797 extracellular matrix structural constituent 7264 95 0 0 21 0.2835 small GTPase mediated signal transduction 16627 23 0 0 6 0.2846 "oxidoreductase activity, acting on the CH-CH group of donors" 151 23 0 0 6 0.2846 ubiquitin ligase complex 45182 221 0 0 46 0.2848 translation regulator activity 6357 98 0 0 13 0.2881 regulation of transcription from Pol II promoter 45941 24 0 0 2 0.2918 positive regulation of transcription 5657 24 0 0 2 0.2918 replication fork 6821 39 0 0 4 0.2941 chloride transport 6957 6 0 0 2 0.2957 "complement activation, alternative pathway" 6899 6 0 0 2 0.2957 nonselective vesicle transport 6825 6 0 0 2 0.2957 copper ion transport 6804 6 0 0 2 0.2957 peroxidase reaction 6626 6 0 0 2 0.2957 protein-mitochondrial targeting 6613 6 0 0 2 0.2957 cotranslational membrane targeting 6537 6 0 0 2 0.2957 glutamate biosynthesis 6505 6 0 0 2 0.2957 GPI anchor metabolism 6308 6 0 0 2 0.2957 DNA catabolism 16861 6 0 0 2 0.2957 "intramolecular isomerase activity, interconverting aldoses and ketoses" 4727 6 0 0 2 0.2957 prenylated protein tyrosine phosphatase activity 9566 6 0 0 2 0.2957 fertilization 4372 6 0 0 2 0.2957 glycine hydroxymethyltransferase activity 9116 6 0 0 2 0.2957 nucleoside metabolism 30437 6 0 0 2 0.2957 sporulation (sensu Fungi) 42402 6 0 0 2 0.2957 biogenic amine catabolism 4022 6 0 0 2 0.2957 alcohol dehydrogenase activity 42219 6 0 0 2 0.2957 amino acid derivative catabolism 19865 6 0 0 2 0.2957 immunoglobulin binding 7338 6 0 0 2 0.2957 fertilization (sensu Animalia) 45595 6 0 0 2 0.2957 regulation of cell differentiation 7004 6 0 0 2 0.2957 telomerase-dependent telomere maintenance 5652 6 0 0 2 0.2957 nuclear lamina 5626 6 0 0 2 0.2957 insoluble fraction 776 6 0 0 2 0.2957 kinetochore 22 6 0 0 2 0.2957 mitotic spindle elongation 46527 6 0 0 2 0.2957 glucosyltransferase activity 46519 6 0 0 2 0.2957 sphingoid metabolism 8239 6 0 0 2 0.2957 dipeptidyl-peptidase activity 18193 14 0 0 4 0.297 peptidyl-amino acid modification 922 14 0 0 4 0.297 spindle pole 8026 40 0 0 10 0.2988 ATP dependent helicase activity 5923 26 0 0 7 0.3013 tight junction 5912 26 0 0 7 0.3013 adherens junction 5507 26 0 0 7 0.3013 copper ion binding 8203 26 0 0 7 0.3013 cholesterol metabolism 74 199 0 0 30 0.3033 regulation of cell cycle 15630 239 0 0 49 0.3038 microtubule cytoskeleton 4722 27 0 0 7 0.3118 protein serine/threonine phosphatase activity 16329 61 0 0 14 0.3151 apoptosis regulator activity 7276 84 0 0 11 0.3158 gametogenesis 1525 37 0 0 1 0.32 angiogenesis 4725 43 0 0 5 0.3252 protein tyrosine phosphatase activity 7292 28 0 0 7 0.3256 oogenesis 15074 2 0 0 1 0.3277 DNA integration 6999 2 0 0 1 0.3277 nuclear pore organization and biogenesis 6966 2 0 0 1 0.3277 antifungal humoral response (sensu Invertebrata) 6884 2 0 0 1 0.3277 regulation of cell volume 6659 2 0 0 1 0.3277 phosphatidylserine biosynthesis 6616 2 0 0 1 0.3277 "SRP-dependent cotranslational membrane targeting, translocation" 6609 2 0 0 1 0.3277 mRNA-binding (hnRNP) protein-nucleus import 6608 2 0 0 1 0.3277 snRNP protein-nucleus import 1738 2 0 0 1 0.3277 morphogenesis of a polarized epithelium 1736 2 0 0 1 0.3277 establishment of planar polarity 6552 2 0 0 1 0.3277 leucine catabolism 6551 2 0 0 1 0.3277 leucine metabolism 6510 2 0 0 1 0.3277 ATP-dependent proteolysis 6488 2 0 0 1 0.3277 dolichol-linked oligosaccharide biosynthesis 6475 2 0 0 1 0.3277 internal protein amino acid acetylation 6436 2 0 0 1 0.3277 tryptophanyl-tRNA aminoacylation 6422 2 0 0 1 0.3277 aspartyl-tRNA aminoacylation 6407 2 0 0 1 0.3277 rRNA-nucleus export 6370 2 0 0 1 0.3277 mRNA capping 6313 2 0 0 1 0.3277 DNA transposition 6177 2 0 0 1 0.3277 GMP biosynthesis 6166 2 0 0 1 0.3277 purine salvage 6102 2 0 0 1 0.3277 isocitrate metabolism 6054 2 0 0 1 0.3277 N-acetylneuraminate metabolism 18024 2 0 0 1 0.3277 histone-lysine N-methyltransferase activity 6030 2 0 0 1 0.3277 chitin metabolism 16978 2 0 0 1 0.3277 lipoate-protein ligase B activity 9755 2 0 0 1 0.3277 hormone mediated signaling 9733 2 0 0 1 0.3277 response to auxin stimulus 4862 2 0 0 1 0.3277 cAMP-dependent protein kinase inhibitor activity 4830 2 0 0 1 0.3277 tryptophan-tRNA ligase activity 4815 2 0 0 1 0.3277 aspartate-tRNA ligase activity 9618 2 0 0 1 0.3277 response to pathogenic bacteria 4781 2 0 0 1 0.3277 sulfate adenylyltransferase (ATP) activity 4779 2 0 0 1 0.3277 sulfate adenylyltransferase activity 4768 2 0 0 1 0.3277 stearoyl-CoA desaturase activity 16728 2 0 0 1 0.3277 "oxidoreductase activity, acting on CH2 groups, disulfide as acceptor" 16725 2 0 0 1 0.3277 "oxidoreductase activity, acting on CH2 groups" 4748 2 0 0 1 0.3277 ribonucleoside-diphosphate reductase activity 4743 2 0 0 1 0.3277 pyruvate kinase activity 4708 2 0 0 1 0.3277 MAP kinase kinase activity 16668 2 0 0 1 0.3277 "oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor" 16601 2 0 0 1 0.3277 RAC protein signal transduction 4619 2 0 0 1 0.3277 phosphoglycerate mutase activity 4618 2 0 0 1 0.3277 phosphoglycerate kinase activity 4614 2 0 0 1 0.3277 phosphoglucomutase activity 4605 2 0 0 1 0.3277 phosphatidate cytidylyltransferase activity 9452 2 0 0 1 0.3277 RNA capping 9415 2 0 0 1 0.3277 response to water 16571 2 0 0 1 0.3277 histone methylation 16553 2 0 0 1 0.3277 base conversion/substitution editing 4566 2 0 0 1 0.3277 beta-glucuronidase activity 4563 2 0 0 1 0.3277 beta-N-acetylhexosaminidase activity 16492 2 0 0 1 0.3277 "neurotensin receptor activity, G-protein coupled" 4441 2 0 0 1 0.3277 "inositol-1,4-bisphosphate 1-phosphatase activity" 16403 2 0 0 1 0.3277 dimethylargininase activity 9247 2 0 0 1 0.3277 glycolipid biosynthesis 4365 2 0 0 1 0.3277 glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity 4311 2 0 0 1 0.3277 farnesyltranstransferase activity 4301 2 0 0 1 0.3277 epoxide hydrolase activity 42552 2 0 0 1 0.3277 myelination 16279 2 0 0 1 0.3277 protein-lysine N-methyltransferase activity 16278 2 0 0 1 0.3277 lysine N-methyltransferase activity 16215 2 0 0 1 0.3277 CoA desaturase activity 30476 2 0 0 1 0.3277 spore wall assembly (sensu Fungi) 4148 2 0 0 1 0.3277 dihydrolipoamide dehydrogenase activity 4105 2 0 0 1 0.3277 choline-phosphate cytidylyltransferase activity 4082 2 0 0 1 0.3277 bisphosphoglycerate mutase activity 30336 2 0 0 1 0.3277 negative regulation of cell migration 30332 2 0 0 1 0.3277 cyclin binding 4074 2 0 0 1 0.3277 biliverdin reductase activity 4069 2 0 0 1 0.3277 aspartate aminotransferase activity 4055 2 0 0 1 0.3277 argininosuccinate synthase activity 30286 2 0 0 1 0.3277 dynein complex 42244 2 0 0 1 0.3277 spore wall assembly 19885 2 0 0 1 0.3277 "antigen processing, endogenous antigen via MHC class I" 19883 2 0 0 1 0.3277 "antigen presentation, endogenous antigen" 30175 2 0 0 1 0.3277 filopodium 42145 2 0 0 1 0.3277 homotypic vacuole fusion (non-autophagic) 42144 2 0 0 1 0.3277 vacuole fusion (non-autophagic) 30106 2 0 0 1 0.3277 MHC class I receptor activity 42067 2 0 0 1 0.3277 establishment of ommatidial polarity (sensu Drosophila) 30062 2 0 0 1 0.3277 TCA cycle enzyme complex (sensu Eukarya) 30027 2 0 0 1 0.3277 lamellipodium 7607 2 0 0 1 0.3277 taste 45806 2 0 0 1 0.3277 negative regulation of endocytosis 45792 2 0 0 1 0.3277 negative regulation of cell size 7405 2 0 0 1 0.3277 neuroblast proliferation 7349 2 0 0 1 0.3277 cellularization 7316 2 0 0 1 0.3277 pole plasm RNA localization 7315 2 0 0 1 0.3277 pole plasm assembly 19255 2 0 0 1 0.3277 glucose 1-phosphate metabolism 19202 2 0 0 1 0.3277 amino acid kinase activity 7213 2 0 0 1 0.3277 "acetyl choline receptor signaling, muscarinic pathway" 45451 2 0 0 1 0.3277 pole plasm oskar mRNA localization 7164 2 0 0 1 0.3277 establishment of tissue polarity 7152 2 0 0 1 0.3277 spore wall assembly (sensu Saccharomyces) 19094 2 0 0 1 0.3277 pole plasm mRNA localization 7096 2 0 0 1 0.3277 regulation of exit from mitosis 7022 2 0 0 1 0.3277 chaperonin-mediated tubulin folding 45239 2 0 0 1 0.3277 TCA cycle enzyme complex 45216 2 0 0 1 0.3277 intercellular junction assembly and/or maintenance 45179 2 0 0 1 0.3277 apical cortex 5971 2 0 0 1 0.3277 ribonucleoside-diphosphate reductase complex 5814 2 0 0 1 0.3277 centriole 5793 2 0 0 1 0.3277 ER-Golgi intermediate compartment 5790 2 0 0 1 0.3277 smooth endoplasmic reticulum 5765 2 0 0 1 0.3277 lysosomal membrane 5688 2 0 0 1 0.3277 snRNP U6 5666 2 0 0 1 0.3277 DNA-directed RNA polymerase III complex 5653 2 0 0 1 0.3277 perinuclear space 5594 2 0 0 1 0.3277 collagen type IX 5593 2 0 0 1 0.3277 facit collagen 5545 2 0 0 1 0.3277 phosphatidylinositol binding 5338 2 0 0 1 0.3277 nucleotide-sugar transporter activity 5229 2 0 0 1 0.3277 intracellular calcium activated chloride channel activity 211 2 0 0 1 0.3277 protein degradation tagging activity 17070 2 0 0 1 0.3277 U6 snRNA binding 17069 2 0 0 1 0.3277 snRNA binding 5086 2 0 0 1 0.3277 ARF guanyl-nucleotide exchange factor activity 5080 2 0 0 1 0.3277 protein kinase C binding 17040 2 0 0 1 0.3277 ceramidase activity 5037 2 0 0 1 0.3277 death receptor adaptor protein activity 8943 2 0 0 1 0.3277 glyceraldehyde 3-phosphate dehydrogenase activity 36 2 0 0 1 0.3277 acyl carrier activity 3987 2 0 0 1 0.3277 acetate-CoA ligase activity 3938 2 0 0 1 0.3277 IMP dehydrogenase activity 3857 2 0 0 1 0.3277 3-hydroxyacyl-CoA dehydrogenase activity 3841 2 0 0 1 0.3277 1-acylglycerol-3-phosphate O-acyltransferase activity 8638 2 0 0 1 0.3277 protein tagging activity 8631 2 0 0 1 0.3277 induction of apoptosis by oxidative stress 8625 2 0 0 1 0.3277 induction of apoptosis via death domain receptors 15780 2 0 0 1 0.3277 nucleotide-sugar transport 3789 2 0 0 1 0.3277 actin filament severing activity 8598 2 0 0 1 0.3277 "protein phosphatase type 1, catalyst activity" 15680 2 0 0 1 0.3277 intracellular copper ion transport 15671 2 0 0 1 0.3277 oxygen transport 3692 2 0 0 1 0.3277 left-handed Z-DNA binding 15669 2 0 0 1 0.3277 gas transport 46777 2 0 0 1 0.3277 autophosphorylation 8475 2 0 0 1 0.3277 procollagen-lysine 5-dioxygenase activity 8474 2 0 0 1 0.3277 palmitoyl-protein hydrolase activity 8340 2 0 0 1 0.3277 determination of adult life span 8143 2 0 0 1 0.3277 poly(A) binding 8142 2 0 0 1 0.3277 oxysterol binding 8120 2 0 0 1 0.3277 ceramide glucosyltransferase activity 8107 2 0 0 1 0.3277 galactoside 2-alpha-L-fucosyltransferase activity 46381 2 0 0 1 0.3277 CMP-N-acetylneuraminate metabolism 8097 2 0 0 1 0.3277 5S RNA binding 8053 2 0 0 1 0.3277 mitochondrial fusion 8044 2 0 0 1 0.3277 adult behavior (sensu Insecta) 9084 15 0 0 4 0.329 glutamine family amino acid biosynthesis 19200 15 0 0 4 0.329 carbohydrate kinase activity 123 15 0 0 4 0.329 histone acetyltransferase complex 8189 15 0 0 4 0.329 apoptosis inhibitor activity 6520 89 0 0 12 0.3303 amino acid metabolism 16746 66 0 0 15 0.3329 "transferase activity, transferring acyl groups" 6306 16 0 0 1 0.3337 DNA methylation 6305 16 0 0 1 0.3337 DNA alkylation 6073 16 0 0 1 0.3337 glucan metabolism 19992 16 0 0 1 0.3337 diacylglycerol binding 19842 16 0 0 1 0.3337 vitamin binding 5977 16 0 0 1 0.3337 glycogen metabolism 5478 16 0 0 1 0.3337 intracellular transporter activity 16327 67 0 0 15 0.3387 apicolateral plasma membrane 6836 17 0 0 1 0.3391 neurotransmitter transport 16831 17 0 0 1 0.3391 carboxy-lyase activity 30118 17 0 0 1 0.3391 clathrin coat 7444 17 0 0 1 0.3391 imaginal disc development 7423 17 0 0 1 0.3391 sensory organ development 7189 17 0 0 1 0.3391 "G-protein signaling, adenylate cyclase activating pathway" 5212 17 0 0 1 0.3391 structural constituent of eye lens 8138 17 0 0 1 0.3391 protein tyrosine/serine/threonine phosphatase activity 15294 17 0 0 1 0.3391 solute:cation symporter activity 6810 960 0 0 162 0.34 transport 19933 31 0 0 3 0.346 cAMP-mediated signaling 46903 31 0 0 3 0.346 secretion 4222 70 0 0 9 0.3468 metalloendopeptidase activity 279 126 0 0 18 0.3481 M phase 6915 159 0 0 33 0.3482 apoptosis 6730 18 0 0 5 0.3502 one-carbon compound metabolism 6403 18 0 0 5 0.3502 RNA localization 42157 18 0 0 5 0.3502 lipoprotein metabolism 6360 32 0 0 8 0.3526 transcription from Pol I promoter 1568 42 0 0 1 0.3546 blood vessel development 16798 50 0 0 6 0.355 "hydrolase activity, acting on glycosyl bonds" 6814 51 0 0 6 0.3582 sodium ion transport 30234 257 0 0 52 0.362 enzyme regulator activity 6612 19 0 0 5 0.3662 protein-membrane targeting 8237 105 0 0 15 0.3708 metallopeptidase activity 8369 78 0 0 17 0.3744 obsolete 16741 56 0 0 7 0.3813 "transferase activity, transferring one-carbon groups" 5488 3520 0 0 620 0.3851 binding 6807 20 0 0 5 0.3863 nitrogen metabolism 5254 20 0 0 5 0.3863 chloride channel activity 16042 37 0 0 4 0.3882 lipid catabolism 19932 37 0 0 4 0.3882 second-messenger-mediated signaling 30136 37 0 0 4 0.3882 clathrin-coated vesicle 4721 85 0 0 12 0.3963 protein phosphatase activity 16758 59 0 0 13 0.397 "transferase activity, transferring hexosyl groups" 16787 1008 0 0 191 0.3975 hydrolase activity 6839 10 0 0 3 0.4 mitochondrial transport 6695 10 0 0 3 0.4 cholesterol biosynthesis 9993 10 0 0 3 0.4 oogenesis (sensu Insecta) 16866 10 0 0 3 0.4 intramolecular transferase activity 9167 10 0 0 3 0.4 purine ribonucleoside monophosphate metabolism 9156 10 0 0 3 0.4 ribonucleoside monophosphate biosynthesis 9147 10 0 0 3 0.4 pyrimidine nucleoside triphosphate metabolism 9126 10 0 0 3 0.4 purine nucleoside monophosphate metabolism 8021 21 0 0 2 0.4053 synaptic vesicle 1503 21 0 0 2 0.4053 ossification 7622 21 0 0 2 0.4053 rhythmic behavior 45893 21 0 0 2 0.4053 "positive regulation of transcription, DNA-dependent" 7269 21 0 0 2 0.4053 neurotransmitter secretion 5976 21 0 0 2 0.4053 polysaccharide metabolism 16064 22 0 0 2 0.406 humoral defense mechanism (sensu Vertebrata) 3714 22 0 0 2 0.406 transcription co-repressor activity 46849 22 0 0 2 0.406 bone remodeling 8202 63 0 0 14 0.4087 steroid metabolism 87 91 0 0 13 0.411 M phase of mitotic cell cycle 42440 23 0 0 2 0.4113 pigment metabolism 7420 23 0 0 2 0.4113 brain development 48066 23 0 0 2 0.4113 pigmentation 7126 41 0 0 5 0.4176 meiosis 8565 131 0 0 27 0.4221 protein transporter activity 5194 66 0 0 9 0.4226 cell adhesion molecule activity 5524 880 0 0 167 0.423 ATP binding 9309 43 0 0 10 0.4235 amine biosynthesis 46914 177 0 0 36 0.4273 transition metal ion binding 4869 11 0 0 3 0.429 cysteine protease inhibitor activity 9124 11 0 0 3 0.429 nucleoside monophosphate biosynthesis 30468 11 0 0 3 0.429 establishment of cell polarity (sensu Fungi) 30467 11 0 0 3 0.429 establishment and/or maintenance of cell polarity (sensu Fungi) 19954 11 0 0 3 0.429 asexual reproduction 30012 11 0 0 3 0.429 establishment and/or maintenance of cell polarity (sensu Saccharomyces) 19201 11 0 0 3 0.429 nucleotide kinase activity 7114 11 0 0 3 0.429 budding 40008 11 0 0 3 0.429 regulation of growth 283 11 0 0 3 0.429 establishment of cell polarity (sensu Saccharomyces) 163 11 0 0 3 0.429 protein phosphatase type 1 activity 90 11 0 0 3 0.429 mitotic anaphase 79 11 0 0 3 0.429 regulation of CDK activity 3724 11 0 0 3 0.429 RNA helicase activity 6913 44 0 0 10 0.4298 nucleocytoplasmic transport 16779 44 0 0 10 0.4298 nucleotidyltransferase activity 30054 69 0 0 15 0.4303 cell junction 19205 25 0 0 6 0.4336 "nucleobase, nucleoside, nucleotide kinase activity" 5496 25 0 0 6 0.4336 steroid binding 5253 25 0 0 6 0.4336 anion channel activity 4009 45 0 0 10 0.4381 ATP-binding cassette (ABC) transporter activity 5539 46 0 0 6 0.4467 glycosaminoglycan binding 8022 3 0 0 1 0.4488 protein C-terminus binding 15030 3 0 0 1 0.4488 Cajal body 6963 3 0 0 1 0.4488 antibacterial polypeptide induction 46139 3 0 0 1 0.4488 coenzymes and prosthetic group catabolism 6896 3 0 0 1 0.4488 Golgi to vacuole transport 6787 3 0 0 1 0.4488 porphyrin catabolism 6607 3 0 0 1 0.4488 NLS-bearing substrate-nucleus import 1725 3 0 0 1 0.4488 stress fibers 1708 3 0 0 1 0.4488 cell fate specification 1658 3 0 0 1 0.4488 ureteric bud branching 6469 3 0 0 1 0.4488 negative regulation of protein kinase activity 6462 3 0 0 1 0.4488 "protein complex assembly, multichaperone pathway" 6409 3 0 0 1 0.4488 tRNA-nucleus export 6368 3 0 0 1 0.4488 RNA elongation from Pol II promoter 6301 3 0 0 1 0.4488 postreplication repair 9933 3 0 0 1 0.4488 meristem organization 9826 3 0 0 1 0.4488 cell elongation 9825 3 0 0 1 0.4488 cell expansion 16979 3 0 0 1 0.4488 lipoate-protein ligase activity 16880 3 0 0 1 0.4488 acid-ammonia (or amide) ligase activity 16878 3 0 0 1 0.4488 acid-thiol ligase activity 4864 3 0 0 1 0.4488 protein phosphatase inhibitor activity 16839 3 0 0 1 0.4488 other carbon-oxygen lyase activity 20037 3 0 0 1 0.4488 heme binding 4749 3 0 0 1 0.4488 ribose-phosphate pyrophosphokinase activity 4739 3 0 0 1 0.4488 pyruvate dehydrogenase (lipoamide) activity 4738 3 0 0 1 0.4488 pyruvate dehydrogenase activity 4715 3 0 0 1 0.4488 non-membrane spanning protein tyrosine kinase activity 4682 3 0 0 1 0.4488 protein kinase CK2 activity 4652 3 0 0 1 0.4488 polynucleotide adenylyltransferase activity 4634 3 0 0 1 0.4488 phosphopyruvate hydratase activity 4622 3 0 0 1 0.4488 lysophospholipase activity 9437 3 0 0 1 0.4488 carnitine metabolism 9401 3 0 0 1 0.4488 phosphoenolpyruvate-dependent sugar phosphotransferase system 4596 3 0 0 1 0.4488 peptide alpha-N-acetyltransferase activity 16547 3 0 0 1 0.4488 RNA editing 4559 3 0 0 1 0.4488 alpha-mannosidase activity 9374 3 0 0 1 0.4488 biotin binding 16421 3 0 0 1 0.4488 CoA carboxylase activity 16411 3 0 0 1 0.4488 acylglycerol O-acyltransferase activity 16405 3 0 0 1 0.4488 CoA-ligase activity 16335 3 0 0 1 0.4488 morphogenesis of larval imaginal disc epithelium 30612 3 0 0 1 0.4488 arsenate reductase (thioredoxin) activity 16312 3 0 0 1 0.4488 inositol bisphosphate phosphatase activity 4332 3 0 0 1 0.4488 fructose-bisphosphate aldolase activity 4300 3 0 0 1 0.4488 enoyl-CoA hydratase activity 16211 3 0 0 1 0.4488 ammonia ligase activity 9083 3 0 0 1 0.4488 branched chain family amino acid catabolism 30480 3 0 0 1 0.4488 contractile ring (sensu Fungi) 30471 3 0 0 1 0.4488 spindle pole body and microtubule cycle (sensu Fungi) 42424 3 0 0 1 0.4488 catecholamine catabolism 42420 3 0 0 1 0.4488 dopamine catabolism 4084 3 0 0 1 0.4488 branched-chain amino acid aminotransferase activity 4062 3 0 0 1 0.4488 aryl sulfotransferase activity 4060 3 0 0 1 0.4488 arylamine N-acetyltransferase activity 16032 3 0 0 1 0.4488 viral life cycle 30228 3 0 0 1 0.4488 lipoprotein receptor activity 19882 3 0 0 1 0.4488 antigen presentation 30169 3 0 0 1 0.4488 low-density lipoprotein binding 30148 3 0 0 1 0.4488 sphingolipid biosynthesis 19732 3 0 0 1 0.4488 antifungal humoral response 42089 3 0 0 1 0.4488 cytokine biosynthesis 42052 3 0 0 1 0.4488 rhabdomere development 30073 3 0 0 1 0.4488 insulin secretion 30072 3 0 0 1 0.4488 peptide hormone secretion 30014 3 0 0 1 0.4488 CCR4-NOT complex 7560 3 0 0 1 0.4488 imaginal disc morphogenesis 19238 3 0 0 1 0.4488 cyclohydrolase activity 7157 3 0 0 1 0.4488 heterophilic cell adhesion 7102 3 0 0 1 0.4488 spindle pole body and microtubule cycle (sensu Saccharomyces) 7097 3 0 0 1 0.4488 nuclear migration 7000 3 0 0 1 0.4488 nucleolus organization and biogenesis 5956 3 0 0 1 0.4488 protein kinase CK2 complex 5914 3 0 0 1 0.4488 spot adherens junction 5826 3 0 0 1 0.4488 contractile ring 5795 3 0 0 1 0.4488 Golgi stack 5700 3 0 0 1 0.4488 polytene chromosome 5684 3 0 0 1 0.4488 major (U2-dependent) spliceosome 5678 3 0 0 1 0.4488 chromatin assembly complex 5675 3 0 0 1 0.4488 transcription factor TFIIH complex 5375 3 0 0 1 0.4488 copper ion transporter activity 17072 3 0 0 1 0.4488 tubulin-specific chaperone activity 5094 3 0 0 1 0.4488 Rho GDP-dissociation inhibitor activity 5041 3 0 0 1 0.4488 low-density lipoprotein receptor activity 8900 3 0 0 1 0.4488 hydrogen/potassium-exchanging ATPase activity 183 3 0 0 1 0.4488 chromatin silencing at ribosomal DNA (rDNA) 159 3 0 0 1 0.4488 protein phosphatase type 2A complex 142 3 0 0 1 0.4488 contractile ring (sensu Saccharomyces) 62 3 0 0 1 0.4488 acyl-CoA binding 15 3 0 0 1 0.4488 phosphopyruvate hydratase complex 15923 3 0 0 1 0.4488 mannosidase activity 3917 3 0 0 1 0.4488 DNA topoisomerase type I activity 3906 3 0 0 1 0.4488 DNA-(apurinic or apyrimidinic site) lyase activity 46906 3 0 0 1 0.4488 tetrapyrrole binding 3797 3 0 0 1 0.4488 antibacterial peptide activity 3727 3 0 0 1 0.4488 single-stranded RNA binding 3726 3 0 0 1 0.4488 double-stranded RNA adenosine deaminase activity 46879 3 0 0 1 0.4488 hormone secretion 46822 3 0 0 1 0.4488 regulation of nucleocytoplasmic transport 8535 3 0 0 1 0.4488 cytochrome c oxidase biogenesis 46620 3 0 0 1 0.4488 regulation of organ size 8215 3 0 0 1 0.4488 spermine metabolism 46466 3 0 0 1 0.4488 membrane lipid catabolism 8171 3 0 0 1 0.4488 O-methyltransferase activity 8105 3 0 0 1 0.4488 asymmetric protein localization 8073 3 0 0 1 0.4488 ornithine decarboxylase inhibitor activity 6917 26 0 0 6 0.4496 induction of apoptosis 12502 26 0 0 6 0.4496 induction of programmed cell death 8235 26 0 0 6 0.4496 metalloexopeptidase activity 30554 888 0 0 168 0.4525 adenyl nucleotide binding 30010 12 0 0 3 0.4625 establishment of cell polarity 19439 12 0 0 3 0.4625 aromatic compound catabolism 7088 12 0 0 3 0.4625 regulation of mitosis 8080 12 0 0 3 0.4625 N-acetyltransferase activity 15171 29 0 0 3 0.4645 amino acid transporter activity 5794 165 0 0 33 0.474 Golgi apparatus 8168 54 0 0 7 0.4753 methyltransferase activity 3927 31 0 0 7 0.4839 heterotrimeric G-protein GTPase activity 6968 13 0 0 1 0.4854 cellular defense response 9952 13 0 0 1 0.4854 anterior/posterior pattern formation 4860 13 0 0 1 0.4854 protein kinase inhibitor activity 30551 13 0 0 1 0.4854 cyclic nucleotide binding 4180 13 0 0 1 0.4854 carboxypeptidase activity 7128 13 0 0 1 0.4854 meiotic prophase I 5184 13 0 0 1 0.4854 neuropeptide hormone activity 5066 13 0 0 1 0.4854 transmembrane receptor protein tyrosine kinase signaling protein activity 8374 13 0 0 1 0.4854 O-acyltransferase activity 15370 13 0 0 1 0.4854 solute:sodium symporter activity 7067 88 0 0 13 0.487 mitosis 6937 14 0 0 1 0.4878 regulation of muscle contraction 6401 14 0 0 1 0.4878 RNA catabolism 30326 14 0 0 1 0.4878 limb morphogenesis 7626 14 0 0 1 0.4878 locomotory behavior 7452 14 0 0 1 0.4878 imaginal disc metamorphosis 19210 14 0 0 1 0.4878 kinase inhibitor activity 5921 14 0 0 1 0.4878 gap junction 8284 14 0 0 1 0.4878 positive regulation of cell proliferation 16526 15 0 0 1 0.4965 "G-protein coupled receptor activity, unknown ligand" 42398 15 0 0 1 0.4965 amino acid derivative biosynthesis 30125 15 0 0 1 0.4965 clathrin vesicle coat 7127 15 0 0 1 0.4965 meiosis I 5605 15 0 0 1 0.4965 basal lamina 46456 15 0 0 1 0.4965 eicosanoid biosynthesis 45202 33 0 0 4 0.4981 synaptic junction 9792 34 0 0 4 0.5007 embryonic development (sensu Animalia) 7229 35 0 0 8 0.5059 integrin-mediated signaling pathway 8234 62 0 0 13 0.5088 cysteine-type peptidase activity 6650 16 0 0 4 0.5105 glycerophospholipid metabolism 86 17 0 0 4 0.5287 G2/M transition of mitotic cell cycle 8632 17 0 0 4 0.5287 apoptotic program 4497 38 0 0 5 0.5304 monooxygenase activity 16053 39 0 0 5 0.5311 organic acid biosynthesis 7409 39 0 0 5 0.5311 axonogenesis 46394 39 0 0 5 0.5311 carboxylic acid biosynthesis 287 71 0 0 15 0.5335 magnesium ion binding 16051 41 0 0 9 0.5393 carbohydrate biosynthesis 19887 41 0 0 9 0.5393 protein kinase regulator activity 46209 4 0 0 1 0.5481 nitric oxide metabolism 6914 4 0 0 1 0.5481 autophagy 6895 4 0 0 1 0.5481 Golgi to endosome transport 6809 4 0 0 1 0.5481 nitric oxide biosynthesis 6791 4 0 0 1 0.5481 sulfur utilization 6768 4 0 0 1 0.5481 biotin metabolism 6743 4 0 0 1 0.5481 ubiquinone metabolism 6596 4 0 0 1 0.5481 polyamine biosynthesis 6527 4 0 0 1 0.5481 arginine catabolism 1678 4 0 0 1 0.5481 cell glucose homeostasis 1603 4 0 0 1 0.5481 vasopressin-like receptor activity 6408 4 0 0 1 0.5481 snRNA-nucleus export 6144 4 0 0 1 0.5481 purine base metabolism 9909 4 0 0 1 0.5481 regulation of flower development 16885 4 0 0 1 0.5481 "ligase activity, forming carbon-carbon bonds" 4843 4 0 0 1 0.5481 ubiquitin-specific protease activity 16778 4 0 0 1 0.5481 diphosphotransferase activity 4712 4 0 0 1 0.5481 protein threonine/tyrosine kinase activity 4689 4 0 0 1 0.5481 phosphorylase kinase activity 4549 4 0 0 1 0.5481 tRNA-specific ribonuclease activity 4526 4 0 0 1 0.5481 ribonuclease P activity 42742 4 0 0 1 0.5481 defense response to bacteria 4467 4 0 0 1 0.5481 long-chain-fatty-acid-CoA-ligase activity 30611 4 0 0 1 0.5481 arsenate reductase activity 42593 4 0 0 1 0.5481 glucose homeostasis 42577 4 0 0 1 0.5481 lipid phosphatase activity 42551 4 0 0 1 0.5481 nerve maturation 30515 4 0 0 1 0.5481 snoRNA binding 9082 4 0 0 1 0.5481 branched chain family amino acid biosynthesis 16080 4 0 0 1 0.5481 synaptic vesicle targeting 30333 4 0 0 1 0.5481 antigen processing 30317 4 0 0 1 0.5481 sperm motility 30312 4 0 0 1 0.5481 external encapsulating structure 4004 4 0 0 1 0.5481 ATP dependent RNA helicase activity 42107 4 0 0 1 0.5481 cytokine metabolism 30111 4 0 0 1 0.5481 regulation of Wnt receptor signaling pathway 19731 4 0 0 1 0.5481 antibacterial humoral response 30098 4 0 0 1 0.5481 lymphocytic blood cell differentiation 45859 4 0 0 1 0.5481 regulation of protein kinase activity 7400 4 0 0 1 0.5481 neuroblast cell fate determination 7314 4 0 0 1 0.5481 oocyte anterior/posterior axis determination 19221 4 0 0 1 0.5481 cytokine and chemokine mediated signaling pathway 19217 4 0 0 1 0.5481 regulation of fatty acid metabolism 19212 4 0 0 1 0.5481 phosphatase inhibitor activity 45444 4 0 0 1 0.5481 adipocyte differentiation 7119 4 0 0 1 0.5481 isotropic bud growth 7118 4 0 0 1 0.5481 apical bud growth 7094 4 0 0 1 0.5481 mitotic spindle checkpoint 2011 4 0 0 1 0.5481 morphogenesis of an epithelial sheet 45177 4 0 0 1 0.5481 apical part of cell 5964 4 0 0 1 0.5481 phosphorylase kinase complex 5937 4 0 0 1 0.5481 shmoo tip 5936 4 0 0 1 0.5481 shmoo 5798 4 0 0 1 0.5481 Golgi vesicle 5770 4 0 0 1 0.5481 late endosome 5618 4 0 0 1 0.5481 cell wall 5528 4 0 0 1 0.5481 FK506 binding 5527 4 0 0 1 0.5481 macrolide binding 5388 4 0 0 1 0.5481 calcium-transporting ATPase activity 17124 4 0 0 1 0.5481 SH3-domain binding 5006 4 0 0 1 0.5481 epidermal growth factor receptor activity 5000 4 0 0 1 0.5481 vasopressin receptor activity 145 4 0 0 1 0.5481 exocyst 118 4 0 0 1 0.5481 histone deacetylase complex 109 4 0 0 1 0.5481 nucleotide excision repair complex 103 4 0 0 1 0.5481 sulfate assimilation 60 4 0 0 1 0.5481 "protein-nucleus import, translocation" 50 4 0 0 1 0.5481 urea cycle 3988 4 0 0 1 0.5481 acetyl-CoA C-acyltransferase activity 3847 4 0 0 1 0.5481 2-acetyl-1-alkylglycerophosphocholine esterase activity 3810 4 0 0 1 0.5481 protein-glutamine gamma-glutamyltransferase activity 8635 4 0 0 1 0.5481 caspase activation via cytochrome c 8629 4 0 0 1 0.5481 induction of apoptosis by intracellular signals 8366 4 0 0 1 0.5481 nerve ensheathment 15485 4 0 0 1 0.5481 cholesterol binding 8298 4 0 0 1 0.5481 "mRNA localization, intracellular" 8278 4 0 0 1 0.5481 cohesin complex 8191 4 0 0 1 0.5481 metalloendopeptidase inhibitor activity 8186 4 0 0 1 0.5481 RNA dependent ATPase activity 8144 4 0 0 1 0.5481 drug binding 8092 173 0 0 34 0.5482 cytoskeletal protein binding 9791 19 0 0 2 0.5559 post-embryonic development 45944 19 0 0 2 0.5559 positive regulation of transcription from Pol II promoter 7623 19 0 0 2 0.5559 circadian rhythm 8094 19 0 0 2 0.5559 DNA dependent ATPase activity 6631 79 0 0 16 0.5582 fatty acid metabolism 5096 45 0 0 6 0.5587 GTPase activator activity 6956 20 0 0 2 0.5591 complement activation 6112 20 0 0 2 0.5591 energy reserve metabolism 4540 20 0 0 2 0.5591 ribonuclease activity 45165 20 0 0 2 0.5591 cell fate commitment 5875 193 0 0 31 0.568 microtubule associated complex 16829 86 0 0 13 0.5726 lyase activity 6643 49 0 0 7 0.5799 membrane lipid metabolism 5789 23 0 0 5 0.5903 endoplasmic reticulum membrane 8233 309 0 0 59 0.596 peptidase activity 16789 54 0 0 11 0.5969 carboxylic ester hydrolase activity 16702 24 0 0 3 0.6035 "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" 16701 24 0 0 3 0.6035 "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" 5319 24 0 0 3 0.6035 lipid transporter activity 5279 24 0 0 3 0.6035 amino acid-polyamine transporter activity 75 24 0 0 3 0.6035 cell cycle checkpoint 15203 24 0 0 3 0.6035 polyamine transporter activity 42445 26 0 0 3 0.6074 hormone metabolism 42221 26 0 0 3 0.6074 response to chemical substance 16876 27 0 0 6 0.6137 "ligase activity, forming aminoacyl-tRNA and related compounds" 16875 27 0 0 6 0.6137 "ligase activity, forming carbon-oxygen bonds" 4812 27 0 0 6 0.6137 tRNA ligase activity 4620 27 0 0 6 0.6137 phospholipase activity 8452 27 0 0 6 0.6137 RNA ligase activity 6720 7 0 0 2 0.6168 isoprenoid metabolism 6526 7 0 0 2 0.6168 arginine biosynthesis 6471 7 0 0 2 0.6168 protein amino acid ADP-ribosylation 1508 7 0 0 2 0.6168 regulation of action potential 6302 7 0 0 2 0.6168 double-strand break repair 16840 7 0 0 2 0.6168 carbon-nitrogen lyase activity 9617 7 0 0 2 0.6168 response to bacteria 16567 7 0 0 2 0.6168 protein ubiquitination 9225 7 0 0 2 0.6168 nucleotide-sugar metabolism 9081 7 0 0 2 0.6168 branched chain family amino acid metabolism 30483 7 0 0 2 0.6168 site of polarized growth (sensu Fungi) 30435 7 0 0 2 0.6168 sporulation 30427 7 0 0 2 0.6168 site of polarized growth 4005 7 0 0 2 0.6168 plasma membrane cation-transporting ATPase 7091 7 0 0 2 0.6168 mitotic metaphase/anaphase transition 2168 7 0 0 2 0.6168 larval development (sensu Insecta) 45121 7 0 0 2 0.6168 lipid raft 5769 7 0 0 2 0.6168 early endosome 5680 7 0 0 2 0.6168 anaphase-promoting complex 5637 7 0 0 2 0.6168 nuclear inner membrane 775 7 0 0 2 0.6168 "chromosome, pericentric region" 726 7 0 0 2 0.6168 non-recombinational repair 324 7 0 0 2 0.6168 vacuole (sensu Fungi) 322 7 0 0 2 0.6168 storage vacuole 134 7 0 0 2 0.6168 site of polarized growth (sensu Saccharomyces) 70 7 0 0 2 0.6168 mitotic chromosome segregation 8603 7 0 0 2 0.6168 "cAMP-dependent protein kinase, regulator activity" 3795 7 0 0 2 0.6168 antimicrobial peptide activity 3782 7 0 0 2 0.6168 F-actin capping activity 8033 7 0 0 2 0.6168 tRNA processing 5762 28 0 0 6 0.6224 mitochondrial large ribosomal subunit 5624 263 0 0 44 0.6238 membrane fraction 16564 29 0 0 6 0.6332 transcriptional repressor activity 5694 122 0 0 24 0.6342 chromosome 6869 30 0 0 4 0.6381 lipid transport 30145 30 0 0 4 0.6381 manganese ion binding 122 30 0 0 4 0.6381 negative regulation of transcription from Pol II promoter 7422 31 0 0 4 0.6394 peripheral nervous system development 7411 31 0 0 4 0.6394 axon guidance 6801 8 0 0 2 0.641 superoxide metabolism 6693 8 0 0 2 0.641 prostaglandin metabolism 6692 8 0 0 2 0.641 prostanoid metabolism 6536 8 0 0 2 0.641 glutamate metabolism 6525 8 0 0 2 0.641 arginine metabolism 9636 8 0 0 2 0.641 response to toxin 16775 8 0 0 2 0.641 "phosphotransferase activity, nitrogenous group as acceptor" 9168 8 0 0 2 0.641 purine ribonucleoside monophosphate biosynthesis 9127 8 0 0 2 0.641 purine nucleoside monophosphate biosynthesis 16079 8 0 0 2 0.641 synaptic vesicle exocytosis 4003 8 0 0 2 0.641 ATP dependent DNA helicase activity 30182 8 0 0 2 0.641 neuron differentiation 30100 8 0 0 2 0.641 regulation of endocytosis 152 8 0 0 2 0.641 nuclear ubiquitin ligase complex 51 8 0 0 2 0.641 urea cycle intermediate metabolism 3697 8 0 0 2 0.641 single-stranded DNA binding 8286 8 0 0 2 0.641 insulin receptor signaling pathway 8154 8 0 0 2 0.641 actin polymerization and/or depolymerization 8054 8 0 0 2 0.641 cyclin catabolism 40029 32 0 0 4 0.643 "regulation of gene expression, epigenetic" 228 32 0 0 4 0.643 nuclear chromosome 16591 34 0 0 7 0.6562 "DNA-directed RNA polymerase II, holoenzyme" 8201 35 0 0 5 0.6653 heparin binding 6826 9 0 0 2 0.6688 iron ion transport 6406 9 0 0 2 0.6688 mRNA-nucleus export 6265 9 0 0 2 0.6688 DNA topological change 16873 9 0 0 2 0.6688 other isomerase activity 16811 9 0 0 2 0.6688 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" 16718 9 0 0 2 0.6688 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous" 4691 9 0 0 2 0.6688 cAMP-dependent protein kinase activity 4690 9 0 0 2 0.6688 cyclic-nucleotide dependent protein kinase activity 16604 9 0 0 2 0.6688 nuclear body 30534 9 0 0 2 0.6688 adult behavior 30532 9 0 0 2 0.6688 small nuclear ribonucleoprotein complex 16044 9 0 0 2 0.6688 membrane organization and biogenesis 30141 9 0 0 2 0.6688 secretory granule 5048 9 0 0 2 0.6688 signal sequence binding 3916 9 0 0 2 0.6688 DNA topoisomerase activity 8360 9 0 0 2 0.6688 regulation of cell shape 15450 9 0 0 2 0.6688 protein translocase activity 6790 39 0 0 8 0.6759 sulfur metabolism 30135 41 0 0 6 0.6867 coated vesicle 6665 10 0 0 2 0.6983 sphingolipid metabolism 16755 10 0 0 2 0.6983 "transferase activity, transferring amino-acyl groups" 4198 10 0 0 2 0.6983 calpain activity 4182 10 0 0 2 0.6983 carboxypeptidase A activity 790 10 0 0 2 0.6983 nuclear chromatin 723 10 0 0 2 0.6983 telomere maintenance 114 10 0 0 2 0.6983 G1-specific transcription in mitotic cell cycle 3930 10 0 0 2 0.6983 RAS small monomeric GTPase activity 8417 10 0 0 2 0.6983 fucosyltransferase activity 5634 1455 0 0 267 0.6991 nucleus 6783 11 0 0 1 0.701 heme biosynthesis 6779 11 0 0 1 0.701 porphyrin biosynthesis 1656 11 0 0 1 0.701 metanephros development 16764 11 0 0 1 0.701 "transferase activity, transferring other glycosyl groups" 4407 11 0 0 1 0.701 histone deacetylase activity 30324 11 0 0 1 0.701 lung development 30323 11 0 0 1 0.701 respiratory tube development 42133 11 0 0 1 0.701 neurotransmitter metabolism 30004 11 0 0 1 0.701 monovalent inorganic cation homeostasis 7456 11 0 0 1 0.701 eye morphogenesis (sensu Drosophila) 19239 11 0 0 1 0.701 deaminase activity 5913 11 0 0 1 0.701 cell-cell adherens junction 5540 11 0 0 1 0.701 hyaluronic acid binding 5247 11 0 0 1 0.701 voltage-gated chloride channel activity 271 11 0 0 1 0.701 polysaccharide biosynthesis 8373 11 0 0 1 0.701 sialyltransferase activity 8104 11 0 0 1 0.701 protein localization 8067 11 0 0 1 0.701 "metabotropic glutamate, GABA-B-like receptor activity" 6958 12 0 0 1 0.7058 "complement activation, classical pathway" 1655 12 0 0 1 0.7058 urogenital system development 6402 12 0 0 1 0.7058 mRNA catabolism 9798 12 0 0 1 0.7058 axis specification 16883 12 0 0 1 0.7058 other carbon-nitrogen ligase activity 4707 12 0 0 1 0.7058 MAP kinase activity 4521 12 0 0 1 0.7058 endoribonuclease activity 7144 12 0 0 1 0.7058 female meiosis I 7131 12 0 0 1 0.7058 meiotic recombination 8170 12 0 0 1 0.7058 N-methyltransferase activity 3 112 0 0 18 0.7096 reproduction 6342 13 0 0 3 0.715 chromatin silencing 4623 13 0 0 3 0.715 phospholipase A2 activity 16440 13 0 0 3 0.715 transcriptional gene silencing 16197 13 0 0 3 0.715 endosome transport 45814 13 0 0 3 0.715 "negative regulation of gene expression, epigenetic" 16585 14 0 0 3 0.7274 chromatin remodeling complex 5351 14 0 0 3 0.7274 sugar porter activity 3674 5958 0 0 1076 0.7417 molecular_function 6221 15 0 0 3 0.7421 pyrimidine nucleotide biosynthesis 6220 15 0 0 3 0.7421 pyrimidine nucleotide metabolism 16410 15 0 0 3 0.7421 N-acyltransferase activity 7032 15 0 0 3 0.7421 endosome organization and biogenesis 8287 15 0 0 3 0.7421 protein serine/threonine phosphatase complex 9628 145 0 0 24 0.743 response to abiotic stimulus 16477 63 0 0 10 0.7441 cell migration 15672 153 0 0 29 0.7496 monovalent inorganic cation transport 30120 16 0 0 2 0.7522 vesicle coat 7602 17 0 0 2 0.7532 phototransduction 7265 17 0 0 2 0.7532 RAS protein signal transduction 7200 17 0 0 2 0.7532 "G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" 7143 17 0 0 2 0.7532 female meiosis 2165 17 0 0 2 0.7532 larval/pupal development (sensu Insecta) 2164 17 0 0 2 0.7532 larval development 3811 17 0 0 2 0.7532 complement activity 8047 69 0 0 11 0.754 enzyme activator activity 5083 70 0 0 11 0.7545 small GTPase regulatory/interacting protein activity 30117 18 0 0 2 0.7572 membrane coat 5506 18 0 0 2 0.7572 iron ion binding 8285 18 0 0 2 0.7572 negative regulation of cell proliferation 16023 72 0 0 14 0.7576 cytoplasmic vesicle 4221 19 0 0 4 0.7636 ubiquitin C-terminal hydrolase activity 7185 19 0 0 4 0.7636 transmembrane receptor protein tyrosine phosphatase signaling pathway 6338 20 0 0 4 0.772 chromatin modeling 16582 20 0 0 4 0.772 non-covalent chromatin modification 5834 20 0 0 4 0.772 heterotrimeric G-protein complex 793 20 0 0 4 0.772 condensed chromosome 82 20 0 0 4 0.772 G1/S transition of mitotic cell cycle 7163 21 0 0 4 0.7819 establishment and/or maintenance of cell polarity 5802 21 0 0 4 0.7819 Golgi trans face 3777 23 0 0 3 0.7855 microtubule motor activity 8305 23 0 0 3 0.7855 integrin complex 16790 24 0 0 5 0.7889 thiolester hydrolase activity 6418 25 0 0 5 0.794 amino acid activation 16835 25 0 0 5 0.794 carbon-oxygen lyase activity 5717 25 0 0 5 0.794 chromatin 19953 103 0 0 17 0.7962 sexual reproduction 6576 26 0 0 5 0.8004 biogenic amine metabolism 8757 26 0 0 5 0.8004 S-adenosylmethionine-dependent methyltransferase activity 3713 26 0 0 5 0.8004 transcription co-activator activity 6367 27 0 0 4 0.8058 transcription initiation from Pol II promoter 4895 27 0 0 4 0.8058 cell adhesion receptor activity 9063 27 0 0 4 0.8058 amino acid catabolism 19867 27 0 0 4 0.8058 outer membrane 42056 28 0 0 4 0.8062 chemoattractant activity 1664 29 0 0 4 0.8079 G-protein-coupled receptor binding 6352 29 0 0 4 0.8079 transcription initiation 6519 121 0 0 20 0.811 amino acid and derivative metabolism 16886 30 0 0 6 0.811 "ligase activity, forming phosphoric ester bonds" 16563 30 0 0 6 0.811 transcriptional activator activity 6606 31 0 0 6 0.8153 protein-nucleus import 16538 31 0 0 6 0.8153 "cyclin-dependent protein kinase, regulator activity" 19838 31 0 0 6 0.8153 growth factor binding 3682 31 0 0 6 0.8153 chromatin binding 8238 31 0 0 6 0.8153 exopeptidase activity 9308 130 0 0 22 0.8182 amine metabolism 16705 32 0 0 6 0.8205 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" 9310 32 0 0 6 0.8205 amine catabolism 6633 33 0 0 5 0.8221 fatty acid biosynthesis 6310 36 0 0 7 0.8276 DNA recombination 30036 36 0 0 7 0.8276 actin cytoskeleton organization and biogenesis 15631 36 0 0 7 0.8276 tubulin binding 4693 40 0 0 6 0.8361 cyclin-dependent protein kinase activity 42127 40 0 0 6 0.8361 regulation of cell proliferation 1558 42 0 0 8 0.8406 regulation of cell growth 42579 46 0 0 7 0.8469 microbody 45892 46 0 0 7 0.8469 "negative regulation of transcription, DNA-dependent" 5777 46 0 0 7 0.8469 peroxisome 5941 47 0 0 9 0.8487 unlocalized 5911 53 0 0 10 0.8576 intercellular junction 19207 54 0 0 10 0.8599 kinase regulator activity 16049 55 0 0 9 0.8612 cell growth 16481 56 0 0 9 0.8615 negative regulation of transcription 8134 68 0 0 11 0.8737 transcription factor binding 267 289 0 0 53 0.8756 cell fraction 5509 290 0 0 53 0.876 calcium ion binding 16757 98 0 0 18 0.8949 "transferase activity, transferring glycosyl groups" 3779 120 0 0 22 0.9047 actin binding 8151 1906 0 0 345 0.9155 cell growth and/or maintenance 6082 198 0 0 36 0.9253 organic acid metabolism 19752 198 0 0 36 0.9253 carboxylic acid metabolism 5515 825 0 0 149 0.9614 protein binding 8028 8 0 0 0 1 monocarboxylic acid transporter activity 8027 1 0 0 0 1 sodium/excitatory glutamate symporter activity 8024 1 0 0 0 1 transcription elongation factor complex b 8023 4 0 0 0 1 transcription elongation factor complex 8020 8 0 0 0 1 G-protein coupled photoreceptor activity 8017 34 0 0 6 1 microtubule binding 8016 10 0 0 1 1 regulation of heart rate 8014 7 0 0 1 1 calcium-dependent cell adhesion molecule activity 8013 2 0 0 0 1 beta-catenin binding 8012 1 0 0 0 1 structural constituent of adult cuticle (sensu Insecta) activity 8010 2 0 0 0 1 structural constituent of larval cuticle (sensu Insecta) activity 8009 26 0 0 4 1 chemokine activity 15198 6 0 0 0 1 oligopeptide transporter activity 15197 6 0 0 0 1 peptide transporter activity 15186 2 0 0 0 1 glutamine transporter activity 15179 4 0 0 0 1 L-amino acid transporter activity 15175 3 0 0 0 1 neutral amino acid transporter activity 15174 4 0 0 0 1 basic amino acid transporter activity 15172 1 0 0 0 1 acidic amino acid transporter activity 15159 1 0 0 0 1 polysaccharide transporter activity 15149 8 0 0 1 1 hexose transporter activity 15145 8 0 0 1 1 monosaccharide transporter activity 15144 16 0 0 3 1 carbohydrate transporter activity 15142 6 0 0 0 1 tricarboxylic acid transporter activity 15132 1 0 0 0 1 prostaglandin transporter activity 15125 3 0 0 0 1 bile acid transporter activity 15116 5 0 0 0 1 sulfate transporter activity 15114 1 0 0 0 1 phosphate transporter activity 15111 1 0 0 0 1 iodide transporter activity 15108 11 0 0 0 1 chloride transporter activity 15106 9 0 0 0 1 bicarbonate transporter activity 15105 1 0 0 0 1 arsenite transporter activity 15103 15 0 0 0 1 inorganic anion transporter activity 15101 16 0 0 0 1 organic cation transporter activity 46283 1 0 0 0 1 anthocyanin metabolism 46246 1 0 0 0 1 terpene biosynthesis 46219 1 0 0 0 1 indolalkylamine biosynthesis 46218 1 0 0 0 1 indolalkylamine catabolism 15085 5 0 0 1 1 calcium ion transporter activity 15082 11 0 0 2 1 "di-, tri-valent inorganic cation transporter activity" 15070 4 0 0 0 1 toxin activity 15068 1 0 0 0 1 glycine amidinotransferase activity 15067 1 0 0 0 1 amidinotransferase activity 15057 3 0 0 0 1 thrombin receptor activity 15056 1 0 0 0 1 corticotrophin-releasing factor receptor activity 15055 1 0 0 0 1 secretin receptor activity 15054 1 0 0 0 1 gastrin receptor activity 15038 1 0 0 0 1 glutathione disulfide oxidoreductase activity 15037 1 0 0 0 1 peptide disulfide oxidoreductase activity 15034 8 0 0 0 1 cytochrome P450 activity 15032 1 0 0 0 1 storage protein uptake 15027 3 0 0 0 1 "coreceptor, soluble ligand activity" 15026 6 0 0 0 1 coreceptor activity 15018 2 0 0 0 1 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 15014 1 0 0 0 1 "heparan sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis" 15012 4 0 0 0 1 heparan sulfate proteoglycan biosynthesis 18992 1 0 0 0 1 germ-line sex determination 6998 1 0 0 0 1 nuclear membrane organization and biogenesis 6991 2 0 0 0 1 response to sterol depletion 46160 2 0 0 0 1 heme a metabolism 6986 5 0 0 1 1 response to unfolded protein 18958 8 0 0 1 1 phenol metabolism 46158 1 0 0 0 1 ocellus pigment metabolism 46152 1 0 0 0 1 ommochrome metabolism 6973 1 0 0 0 1 intracellular accumulation of glycerol 6972 1 0 0 0 1 hyperosmotic response 6970 5 0 0 0 1 response to osmotic stress 6967 1 0 0 0 1 antifungal polypeptide induction 6961 1 0 0 0 1 antibacterial humoral response (sensu Invertebrata) 6960 5 0 0 1 1 antimicrobial humoral response (sensu Invertebrata) 6953 13 0 0 0 1 acute-phase response 6944 8 0 0 1 1 membrane fusion 6941 13 0 0 0 1 striated muscle contraction 18916 1 0 0 0 1 nitrobenzene metabolism 46113 1 0 0 0 1 nucleobase catabolism 46112 3 0 0 0 1 nucleobase biosynthesis 6939 3 0 0 0 1 smooth muscle contraction 6938 2 0 0 0 1 sarcomere alignment 6931 1 0 0 0 1 "substrate-bound cell migration, cell attachment to substrate" 6929 2 0 0 0 1 substrate-bound cell migration 6927 2 0 0 0 1 killing transformed cells 6919 9 0 0 1 1 caspase activation 6910 1 0 0 0 1 "phagocytosis, binding" 6909 4 0 0 0 1 phagocytosis 6906 5 0 0 1 1 nonselective vesicle fusion 6904 6 0 0 1 1 nonselective vesicle docking 6903 1 0 0 0 1 nonselective vesicle targeting 46075 2 0 0 0 1 dTTP metabolism 46073 1 0 0 0 1 dTMP metabolism 46072 1 0 0 0 1 dTDP metabolism 46070 1 0 0 0 1 dGTP metabolism 6898 6 0 0 1 1 receptor mediated endocytosis 6893 6 0 0 1 1 Golgi to plasma membrane transport 6890 2 0 0 0 1 retrograde (Golgi to ER) transport 46069 1 0 0 0 1 cGMP catabolism 46068 4 0 0 0 1 cGMP metabolism 6889 1 0 0 0 1 regulation of calcium in ER 6887 22 0 0 4 1 exocytosis 6885 9 0 0 1 1 regulation of pH 6883 2 0 0 0 1 sodium ion homeostasis 46058 7 0 0 0 1 cAMP metabolism 6874 13 0 0 2 1 calcium ion homeostasis 46040 3 0 0 0 1 IMP metabolism 6868 2 0 0 0 1 glutamine transport 46038 1 0 0 0 1 GMP catabolism 46032 1 0 0 0 1 ADP catabolism 46031 1 0 0 0 1 ADP metabolism 46030 2 0 0 0 1 inositol trisphosphate phosphatase activity 6857 6 0 0 0 1 oligopeptide transport 6855 1 0 0 0 1 multidrug transport 46021 1 0 0 0 1 "regulation of transcription from Pol II promoter, mitotic" 46019 2 0 0 0 1 regulation of transcription from Pol II promoter by pheromones 10092 1 0 0 0 1 specification of organ identity 6835 8 0 0 0 1 dicarboxylic acid transport 6833 10 0 0 1 1 water transport 6829 4 0 0 0 1 zinc ion transport 6828 1 0 0 0 1 manganese ion transport 6827 1 0 0 0 1 high affinity iron ion transport 6824 3 0 0 0 1 cobalt ion transport 6823 1 0 0 0 1 heavy metal ion transport 6817 5 0 0 1 1 phosphate transport 6808 1 0 0 0 1 regulation of nitrogen utilization 6805 13 0 0 2 1 xenobiotic metabolism 10035 1 0 0 0 1 response to inorganic substance 10033 1 0 0 0 1 response to organic substance 10025 1 0 0 0 1 wax biosynthesis 10003 2 0 0 0 1 gastrulation (sensu Mammalia) 10001 2 0 0 0 1 glial cell differentiation 6798 1 0 0 0 1 polyphosphate catabolism 6797 1 0 0 0 1 polyphosphate metabolism 6788 2 0 0 0 1 heme oxidation 6784 2 0 0 0 1 heme a biosynthesis 6778 15 0 0 2 1 porphyrin metabolism 6777 4 0 0 0 1 Mo-molybdopterin cofactor biosynthesis 6776 4 0 0 0 1 vitamin A metabolism 6775 5 0 0 0 1 fat-soluble vitamin metabolism 6772 1 0 0 0 1 thiamin metabolism 6760 6 0 0 0 1 folic acid and derivative metabolism 6744 3 0 0 0 1 ubiquinone biosynthesis 6727 1 0 0 0 1 ommochrome biosynthesis 6726 1 0 0 0 1 eye pigment biosynthesis 6725 58 0 0 10 1 aromatic compound metabolism 6721 1 0 0 0 1 terpenoid metabolism 6707 1 0 0 0 1 cholesterol catabolism 6706 1 0 0 0 1 steroid catabolism 6700 10 0 0 0 1 C21-steroid hormone biosynthesis 6699 1 0 0 0 1 bile acid biosynthesis 6696 1 0 0 0 1 ergosterol biosynthesis 6691 10 0 0 1 1 leukotriene metabolism 6690 18 0 0 3 1 eicosanoid metabolism 6670 2 0 0 0 1 sphingosine metabolism 6668 1 0 0 0 1 sphinganine-1-phosphate metabolism 6667 1 0 0 0 1 sphinganine metabolism 6662 6 0 0 0 1 glycerol ether metabolism 6656 1 0 0 0 1 phosphatidylcholine biosynthesis 6653 1 0 0 0 1 lecithin metabolism 6651 1 0 0 0 1 diacylglycerol biosynthesis 6649 1 0 0 0 1 phospholipid transfer to membrane 6646 1 0 0 0 1 phosphatidylethanolamine biosynthesis 6644 28 0 0 5 1 phospholipid metabolism 6642 1 0 0 0 1 triacylglycerol mobilization 6641 4 0 0 0 1 triacylglycerol metabolism 6639 5 0 0 0 1 acylglycerol metabolism 6638 5 0 0 0 1 neutral lipid metabolism 6637 5 0 0 1 1 acyl-CoA metabolism 6635 8 0 0 1 1 fatty acid beta-oxidation 6629 239 0 0 43 1 lipid metabolism 6627 1 0 0 0 1 mitochondrial processing 6625 4 0 0 0 1 protein-peroxisome targeting 6620 12 0 0 2 1 posttranslational membrane targeting 6603 2 0 0 0 1 phosphocreatine metabolism 6601 2 0 0 0 1 creatine biosynthesis 6600 2 0 0 0 1 creatine metabolism 1759 1 0 0 0 1 induction of an organ 1758 2 0 0 0 1 retinal dehydrogenase activity 1756 1 0 0 0 1 somitogenesis 1755 1 0 0 0 1 neural crest cell migration 1754 9 0 0 1 1 eye photoreceptor cell differentiation 1752 1 0 0 0 1 eye photoreceptor fate commitment (sensu Drosophila) 1751 8 0 0 1 1 eye photoreceptor differentiation (sensu Drosophila) 1747 1 0 0 0 1 eye morphogenesis (sensu Mammalia) 1745 9 0 0 1 1 compound eye morphogenesis (sensu Drosophila) 1742 1 0 0 0 1 oenocyte differentiation 1734 1 0 0 0 1 mRNA (N6-adenosine)-methyltransferase activity 1729 1 0 0 0 1 ceramide kinase activity 1727 16 0 0 0 1 lipid kinase activity 1719 1 0 0 0 1 inhibition of caspase activation 1710 1 0 0 0 1 mesoderm cell fate commitment 1709 10 0 0 1 1 cell fate determination 1707 5 0 0 1 1 mesoderm formation 1704 5 0 0 1 1 formation of primary germ layer 1702 2 0 0 0 1 gastrulation (sensu Deuterostoma) 1701 6 0 0 1 1 embryonic development (sensu Mammalia) 1700 15 0 0 2 1 embryonic development (sensu Insecta) 6599 4 0 0 0 1 phosphagen metabolism 6597 1 0 0 0 1 spermine biosynthesis 6592 1 0 0 0 1 ornithine biosynthesis 6591 1 0 0 0 1 ornithine metabolism 6590 2 0 0 0 1 thyroid hormone generation 6587 1 0 0 0 1 serotonin biosynthesis from tryptophan 6586 3 0 0 0 1 indolalkylamine metabolism 6585 2 0 0 0 1 dopamine biosynthesis from tyrosine 6584 8 0 0 1 1 catecholamine metabolism 6583 6 0 0 0 1 melanin biosynthesis from tyrosine 6582 6 0 0 0 1 melanin metabolism 6581 1 0 0 0 1 acetylcholine catabolism 6580 1 0 0 0 1 ethanolamine metabolism 6575 39 0 0 7 1 amino acid derivative metabolism 6572 5 0 0 0 1 tyrosine catabolism 6570 13 0 0 0 1 tyrosine metabolism 6569 1 0 0 0 1 tryptophan catabolism 6568 3 0 0 0 1 tryptophan metabolism 6562 1 0 0 0 1 proline catabolism 6561 2 0 0 0 1 proline biosynthesis 6560 4 0 0 0 1 proline metabolism 6555 7 0 0 0 1 methionine metabolism 6548 3 0 0 0 1 histidine catabolism 6547 5 0 0 0 1 histidine metabolism 6546 1 0 0 0 1 glycine catabolism 6545 1 0 0 0 1 glycine biosynthesis 6544 2 0 0 0 1 glycine metabolism 6542 2 0 0 0 1 glutamine biosynthesis 6541 6 0 0 0 1 glutamine metabolism 6538 1 0 0 0 1 glutamate catabolism 6535 1 0 0 0 1 cysteine biosynthesis from serine 6534 4 0 0 0 1 cysteine metabolism 6533 1 0 0 0 1 aspartate catabolism 6531 1 0 0 0 1 aspartate metabolism 6529 1 0 0 0 1 asparagine biosynthesis 6528 1 0 0 0 1 asparagine metabolism 6518 2 0 0 0 1 peptide metabolism 6516 1 0 0 0 1 glycoprotein catabolism 6515 2 0 0 0 1 misfolded or incompletely synthesized protein catabolism 6513 1 0 0 0 1 protein monoubiquitination 6507 1 0 0 0 1 GPI anchor release 1691 1 0 0 0 1 pseudophosphatase activity 1675 1 0 0 0 1 acrosome formation 1674 1 0 0 0 1 female germ-cell nucleus 1673 2 0 0 0 1 male germ-cell nucleus 1669 2 0 0 0 1 acrosome 1668 1 0 0 0 1 "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity" 1666 5 0 0 0 1 response to hypoxia 1662 3 0 0 0 1 behavioral fear response 1661 1 0 0 0 1 taste aversion 1660 1 0 0 0 1 fever 1659 2 0 0 0 1 thermoregulation 1657 7 0 0 1 1 ureteric bud development 1651 1 0 0 0 1 dense fibrillar component 1649 1 0 0 0 1 osteoblast differentiation 1642 4 0 0 0 1 group III metabotropic glutamate receptor activity 1641 2 0 0 0 1 group II metabotropic glutamate receptor activity 1640 6 0 0 0 1 adenylate cyclase inhibiting metabotropic glutamate receptor activity 1639 2 0 0 0 1 PLC activating metabotropic glutamate receptor activity 1637 18 0 0 0 1 G-protein chemoattractant receptor activity 1636 1 0 0 0 1 corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity 1633 15 0 0 0 1 secretin-like receptor activity 1631 1 0 0 0 1 cysteinyl leukotriene receptor activity 1619 7 0 0 0 1 lysosphingolipid and lysophosphatidic acid receptor activity 1616 1 0 0 0 1 growth hormone secretagogue receptor activity 1615 2 0 0 0 1 thyrotropin releasing hormone and secretagogue-like receptors activity 1614 34 0 0 0 1 purinergic nucleotide receptor activity 1613 1 0 0 0 1 "A3 adenosine receptor activity, G-protein coupled" 1612 1 0 0 0 1 "A2B adenosine receptor activity, G-protein coupled" 1611 1 0 0 0 1 "A2A adenosine receptor activity, G-protein coupled" 1610 1 0 0 0 1 "A1 adenosine receptor activity, G-protein coupled" 1609 4 0 0 0 1 "adenosine receptor activity, G-protein coupled" 1608 34 0 0 0 1 "nucleotide receptor activity, G-protein coupled" 1607 1 0 0 0 1 neuromedin U receptor activity 1602 3 0 0 0 1 pancreatic polypeptide receptor activity 1601 5 0 0 0 1 peptide YY receptor activity 1600 1 0 0 0 1 endothelin-B receptor activity 6499 4 0 0 0 1 N-terminal protein myristoylation 6496 1 0 0 0 1 terminal N-glycosylation 6494 1 0 0 0 1 terminal glycosylation 6491 2 0 0 0 1 N-glycan processing 6481 3 0 0 0 1 C-terminal protein amino acid methylation 6479 3 0 0 0 1 protein amino acid methylation 6477 1 0 0 0 1 protein amino acid sulfation 6476 3 0 0 0 1 protein amino acid deacetylation 6474 1 0 0 0 1 N-terminal protein amino acid acetylation 6461 8 0 0 1 1 protein complex assembly 18410 3 0 0 0 1 peptide/protein carboxyl-terminal blocking 6438 1 0 0 0 1 valyl-tRNA aminoacylation 6435 1 0 0 0 1 threonyl-tRNA aminoacylation 6434 1 0 0 0 1 seryl-tRNA aminoacylation 6432 1 0 0 0 1 phenylalanyl-tRNA aminoacylation 18409 1 0 0 0 1 peptide/protein amino-terminal blocking 6427 2 0 0 0 1 histidyl-tRNA aminoacylation 6426 1 0 0 0 1 glycyl-tRNA aminoacylation 6420 2 0 0 0 1 arginyl-tRNA aminoacylation 6415 1 0 0 0 1 translational termination 6400 1 0 0 0 1 tRNA modification 1595 3 0 0 0 1 angiotensin receptor activity 1591 1 0 0 0 1 dopamine D2 receptor-like receptor activity 1570 1 0 0 0 1 vasculogenesis 1569 2 0 0 0 1 patterning of blood vessels 1565 2 0 0 0 1 phorbol ester receptor activity 1561 1 0 0 0 1 fatty acid alpha-oxidation 1542 1 0 0 0 1 ovulation 1541 3 0 0 0 1 ovarian follicle development 1540 2 0 0 0 1 beta-amyloid binding 1537 1 0 0 0 1 N-acetylgalactosamine-4-O-sulfotransferase activity 1533 3 0 0 0 1 cornified envelope 1530 1 0 0 0 1 lipopolysaccharide binding 1524 1 0 0 0 1 globin 1523 1 0 0 0 1 retinoid metabolism 1520 1 0 0 0 1 outer dense fiber 1518 7 0 0 0 1 voltage-gated sodium channel complex 1516 5 0 0 0 1 prostaglandin biosynthesis 1515 2 0 0 0 1 opioid peptide activity 1510 1 0 0 0 1 RNA methylation 1509 2 0 0 0 1 legumain activity 1504 2 0 0 0 1 neurotransmitter uptake 1502 5 0 0 0 1 cartilage condensation 18377 4 0 0 0 1 protein myristoylation 6399 1 0 0 0 1 tRNA metabolism 6398 1 0 0 0 1 histone mRNA 3'-end processing 6390 1 0 0 0 1 transcription from mitochondrial promoter 6384 1 0 0 0 1 transcription initiation from Pol III promoter 6383 3 0 0 0 1 transcription from Pol III promoter 6381 2 0 0 0 1 mRNA editing 6379 3 0 0 0 1 mRNA cleavage 6378 7 0 0 1 1 mRNA polyadenylation 6369 1 0 0 0 1 transcription termination from Pol II promoter 6365 7 0 0 1 1 35S primary transcript processing 6354 1 0 0 0 1 RNA elongation 6353 1 0 0 0 1 transcription termination 6349 5 0 0 0 1 imprinting 6347 2 0 0 0 1 chromatin silencing at HML and HMR (sensu Saccharomyces) 6340 1 0 0 0 1 OBSOLETE. negative regulation of transcription of homeotic gene (Polycomb group) 18319 4 0 0 0 1 protein amino acid myristoylation 6339 1 0 0 0 1 OBSOLETE. positive regulation of transcription of homeotic gene (trithorax group) 6315 1 0 0 0 1 homing of group II introns 6314 1 0 0 0 1 intron homing 6312 8 0 0 1 1 mitotic recombination 6311 3 0 0 0 1 meiotic gene conversion 18271 1 0 0 0 1 biotin-protein ligase activity 6298 16 0 0 0 1 mismatch repair 6296 1 0 0 0 1 "nucleotide-excision repair, DNA incision, 5' to lesion" 6290 2 0 0 0 1 pyrimidine dimer repair 6287 1 0 0 0 1 "base-excision repair, gap-filling" 6285 1 0 0 0 1 "base-excision repair, AP site formation" 6284 9 0 0 0 1 base-excision repair 6283 2 0 0 0 1 transcription-coupled nucleotide-excision repair 6280 1 0 0 0 1 mutagenesis 6278 1 0 0 0 1 RNA dependent DNA replication 6277 1 0 0 0 1 DNA amplification 6276 1 0 0 0 1 plasmid maintenance 6275 2 0 0 0 1 regulation of DNA replication 6273 1 0 0 0 1 lagging strand elongation 6272 6 0 0 0 1 leading strand elongation 6271 8 0 0 1 1 DNA strand elongation 6270 9 0 0 0 1 DNA replication initiation 6269 1 0 0 0 1 "DNA replication, priming" 6268 6 0 0 1 1 DNA unwinding 6267 7 0 0 0 1 pre-replicative complex formation and maintenance 6259 289 0 0 52 1 DNA metabolism 18212 5 0 0 1 1 peptidyl-tyrosine modification 6235 2 0 0 0 1 dTTP biosynthesis 6233 1 0 0 0 1 dTDP biosynthesis 6231 1 0 0 0 1 dTMP biosynthesis 18206 2 0 0 0 1 peptidyl-methionine modification 18201 2 0 0 0 1 peptidyl-glycine modification 6208 1 0 0 0 1 pyrimidine base catabolism 6207 2 0 0 0 1 'de novo' pyrimidine base biosynthesis 6206 5 0 0 0 1 pyrimidine base metabolism 6203 1 0 0 0 1 dGTP catabolism 6200 1 0 0 0 1 ATP catabolism 6195 5 0 0 0 1 purine nucleotide catabolism 6189 3 0 0 0 1 'de novo' IMP biosynthesis 6188 3 0 0 0 1 IMP biosynthesis 6182 3 0 0 0 1 cGMP biosynthesis 18159 1 0 0 0 1 peptidyl-methionine oxidation 18158 1 0 0 0 1 protein amino acid oxidation 6171 7 0 0 0 1 cAMP biosynthesis 18108 5 0 0 1 1 peptidyl-tyrosine phosphorylation 6113 2 0 0 0 1 fermentation 6104 2 0 0 0 1 succinyl-CoA metabolism 6101 2 0 0 0 1 citrate metabolism 6090 5 0 0 0 1 pyruvate metabolism 18065 1 0 0 0 1 protein-cofactor linkage 6087 5 0 0 0 1 pyruvate dehydrogenase bypass 6086 4 0 0 0 1 acetyl-CoA biosynthesis from pyruvate 6085 5 0 0 0 1 acetyl-CoA biosynthesis 6084 8 0 0 0 1 acetyl-CoA metabolism 6083 6 0 0 0 1 acetate metabolism 6072 2 0 0 0 1 glycerol-3-phosphate metabolism 6071 2 0 0 0 1 glycerol metabolism 6055 1 0 0 0 1 CMP-N-acetylneuraminate biosynthesis 6032 1 0 0 0 1 chitin catabolism 18008 2 0 0 0 1 N-terminal peptidyl-glycine N-myristoylation 6029 8 0 0 0 1 proteoglycan metabolism 6027 1 0 0 0 1 glycosaminoglycan catabolism 6026 1 0 0 0 1 aminoglycan catabolism 6024 2 0 0 0 1 glycosaminoglycan biosynthesis 6023 2 0 0 0 1 aminoglycan biosynthesis 6022 4 0 0 0 1 aminoglycan metabolism 6013 2 0 0 0 1 mannose metabolism 6012 4 0 0 0 1 galactose metabolism 6004 1 0 0 0 1 fucose metabolism 6003 4 0 0 0 1 "fructose 2,6-bisphosphate metabolism" 6000 4 0 0 0 1 fructose metabolism 9991 2 0 0 0 1 response to extracellular stimulus 9986 7 0 0 0 1 cell surface 9956 1 0 0 0 1 radial pattern formation 9954 2 0 0 0 1 proximal/distal pattern formation 9953 11 0 0 0 1 dorsal/ventral pattern formation 9950 6 0 0 0 1 dorsal/ventral axis specification 9948 6 0 0 1 1 anterior/posterior axis specification 9932 1 0 0 0 1 tip growth 9928 5 0 0 0 1 cell surface (sensu Magnoliophyta) 9913 3 0 0 0 1 epidermal cell differentiation 9910 1 0 0 0 1 negative regulation of flower development 9908 6 0 0 1 1 flower development 9895 1 0 0 0 1 negative regulation of catabolism 9894 2 0 0 0 1 regulation of catabolism 9893 1 0 0 0 1 positive regulation of metabolism 9892 2 0 0 0 1 negative regulation of metabolism 9888 23 0 0 4 1 histogenesis 9886 9 0 0 1 1 post-embryonic morphogenesis 9882 2 0 0 0 1 blue light photoreceptor activity 9881 10 0 0 0 1 photoreceptor activity 9880 14 0 0 0 1 embryonic pattern specification 9875 2 0 0 0 1 pollen-pistil interaction 9865 2 0 0 0 1 pollen tube adhesion 9863 1 0 0 0 1 salicylic acid mediated signaling pathway 9862 1 0 0 0 1 salicylic acid mediated signaling pathway (systemic acquired resistance) 9860 2 0 0 0 1 pollen tube growth 9858 2 0 0 0 1 compatible pollen-pistil interaction 9856 2 0 0 0 1 post-pollination 9855 5 0 0 1 1 determination of bilateral symmetry 9854 1 0 0 0 1 oxidative photosynthetic carbon pathway 9853 2 0 0 0 1 photorespiration 9843 2 0 0 0 1 thylakoid (sensu Glaucocystophyceae) 9842 2 0 0 0 1 cyanelle 9813 1 0 0 0 1 flavonoid biosynthesis 9812 1 0 0 0 1 flavonoid metabolism 9809 2 0 0 0 1 lignin biosynthesis 9808 2 0 0 0 1 lignin metabolism 9807 2 0 0 0 1 lignan biosynthesis 9806 2 0 0 0 1 lignan metabolism 16998 2 0 0 0 1 cell wall catabolism 16997 1 0 0 0 1 alpha-sialidase activity 16992 1 0 0 0 1 lipoate synthase activity 16986 2 0 0 0 1 transcription initiation factor activity 16975 1 0 0 0 1 alpha-2 macroglobulin 16973 3 0 0 0 1 poly(A)+ mRNA-nucleus export 16972 1 0 0 0 1 thiol oxidase activity 16971 1 0 0 0 1 flavin-linked sulfhydryl oxidase activity 4999 4 0 0 0 1 vasoactive intestinal polypeptide receptor activity 4997 1 0 0 0 1 thyrotropin-releasing hormone receptor activity 4996 1 0 0 0 1 thyroid-stimulating hormone receptor activity 4995 3 0 0 0 1 tachykinin receptor activity 4994 5 0 0 0 1 somatostatin receptor activity 4993 13 0 0 0 1 serotonin receptor activity 4992 1 0 0 0 1 platelet activating factor receptor activity 4991 1 0 0 0 1 parathyroid hormone receptor activity 4988 1 0 0 0 1 mu-opioid receptor activity 4987 1 0 0 0 1 kappa-opioid receptor activity 4986 1 0 0 0 1 delta-opioid receptor activity 4985 3 0 0 0 1 opioid receptor activity 4983 30 0 0 0 1 neuropeptide Y receptor activity 4982 1 0 0 0 1 N-formyl peptide receptor activity 4981 1 0 0 0 1 muscarinic acetylcholine receptor activity 4980 1 0 0 0 1 melanocyte stimulating hormone receptor activity 4978 1 0 0 0 1 adrenocorticotropin receptor activity 4977 5 0 0 0 1 melanocortin receptor activity 4974 3 0 0 0 1 leukotriene receptor activity 4971 4 0 0 0 1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 4970 15 0 0 0 1 inotropic glutamate receptor activity 16944 4 0 0 0 1 Pol II transcription elongation factor activity 4969 4 0 0 0 1 histamine receptor activity 4968 1 0 0 0 1 gonadotropin-releasing hormone receptor activity 4967 3 0 0 0 1 glucagon receptor activity 4966 3 0 0 0 1 galanin receptor activity 4964 1 0 0 0 1 lutropin-choriogonadotropic hormone receptor activity 4963 1 0 0 0 1 follicle stimulating hormone receptor activity 4962 2 0 0 0 1 endothelin receptor activity 4960 1 0 0 0 1 thromboxane receptor activity 16937 1 0 0 0 1 short branched-chain acyl-CoA dehydrogenase activity 16934 1 0 0 0 1 glycine-gated chloride channel activity 16933 1 0 0 0 1 glycine-gated ion channel activity 4959 1 0 0 0 1 prostaglandin I receptor activity 4958 1 0 0 0 1 prostaglandin F receptor activity 4957 4 0 0 0 1 prostaglandin E receptor activity 4956 1 0 0 0 1 prostaglandin D receptor activity 4955 7 0 0 0 1 prostaglandin receptor activity 4954 8 0 0 0 1 prostanoid receptor activity 4953 8 0 0 0 1 eicosanoid receptor activity 4952 3 0 0 0 1 dopamine receptor activity 4951 2 0 0 0 1 cholecystokinin receptor activity 4950 18 0 0 0 1 chemokine receptor activity 16925 1 0 0 0 1 protein sumoylation 4949 2 0 0 0 1 cannabinoid receptor activity 4948 1 0 0 0 1 calcitonin receptor activity 4947 1 0 0 0 1 bradykinin receptor activity 4946 4 0 0 0 1 bombesin receptor activity 4945 3 0 0 0 1 angiotensin type II receptor activity 4944 1 0 0 0 1 C5a anaphylatoxin receptor activity 4943 1 0 0 0 1 C3a anaphylatoxin receptor activity 4942 4 0 0 0 1 anaphylatoxin receptor activity 4941 1 0 0 0 1 beta2-adrenergic receptor activity 4940 1 0 0 0 1 beta1-adrenergic receptor activity 16917 29 0 0 0 1 GABA receptor activity 16916 1 0 0 0 1 inhibin 4939 3 0 0 0 1 beta-adrenergic receptor activity 4938 3 0 0 0 1 alpha2-adrenergic receptor activity 4937 3 0 0 0 1 alpha1-adrenergic receptor activity 4936 6 0 0 0 1 alpha-adrenergic receptor activity 4935 17 0 0 0 1 adrenoceptor activity 4931 5 0 0 0 1 ATP-gated cation channel activity 16909 1 0 0 0 1 SAP kinase activity 16902 1 0 0 0 1 "oxidoreductase activity, acting on the CH-OH group of donors, other acceptors" 4928 10 0 0 0 1 frizzled receptor activity 4926 13 0 0 0 1 non-G-protein coupled 7TM receptor activity 4924 1 0 0 0 1 oncostatin-M receptor activity 4920 1 0 0 0 1 interleukin-10 receptor activity 4918 1 0 0 0 1 interleukin-8 receptor activity 4910 1 0 0 0 1 "interleukin-1, Type II, blocking receptor activity" 4909 10 0 0 0 1 "interleukin-1, Type I, activating receptor activity" 4908 11 0 0 0 1 interleukin-1 receptor activity 4905 1 0 0 0 1 interferon-alpha/beta receptor activity 4904 1 0 0 0 1 interferon receptor activity 9799 5 0 0 1 1 determination of symmetry 9796 1 0 0 0 1 cellularization (sensu Animalia) 9794 1 0 0 0 1 "regulation of mitotic cell cycle, embryonic" 9793 1 0 0 0 1 embryonic development (sensu Magnoliophyta) 9785 1 0 0 0 1 blue light signaling pathway 9751 1 0 0 0 1 response to salicylic acid stimulus 9744 1 0 0 0 1 response to sucrose stimulus 9743 1 0 0 0 1 response to carbohydrate stimulus 9740 1 0 0 0 1 gibberellic acid mediated signaling 9739 1 0 0 0 1 response to gibberellic acid stimulus 9718 1 0 0 0 1 anthocyanin biosynthesis 16899 3 0 0 0 1 "oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor" 16896 7 0 0 0 1 "exoribonuclease activity, producing 5'-phosphomonoesters" 16892 5 0 0 0 1 "endoribonuclease activity, producing other than 5'-phosphomonoesters" 16891 7 0 0 1 1 "endoribonuclease activity, producing 5'-phosphomonoesters" 16889 1 0 0 0 1 "endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters" 16888 2 0 0 0 1 "endodeoxyribonuclease activity, producing 5'-phosphomonoesters" 16884 6 0 0 0 1 "carbon-nitrogen ligase activity, with glutamine as amido-N-donor" 16882 1 0 0 0 1 cyclo-ligase activity 16877 6 0 0 1 1 "ligase activity, forming carbon-sulfur bonds" 16870 1 0 0 0 1 "intramolecular transferase activity, transferring other groups" 4891 1 0 0 0 1 glycine-inhibited chloride channel activity 4890 29 0 0 0 1 GABA-A receptor activity 16863 6 0 0 0 1 "intramolecular isomerase activity, transposing C=C bonds" 4889 13 0 0 0 1 nicotinic acetylcholine-activated cation-selective channel activity 4887 3 0 0 0 1 thyroid hormone receptor activity 4882 1 0 0 0 1 androgen receptor activity 16858 1 0 0 0 1 "racemase and epimerase activity, acting on other compounds" 16857 2 0 0 0 1 "racemase and epimerase activity, acting on carbohydrates and derivatives" 16856 1 0 0 0 1 "racemase and epimerase activity, acting on hydroxy acids and derivatives" 16855 1 0 0 0 1 "racemase and epimerase activity, acting on amino acids and derivatives" 16854 5 0 0 0 1 racemase and epimerase activity 16850 1 0 0 0 1 other lyase activity 4878 1 0 0 0 1 complement component C5 receptor activity 4875 1 0 0 0 1 complement receptor activity 16849 13 0 0 0 1 phosphorus-oxygen lyase activity 16846 5 0 0 1 1 carbon-sulfur lyase activity 16841 4 0 0 0 1 ammonia-lyase activity 4868 1 0 0 0 1 serpin 4861 8 0 0 0 1 cyclin-dependent protein kinase inhibitor activity 16836 21 0 0 3 1 hydro-lyase activity 16834 1 0 0 0 1 other carbon-carbon lyase activity 16833 6 0 0 1 1 oxo-acid-lyase activity 16830 28 0 0 5 1 carbon-carbon lyase activity 4855 1 0 0 0 1 xanthine oxidase activity 4854 1 0 0 0 1 xanthine dehydrogenase activity 4853 1 0 0 0 1 uroporphyrinogen decarboxylase activity 4852 1 0 0 0 1 uroporphyrinogen-III synthase activity 16824 3 0 0 0 1 "hydrolase activity, acting on acid halide bonds" 16823 2 0 0 0 1 "hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances" 16822 2 0 0 0 1 "hydrolase activity, acting on acid carbon-carbon bonds" 16821 5 0 0 0 1 "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement" 4849 1 0 0 0 1 uridine kinase activity 4844 1 0 0 0 1 uracil DNA N-glycosylase activity 16814 14 0 0 2 1 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" 16813 9 0 0 1 1 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines" 16812 1 0 0 0 1 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides" 16810 38 0 0 7 1 "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" 4838 1 0 0 0 1 tyrosine aminotransferase activity 4833 1 0 0 0 1 "tryptophan 2,3 dioxygenase activity" 4832 1 0 0 0 1 valine-tRNA ligase activity 16808 2 0 0 0 1 proprotein convertase activity 16805 6 0 0 0 1 dipeptidase activity 4829 1 0 0 0 1 threonine-tRNA ligase activity 4828 1 0 0 0 1 serine-tRNA ligase activity 4826 1 0 0 0 1 phenylalanine-tRNA ligase activity 4821 2 0 0 0 1 histidine-tRNA ligase activity 4820 1 0 0 0 1 glycine-tRNA ligase activity 4814 2 0 0 0 1 arginine-tRNA ligase activity 4806 5 0 0 0 1 triacylglycerol lipase activity 4800 3 0 0 0 1 thyroxine deiodinase activity 9699 3 0 0 0 1 phenylpropanoid biosynthesis 9698 3 0 0 0 1 phenylpropanoid metabolism 9651 1 0 0 0 1 salinity response 9649 2 0 0 0 1 entrainment of circadian clock 9648 2 0 0 0 1 response to photoperiod 9639 1 0 0 0 1 response to red/far-red light 9638 2 0 0 0 1 phototropism 9637 2 0 0 0 1 response to blue light 9630 1 0 0 0 1 gravitropism 9629 1 0 0 0 1 response to gravity 9627 1 0 0 0 1 systemic acquired resistance 9624 1 0 0 0 1 response to nematodes 9621 2 0 0 0 1 response to pathogenic fungi 9620 5 0 0 1 1 response to fungi 9612 2 0 0 0 1 response to mechanical stimulus 9606 3 0 0 0 1 tropism 16799 9 0 0 0 1 "hydrolase activity, hydrolyzing N-glycosyl compounds" 16784 2 0 0 0 1 3-mercaptopyruvate sulfurtransferase activity 16783 3 0 0 0 1 sulfurtransferase activity 16781 1 0 0 0 1 "phosphotransferase activity, paired acceptors" 16780 6 0 0 1 1 "phosphotransferase activity, for other substituted phosphate groups" 4799 1 0 0 0 1 thymidylate synthase activity 4798 1 0 0 0 1 thymidylate kinase activity 4797 2 0 0 0 1 thymidine kinase activity 4796 1 0 0 0 1 thromboxane-A synthase activity 4794 1 0 0 0 1 threonine dehydratase activity 4792 2 0 0 0 1 thiosulfate sulfurtransferase activity 16769 21 0 0 3 1 "transferase activity, transferring nitrogenous groups" 16768 1 0 0 0 1 spermine synthase activity 16763 10 0 0 1 1 "transferase activity, transferring pentosyl groups" 4788 1 0 0 0 1 thiamin pyrophosphokinase activity 4782 1 0 0 0 1 sulfinoalanine decarboxylase activity 4777 1 0 0 0 1 succinate-semialdehyde dehydrogenase activity 4774 1 0 0 0 1 succinate-CoA ligase activity 4773 1 0 0 0 1 steryl-sulfatase activity 4772 1 0 0 0 1 sterol O-acyltransferase activity 4770 1 0 0 0 1 sterol carrier protein X-related thiolase activity 16743 1 0 0 0 1 carboxyl- and carbamoyltransferase activity 4769 2 0 0 0 1 steroid delta-isomerase activity 4767 2 0 0 0 1 sphingomyelin phosphodiesterase activity 4766 1 0 0 0 1 spermidine synthase activity 16731 1 0 0 0 1 "oxidoreductase activity, acting on reduced ferredoxin as donor, NAD or NADP as acceptor" 16730 1 0 0 0 1 "oxidoreductase activity, acting on iron-sulfur proteins as donors" 4759 7 0 0 0 1 serine esterase activity 4758 2 0 0 0 1 serine C-palmitoyltransferase activity 4757 1 0 0 0 1 sepiapterin reductase activity 4756 1 0 0 0 1 "selenide, water dikinase activity" 4751 1 0 0 0 1 ribose-5-phosphate isomerase activity 4750 1 0 0 0 1 ribulose-phosphate 3-epimerase activity 4745 1 0 0 0 1 retinol dehydrogenase activity 4742 1 0 0 0 1 dihydrolipoamide S-acetyltransferase activity 16716 1 0 0 0 1 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen" 16715 2 0 0 0 1 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen" 16714 2 0 0 0 1 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen" 4736 1 0 0 0 1 pyruvate carboxylase activity 4735 1 0 0 0 1 pyrroline 5-carboxylate reductase activity 4731 1 0 0 0 1 purine-nucleoside phosphorylase activity 4730 2 0 0 0 1 pseudouridylate synthase activity 16709 10 0 0 1 1 "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen" 4726 6 0 0 0 1 non-membrane spanning protein tyrosine phosphatase activity 4724 1 0 0 0 1 magnesium-dependent protein serine/threonine phosphatase activity 4720 2 0 0 0 1 protein-lysine 6-oxidase activity 4719 1 0 0 0 1 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 4718 2 0 0 0 1 Janus kinase activity 4716 4 0 0 0 1 receptor signaling protein tyrosine kinase activity 4709 7 0 0 0 1 MAP kinase kinase kinase activity 4705 1 0 0 0 1 JUN kinase activity 4703 6 0 0 1 1 G-protein coupled receptor kinase activity 9592 12 0 0 2 1 perception of sound 9591 2 0 0 0 1 perception of mechanical stimulus 9586 1 0 0 0 1 rhodopsin mediated phototransduction 9579 3 0 0 0 1 thylakoid 9570 1 0 0 0 1 chloroplast stroma 9535 1 0 0 0 1 thylakoid membrane (sensu Viridiplantae) 9534 1 0 0 0 1 thylakoid (sensu Viridiplantae) 16671 2 0 0 0 1 "oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor" 16670 1 0 0 0 1 "oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor" 4699 1 0 0 0 1 calcium independent protein kinase C activity 4698 1 0 0 0 1 calcium dependent protein kinase C activity 4697 2 0 0 0 1 protein kinase C activity 4696 1 0 0 0 1 glycogen synthase kinase 3 activity 4692 2 0 0 0 1 cGMP-dependent protein kinase activity 16667 5 0 0 1 1 "oxidoreductase activity, acting on sulfur group of donors" 16666 1 0 0 0 1 nitrite reductase activity 16665 1 0 0 0 1 "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors" 16661 1 0 0 0 1 "oxidoreductase activity, acting on other nitrogenous compounds as donors" 4685 6 0 0 0 1 calcium/calmodulin-dependent protein kinase activity 4684 2 0 0 0 1 calmodulin-dependent protein kinase I activity 4683 10 0 0 1 1 calmodulin regulated protein kinase activity 16657 2 0 0 0 1 "oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor" 16650 1 0 0 0 1 "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors" 4679 7 0 0 0 1 SNF1A/AMP-activated protein kinase activity 4676 1 0 0 0 1 3-phosphoinositide-dependent protein kinase activity 4675 12 0 0 2 1 transmembrane receptor protein serine/threonine kinase activity 4673 4 0 0 0 1 protein histidine kinase activity 4671 1 0 0 0 1 protein-S-isoprenylcysteine O-methyltransferase activity 16649 1 0 0 0 1 "oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor" 16647 1 0 0 0 1 "oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor" 16646 5 0 0 0 1 "oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor" 16645 8 0 0 0 1 "oxidoreductase activity, acting on the CH-NH group of donors" 16642 1 0 0 0 1 "oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor" 16641 6 0 0 0 1 "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" 4668 4 0 0 0 1 protein-arginine deiminase activity 4666 2 0 0 0 1 prostaglandin-endoperoxide synthase activity 16639 1 0 0 0 1 "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor" 16638 8 0 0 0 1 "oxidoreductase activity, acting on the CH-NH2 group of donors" 16637 12 0 0 2 1 "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors" 16634 6 0 0 1 1 "oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor" 4658 2 0 0 0 1 propionyl-CoA carboxylase activity 4657 1 0 0 0 1 proline dehydrogenase activity 4655 1 0 0 0 1 porphobilinogen synthase activity 16624 6 0 0 1 1 "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor" 16623 1 0 0 0 1 "oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor" 16621 2 0 0 0 1 cinnamoyl-CoA reductase activity 4649 1 0 0 0 1 poly(ADP-ribose) glycohydrolase activity 4645 5 0 0 0 1 phosphorylase activity 4644 1 0 0 0 1 phosphoribosylglycinamide formyltransferase activity 4641 1 0 0 0 1 phosphoribosylformylglycinamidine cyclo-ligase activity 16619 1 0 0 0 1 malate dehydrogenase (oxaloacetate decarboxylating) activity 4639 1 0 0 0 1 phosphoribosylaminoimidazole-succinocarboxamide synthase activity 4638 1 0 0 0 1 phosphoribosylaminoimidazole carboxylase activity 4637 2 0 0 0 1 phosphoribosylamine-glycine ligase activity 4630 4 0 0 0 1 phospholipase D activity 16605 3 0 0 0 1 PML body 16602 1 0 0 0 1 CCAAT-binding factor complex 4629 8 0 0 1 1 phospholipase C activity 4628 1 0 0 0 1 calcium-independent cytosolic phospholipase A2 activity 4626 1 0 0 0 1 cytosolic phospholipase A2 activity 4624 1 0 0 0 1 secreted phospholipase A2 activity 4621 1 0 0 0 1 glycoprotein phospholipase D activity 4615 2 0 0 0 1 phosphomannomutase activity 4613 1 0 0 0 1 phosphoenolpyruvate carboxykinase (GTP) activity 4612 1 0 0 0 1 phosphoenolpyruvate carboxykinase (ATP) activity 4611 2 0 0 0 1 phosphoenolpyruvate carboxykinase activity 4608 1 0 0 0 1 phosphatidylethanolamine N-methyltransferase activity 4607 1 0 0 0 1 phosphatidylcholine-sterol O-acyltransferase activity 4604 1 0 0 0 1 phosphoadenylyl-sulfate reductase (thioredoxin) activity 4603 1 0 0 0 1 phenylethanolamine N-methyltransferase activity 9492 2 0 0 0 1 2Fe-2S electron transfer carrier 9457 1 0 0 0 1 flavodoxin 9453 1 0 0 0 1 energy taxis 9434 2 0 0 0 1 flagellum (sensu Eukarya) 9432 1 0 0 0 1 SOS response 9417 1 0 0 0 1 fimbrin 9411 1 0 0 0 1 response to UV 9410 13 0 0 2 1 response to xenobiotic stimulus 9409 2 0 0 0 1 response to cold 9405 8 0 0 0 1 pathogenesis 16597 2 0 0 0 1 amino acid binding 16581 1 0 0 0 1 NuRD complex 16579 6 0 0 1 1 protein deubiquitination 16575 1 0 0 0 1 histone deacetylation 4598 1 0 0 0 1 peptidylamidoglycolate lyase activity 4597 1 0 0 0 1 peptide-aspartate beta-dioxygenase activity 4591 1 0 0 0 1 oxoglutarate dehydrogenase (lipoamide) activity 4590 1 0 0 0 1 orotidine-5'-phosphate decarboxylase activity 16566 2 0 0 0 1 specific transcriptional repressor activity 16565 1 0 0 0 1 general transcriptional repressor activity 4588 1 0 0 0 1 orotate phosphoribosyltransferase activity 4587 1 0 0 0 1 ornithine-oxo-acid aminotransferase activity 4586 1 0 0 0 1 ornithine decarboxylase activity 4585 1 0 0 0 1 ornithine carbamoyltransferase activity 16556 3 0 0 0 1 mRNA modification 16554 1 0 0 0 1 cytidine to uridine editing 4572 1 0 0 0 1 "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity" 16541 1 0 0 0 1 intein 4568 1 0 0 0 1 chitinase activity 4565 2 0 0 0 1 beta-galactosidase activity 16539 2 0 0 0 1 protein splicing 16534 1 0 0 0 1 cyclin-dependent protein kinase 5 activator activity 16533 1 0 0 0 1 cyclin-dependent protein kinase 5 activator complex 16532 1 0 0 0 1 superoxide dismutase copper chaperone activity 16531 1 0 0 0 1 copper chaperone activity 16530 1 0 0 0 1 metallochaperone activity 4558 3 0 0 0 1 alpha-glucosidase activity 4557 2 0 0 0 1 alpha-galactosidase activity 4556 3 0 0 0 1 alpha-amylase activity 4555 1 0 0 0 1 "alpha,alpha-trehalase activity" 4553 36 0 0 6 1 "hydrolase activity, hydrolyzing O-glycosyl compounds" 4551 2 0 0 0 1 nucleotide pyrophosphatase activity 16529 8 0 0 1 1 sarcoplasmic reticulum 16528 8 0 0 1 1 sarcoplasm 16527 3 0 0 0 1 brain-specific angiogenesis inhibitor activity 16525 4 0 0 0 1 negative regulation of angiogenesis 16520 1 0 0 0 1 growth hormone-releasing hormone receptor activity 16514 5 0 0 1 1 SWI/SNF complex 16511 2 0 0 0 1 endothelin-converting enzyme activity 4536 9 0 0 0 1 deoxyribonuclease activity 4532 7 0 0 0 1 exoribonuclease activity 4530 2 0 0 0 1 deoxyribonuclease I activity 16509 1 0 0 0 1 long-chain 3-hydroxyacyl-CoA dehydrogenase activity 16506 11 0 0 2 1 apoptosis activator activity 16505 2 0 0 0 1 apoptotic protease activator activity 16504 2 0 0 0 1 protease activator activity 16502 34 0 0 0 1 nucleotide receptor activity 16500 5 0 0 0 1 protein-hormone receptor activity 4529 1 0 0 0 1 exodeoxyribonuclease activity 4528 2 0 0 0 1 phosphodiesterase I activity 4527 22 0 0 0 1 exonuclease activity 4525 1 0 0 0 1 ribonuclease III activity 4524 1 0 0 0 1 ribonuclease H1 activity 4523 1 0 0 0 1 ribonuclease H activity 4522 5 0 0 0 1 pancreatic ribonuclease activity 4520 8 0 0 0 1 endodeoxyribonuclease activity 4517 2 0 0 0 1 nitric oxide synthase activity 4511 1 0 0 0 1 tyrosine 3-monooxygenase activity 4508 1 0 0 0 1 steroid 17-alpha-monooxygenase activity 4505 1 0 0 0 1 phenylalanine 4-monooxygenase activity 4504 1 0 0 0 1 peptidyl-glycine monooxygenase activity 4503 1 0 0 0 1 monophenol monooxygenase activity 4500 1 0 0 0 1 dopamine-beta-monooxygenase activity 9396 3 0 0 0 1 folic acid and derivative biosynthesis 9395 2 0 0 0 1 phospholipid catabolism 9384 1 0 0 0 1 N-acylmannosamine kinase activity 9373 2 0 0 0 1 regulation of transcription by pheromones 9371 2 0 0 0 1 positive regulation of transcription by pheromones 9348 1 0 0 0 1 ornithine carbamoyltransferase complex 9343 2 0 0 0 1 biotin carboxylase complex 9341 1 0 0 0 1 beta-galactosidase complex 9331 2 0 0 0 1 glycerol-3-phosphate dehydrogenase complex 9320 1 0 0 0 1 phosphoribosylaminoimidazole carboxylase complex 9317 2 0 0 0 1 acetyl-CoA carboxylase complex 9312 4 0 0 0 1 oligosaccharide biosynthesis 9311 4 0 0 0 1 oligosaccharide metabolism 9306 7 0 0 0 1 protein secretion 42770 15 0 0 2 1 "DNA damage response, signal transduction" 16499 1 0 0 0 1 orexin receptor activity 16494 5 0 0 0 1 C-X-C chemokine receptor activity 16493 12 0 0 0 1 C-C chemokine receptor activity 16486 4 0 0 0 1 peptide hormone processing 16485 10 0 0 0 1 protein processing 16482 1 0 0 0 1 cytoplasmic transport 16478 1 0 0 0 1 negative regulation of translation 4499 5 0 0 0 1 dimethylaniline monooxygenase (N-oxide forming) activity 4494 1 0 0 0 1 methylmalonyl-CoA mutase activity 4492 1 0 0 0 1 methylmalonyl-CoA decarboxylase activity 4491 1 0 0 0 1 methylmalonate-semialdehyde dehydrogenase (acylating) activity 42723 1 0 0 0 1 thiamin and derivative metabolism 16462 4 0 0 0 1 pyrophosphatase activity 16461 1 0 0 0 1 unconventional myosin 16460 6 0 0 0 1 myosin II 4489 1 0 0 0 1 methylenetetrahydrofolate reductase (NADPH) activity 4488 2 0 0 0 1 methylenetetrahydrofolate dehydrogenase (NADP+) activity 4486 2 0 0 0 1 methylenetetrahydrofolate dehydrogenase activity 4484 1 0 0 0 1 mRNA guanylyltransferase activity 16459 22 0 0 0 1 myosin 16458 16 0 0 3 1 gene silencing 16455 6 0 0 1 1 RNA polymerase II transcription mediator activity 16454 2 0 0 0 1 C-palmitoyltransferase activity 16452 2 0 0 0 1 theta DNA polymerase activity 16451 3 0 0 0 1 nu DNA polymerase activity 16450 2 0 0 0 1 kappa DNA polymerase activity 4478 1 0 0 0 1 methionine adenosyltransferase activity 4477 2 0 0 0 1 methenyltetrahydrofolate cyclohydrolase activity 4476 1 0 0 0 1 mannose-6-phosphate isomerase activity 42708 2 0 0 0 1 elastase activity 4471 1 0 0 0 1 malate dehydrogenase (decarboxylating) activity 42706 1 0 0 0 1 eye photoreceptor cell fate commitment 16449 2 0 0 0 1 lambda DNA polymerase activity 16448 2 0 0 0 1 mu DNA polymerase activity 16444 1 0 0 0 1 somatic cell DNA recombination 4466 1 0 0 0 1 long-chain acyl-CoA dehydrogenase activity 4465 1 0 0 0 1 lipoprotein lipase activity 4464 1 0 0 0 1 leukotriene-C4 synthase activity 4461 2 0 0 0 1 lactose synthase activity 4454 1 0 0 0 1 ketohexokinase activity 4452 1 0 0 0 1 isopentenyl-diphosphate delta-isomerase activity 4451 1 0 0 0 1 isocitrate lyase activity 4447 1 0 0 0 1 iodide peroxidase activity 4445 2 0 0 0 1 "inositol-1,4,5-trisphosphate 5-phosphatase activity" 16418 1 0 0 0 1 S-acetyltransferase activity 16417 1 0 0 0 1 S-acyltransferase activity 16416 2 0 0 0 1 O-palmitoyltransferase activity 16415 1 0 0 0 1 octanoyltransferase activity 16414 1 0 0 0 1 O-octanoyltransferase activity 16413 4 0 0 0 1 O-acetyltransferase activity 4438 1 0 0 0 1 phosphatidylinositol-3-phosphatase activity 4437 16 0 0 3 1 inositol/phosphatidylinositol phosphatase activity 4435 7 0 0 0 1 "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity" 4434 7 0 0 0 1 inositol/phosphatidylinositol phosphodiesterase activity 4430 1 0 0 0 1 1-phosphatidylinositol 4-kinase activity 16409 4 0 0 0 1 palmitoyltransferase activity 16406 4 0 0 0 1 carnitine O-acyltransferase activity 16402 1 0 0 0 1 pristanoyl-CoA oxidase activity 4428 19 0 0 0 1 inositol/phosphatidylinositol kinase activity 4427 2 0 0 0 1 inorganic diphosphatase activity 4426 1 0 0 0 1 "indoleamine-pyrrole 2,3-dioxygenase activity" 4423 1 0 0 0 1 iduronate-2-sulfatase activity 4421 3 0 0 0 1 hydroxymethylglutaryl-CoA synthase activity 4420 1 0 0 0 1 hydroxymethylglutaryl-CoA reductase (NADPH) activity 4418 1 0 0 0 1 hydroxymethylbilane synthase activity 4416 1 0 0 0 1 hydroxyacylglutathione hydrolase activity 4415 3 0 0 0 1 hyaluronoglucosaminidase activity 4411 1 0 0 0 1 "homogentisate 1,2-dioxygenase activity" 4408 1 0 0 0 1 holocytochrome c synthase activity 9289 1 0 0 0 1 fimbria 9277 1 0 0 0 1 cell wall (sensu Fungi) 9268 2 0 0 0 1 response to pH 9267 1 0 0 0 1 cellular response to starvation 9264 2 0 0 0 1 deoxyribonucleotide catabolism 9263 3 0 0 0 1 deoxyribonucleotide biosynthesis 9262 6 0 0 0 1 deoxyribonucleotide metabolism 9261 4 0 0 0 1 ribonucleotide catabolism 9250 7 0 0 0 1 glucan biosynthesis 9241 1 0 0 0 1 polyisoprenoid biosynthesis 9221 3 0 0 0 1 pyrimidine deoxyribonucleotide biosynthesis 9219 3 0 0 0 1 pyrimidine deoxyribonucleotide metabolism 9217 1 0 0 0 1 purine deoxyribonucleoside triphosphate catabolism 9215 1 0 0 0 1 purine deoxyribonucleoside triphosphate metabolism 9214 1 0 0 0 1 cyclic nucleotide catabolism 9212 2 0 0 0 1 pyrimidine deoxyribonucleoside triphosphate biosynthesis 9211 2 0 0 0 1 pyrimidine deoxyribonucleoside triphosphate metabolism 9207 1 0 0 0 1 purine ribonucleoside triphosphate catabolism 9204 1 0 0 0 1 deoxyribonucleoside triphosphate catabolism 9203 1 0 0 0 1 ribonucleoside triphosphate catabolism 9202 2 0 0 0 1 deoxyribonucleoside triphosphate biosynthesis 9200 3 0 0 0 1 deoxyribonucleoside triphosphate metabolism 42698 4 0 0 0 1 menstrual cycle 42676 1 0 0 0 1 cone cell fate commitment 42675 1 0 0 0 1 cone cell differentiation 42674 1 0 0 0 1 cone cell differentiation (sensu Drosophila) 42651 1 0 0 0 1 thylakoid membrane 30677 5 0 0 1 1 ribonuclease P complex 30672 2 0 0 0 1 synaptic vesicle membrane 30665 1 0 0 0 1 clathrin coated vesicle membrane 30662 1 0 0 0 1 coated vesicle membrane 30660 1 0 0 0 1 Golgi vesicle membrane 30659 2 0 0 0 1 cytoplasmic vesicle membrane 30658 1 0 0 0 1 transport vesicle membrane 4398 1 0 0 0 1 histidine decarboxylase activity 4397 1 0 0 0 1 histidine ammonia-lyase activity 4396 5 0 0 0 1 hexokinase activity 4395 1 0 0 0 1 hexaprenyldihydroxybenzoate methyltransferase activity 4394 2 0 0 0 1 heparin-sulfate 2-sulfotransferase activity 4393 2 0 0 0 1 heparin N-deacetylase/N-sulfotransferase activity 4392 3 0 0 0 1 heme oxygenase (decyclizing) activity 16360 1 0 0 0 1 sensory organ precursor cell fate determination 4385 7 0 0 1 1 guanylate kinase activity 30641 9 0 0 1 1 hydrogen ion homeostasis 4383 11 0 0 0 1 guanylate cyclase activity 4381 1 0 0 0 1 glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity 4380 1 0 0 0 1 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity 4379 2 0 0 0 1 glycyl-peptide N-tetradecanoyltransferase activity 4375 1 0 0 0 1 glycine dehydrogenase (decarboxylating) activity 4373 1 0 0 0 1 glycogen (starch) synthase activity 42607 2 0 0 0 1 exogenous peptide antigen binding 42605 2 0 0 0 1 peptide antigen binding 16343 1 0 0 0 1 cytoskeletal anchor protein activity 4368 1 0 0 0 1 glycerol-3-phosphate dehydrogenase activity 4367 2 0 0 0 1 glycerol-3-phosphate dehydrogenase (NAD+) activity 4362 1 0 0 0 1 glutathione reductase (NADPH) activity 4361 1 0 0 0 1 glutaryl-CoA dehydrogenase activity 4360 2 0 0 0 1 glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity 16339 2 0 0 0 1 calcium-dependent cell-cell adhesion 16336 2 0 0 0 1 establishment and/or maintenance of polarity of larval imaginal disc epithelium 16334 2 0 0 0 1 establishment and/or maintenance of polarity of follicular epithelium 16333 2 0 0 0 1 morphogenesis of follicular epithelium 16332 2 0 0 0 1 establishment and/or maintenance of polarity of embryonic epithelium 16331 3 0 0 0 1 morphogenesis of embryonic epithelium 16330 1 0 0 0 1 second mitotic wave (sensu Drosophila) 30618 1 0 0 0 1 "TGFbeta receptor, pathway-specific cytoplasmic mediator activity" 4359 1 0 0 0 1 glutaminase activity 30614 1 0 0 0 1 "oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor" 30613 1 0 0 0 1 "oxidoreductase activity, acting on phosphorus or arsenic in donors" 4353 1 0 0 0 1 glutamate dehydrogenase (NAD(P)+) activity 4351 2 0 0 0 1 glutamate decarboxylase activity 4350 1 0 0 0 1 glutamate-5-semialdehyde dehydrogenase activity 16328 1 0 0 0 1 lateral plasma membrane 16326 6 0 0 1 1 kinesin motor activity 16325 1 0 0 0 1 oocyte microtubule cytoskeleton organization 16324 7 0 0 1 1 apical plasma membrane 16323 4 0 0 0 1 basolateral plasma membrane 16322 2 0 0 0 1 neuronal remodeling 16321 3 0 0 0 1 female meiosis chromosome segregation 4349 1 0 0 0 1 glutamate 5-kinase activity 4348 1 0 0 0 1 glucosylceramidase activity 4346 1 0 0 0 1 glucose-6-phosphatase activity 4342 1 0 0 0 1 glucosamine-6-phosphate deaminase activity 4340 1 0 0 0 1 glucokinase activity 16318 1 0 0 0 1 ommatidial rotation 16316 1 0 0 0 1 "inositol-3,4-bisphosphate 4-phosphatase activity" 16314 1 0 0 0 1 "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity" 4335 1 0 0 0 1 galactokinase activity 4334 1 0 0 0 1 fumarylacetoacetase activity 4331 3 0 0 0 1 "fructose-2,6-bisphosphate 2-phosphatase activity" 16308 5 0 0 0 1 1-phosphatidylinositol-4-phosphate 5-kinase activity 16307 6 0 0 0 1 phosphatidylinositol phosphate kinase activity 16303 7 0 0 0 1 phosphatidylinositol 3-kinase activity 4329 1 0 0 0 1 formate-tetrahydrofolate ligase activity 4326 1 0 0 0 1 folylpolyglutamate synthase activity 4325 1 0 0 0 1 ferrochelatase activity 4324 1 0 0 0 1 ferredoxin-NADP reductase activity 4312 1 0 0 0 1 fatty-acid synthase activity 4308 1 0 0 0 1 exo-alpha-sialidase activity 4307 1 0 0 0 1 ethanolaminephosphotransferase activity 4305 1 0 0 0 1 ethanolamine kinase activity 4304 1 0 0 0 1 estrone sulfotransferase activity 4303 4 0 0 0 1 estradiol 17 beta-dehydrogenase activity 9197 1 0 0 0 1 pyrimidine deoxyribonucleoside diphosphate biosynthesis 9196 1 0 0 0 1 pyrimidine deoxyribonucleoside diphosphate metabolism 9191 3 0 0 0 1 ribonucleoside diphosphate catabolism 9190 10 0 0 0 1 cyclic nucleotide biosynthesis 9189 1 0 0 0 1 deoxyribonucleoside diphosphate biosynthesis 9187 12 0 0 0 1 cyclic nucleotide metabolism 9186 2 0 0 0 1 deoxyribonucleoside diphosphate metabolism 9185 3 0 0 0 1 ribonucleoside diphosphate metabolism 9181 3 0 0 0 1 purine ribonucleoside diphosphate catabolism 9179 3 0 0 0 1 purine ribonucleoside diphosphate metabolism 9177 1 0 0 0 1 pyrimidine deoxyribonucleoside monophosphate biosynthesis 9176 1 0 0 0 1 pyrimidine deoxyribonucleoside monophosphate metabolism 9169 1 0 0 0 1 purine ribonucleoside monophosphate catabolism 9166 8 0 0 0 1 nucleotide catabolism 9162 1 0 0 0 1 deoxyribonucleoside monophosphate metabolism 9158 1 0 0 0 1 ribonucleoside monophosphate catabolism 9157 1 0 0 0 1 deoxyribonucleoside monophosphate biosynthesis 9155 1 0 0 0 1 purine deoxyribonucleotide catabolism 9154 4 0 0 0 1 purine ribonucleotide catabolism 9151 1 0 0 0 1 purine deoxyribonucleotide metabolism 9148 2 0 0 0 1 pyrimidine nucleoside triphosphate biosynthesis 9146 2 0 0 0 1 purine nucleoside triphosphate catabolism 9143 2 0 0 0 1 nucleoside triphosphate catabolism 9139 1 0 0 0 1 pyrimidine nucleoside diphosphate biosynthesis 9138 1 0 0 0 1 pyrimidine nucleoside diphosphate metabolism 9137 3 0 0 0 1 purine nucleoside diphosphate catabolism 9135 3 0 0 0 1 purine nucleoside diphosphate metabolism 9134 3 0 0 0 1 nucleoside diphosphate catabolism 9133 1 0 0 0 1 nucleoside diphosphate biosynthesis 9132 5 0 0 0 1 nucleoside diphosphate metabolism 9130 1 0 0 0 1 pyrimidine nucleoside monophosphate biosynthesis 9129 1 0 0 0 1 pyrimidine nucleoside monophosphate metabolism 9128 1 0 0 0 1 purine nucleoside monophosphate catabolism 9125 1 0 0 0 1 nucleoside monophosphate catabolism 9120 1 0 0 0 1 deoxyribonucleoside metabolism 9113 1 0 0 0 1 purine base biosynthesis 9112 9 0 0 1 1 nucleobase metabolism 9110 1 0 0 0 1 vitamin biosynthesis 9107 1 0 0 0 1 lipoate biosynthesis 9106 1 0 0 0 1 lipoate metabolism 9105 1 0 0 0 1 lipoic acid biosynthesis 9103 1 0 0 0 1 lipopolysaccharide biosynthesis 9102 1 0 0 0 1 biotin biosynthesis 42596 3 0 0 0 1 fear response 42594 1 0 0 0 1 response to starvation 42575 3 0 0 0 1 DNA polymerase complex 42574 3 0 0 0 1 retinal metabolism 30595 4 0 0 0 1 immune cell chemotaxis 30594 38 0 0 0 1 neurotransmitter receptor activity 30593 2 0 0 0 1 neutrophil chemotaxis 42562 1 0 0 0 1 hormone binding 16299 1 0 0 0 1 regulator of G-protein signaling activity 16298 34 0 0 6 1 lipase activity 42554 2 0 0 0 1 superoxide release 16291 1 0 0 0 1 acyl-CoA thioesterase activity 30578 1 0 0 0 1 PML body organization and biogenesis 30575 1 0 0 0 1 nuclear body organization and biogenesis 30573 1 0 0 0 1 bile acid catabolism 16289 2 0 0 0 1 CoA hydrolase activity 16286 4 0 0 0 1 small conductance calcium-activated potassium channel activity 16281 1 0 0 0 1 eukaryotic translation initiation factor 4F complex 42537 1 0 0 0 1 benzene and derivative metabolism 16271 4 0 0 0 1 tissue death 4297 1 0 0 0 1 U-plasminogen activator activity 30553 5 0 0 0 1 "3',5'-cGMP binding" 4296 1 0 0 0 1 T-plasminogen activator activity 30552 8 0 0 1 1 "3',5'-cAMP binding" 4294 1 0 0 0 1 tripeptidyl-peptidase II activity 4293 5 0 0 1 1 tissue kallikrein activity 4289 15 0 0 0 1 subtilase activity 4287 4 0 0 0 1 prolyl oligopeptidase activity 4286 1 0 0 0 1 proprotein convertase 2 activity 4285 1 0 0 0 1 proprotein convertase 1 activity 4284 1 0 0 0 1 acrosin activity 4283 1 0 0 0 1 plasmin activity 4281 1 0 0 0 1 pancreatic elastase II activity 16251 25 0 0 4 1 general RNA polymerase II transcription factor activity 30539 4 0 0 0 1 male genital morphogenesis 30538 4 0 0 0 1 genital morphogenesis 30537 2 0 0 0 1 larval behavior 30536 1 0 0 0 1 larval feeding behavior 4278 1 0 0 0 1 granzyme B activity 4277 1 0 0 0 1 granzyme A activity 4276 1 0 0 0 1 furin activity 4275 1 0 0 0 1 enteropeptidase activity 4274 3 0 0 0 1 dipeptidyl-peptidase IV activity 16247 4 0 0 0 1 channel regulator activity 16245 1 0 0 0 1 hyperphosphorylation of RNA polymerase II 30523 1 0 0 0 1 dihydrolipoamide S-acyltransferase activity 4261 1 0 0 0 1 cathepsin G activity 16235 1 0 0 0 1 aggresome 16234 1 0 0 0 1 inclusion body 30519 1 0 0 0 1 snoRNP binding 30517 2 0 0 0 1 negative regulation of axon extension 30516 2 0 0 0 1 regulation of axon extension 30514 1 0 0 0 1 negative regulation of BMP signaling pathway 30512 1 0 0 0 1 negative regulation of TGFbeta receptor signaling pathway 4254 1 0 0 0 1 acylaminoacyl-peptidase activity 30510 1 0 0 0 1 regulation of BMP signaling pathway 4251 1 0 0 0 1 Xaa-Pro dipeptidase activity 16229 8 0 0 0 1 steroid dehydrogenase activity 16226 1 0 0 0 1 iron-sulfur cluster assembly 16225 2 0 0 0 1 cysteine desulfhydrase activity 16220 1 0 0 0 1 RAL GDP-dissociation stimulator activity 30509 3 0 0 0 1 BMP receptor signaling pathway 4249 1 0 0 0 1 stromelysin 3 activity 4248 1 0 0 0 1 stromelysin 1 activity 4246 2 0 0 0 1 peptidyl-dipeptidase A activity 30502 1 0 0 0 1 negative regulation of bone mineralization 4245 4 0 0 0 1 neprilysin activity 30500 1 0 0 0 1 regulation of bone mineralization 4243 1 0 0 0 1 mitochondrial intermediate peptidase activity 4240 1 0 0 0 1 mitochondrial processing peptidase activity 16219 1 0 0 0 1 GDP-dissociation stimulator activity 4239 4 0 0 0 1 methionyl aminopeptidase activity 4238 2 0 0 0 1 meprin A activity 4237 2 0 0 0 1 membrane dipeptidase activity 4235 1 0 0 0 1 matrilysin activity 4234 1 0 0 0 1 macrophage elastase activity 4232 1 0 0 0 1 interstitial collagenase activity 4230 1 0 0 0 1 glutamyl aminopeptidase activity 16208 8 0 0 1 1 AMP binding 16203 2 0 0 0 1 muscle attachment 16202 3 0 0 0 1 regulation of myogenesis 4229 1 0 0 0 1 gelatinase B activity 4228 1 0 0 0 1 gelatinase A activity 4226 1 0 0 0 1 gly-X carboxypeptidase activity 4218 1 0 0 0 1 cathepsin S activity 4216 1 0 0 0 1 cathepsin K activity 4208 1 0 0 0 1 caspase-3 activity 4205 1 0 0 0 1 caspase-8 activity 9093 2 0 0 0 1 cysteine catabolism 9092 1 0 0 0 1 homoserine metabolism 9086 6 0 0 0 1 methionine biosynthesis 9077 3 0 0 0 1 histidine family amino acid catabolism 9076 2 0 0 0 1 histidine family amino acid biosynthesis 9075 5 0 0 0 1 histidine family amino acid metabolism 9071 3 0 0 0 1 serine family amino acid catabolism 9068 1 0 0 0 1 aspartate family amino acid catabolism 9067 7 0 0 0 1 aspartate family amino acid biosynthesis 9066 9 0 0 0 1 aspartate family amino acid metabolism 9065 6 0 0 1 1 glutamine family amino acid catabolism 9064 22 0 0 4 1 glutamine family amino acid metabolism 9062 1 0 0 0 1 fatty acid catabolism 9055 17 0 0 3 1 electron carrier activity 9052 1 0 0 0 1 "pentose-phosphate shunt, non-oxidative branch" 9048 1 0 0 0 1 "dosage compensation, by inactivation of X chromosome" 9045 1 0 0 0 1 xylose isomerase activity 9008 2 0 0 0 1 DNA-methyltransferase activity 42493 8 0 0 1 1 response to drug 42491 3 0 0 0 1 hair cell differentiation 42490 3 0 0 0 1 mechanoreceptor differentiation 42476 1 0 0 0 1 odontogenesis 42475 1 0 0 0 1 odontogenesis (sensu Vertebrata) 42472 4 0 0 0 1 inner ear morphogenesis 42471 4 0 0 0 1 ear morphogenesis 30497 2 0 0 0 1 fatty acid elongation 30492 2 0 0 0 1 hemoglobin binding 30491 1 0 0 0 1 heteroduplex formation 30490 2 0 0 0 1 processing of 20S pre-rRNA 42462 8 0 0 1 1 eye photoreceptor cell development 42461 9 0 0 1 1 photoreceptor cell development 30489 2 0 0 0 1 processing of 27S pre-rRNA 30484 34 0 0 0 1 muscle fiber 30482 2 0 0 0 1 actin cable (sensu Fungi) 16194 8 0 0 1 1 nonselective vesicle exocytosis 30479 3 0 0 0 1 actin cortical patch (sensu Fungi) 30478 5 0 0 1 1 actin cap (sensu Fungi) 30474 1 0 0 0 1 spindle pole body duplication (sensu Fungi) 30473 1 0 0 0 1 nuclear migration (sensu Fungi) 42448 1 0 0 0 1 progesterone metabolism 42446 13 0 0 2 1 hormone biosynthesis 42441 1 0 0 0 1 eye pigment metabolism 16183 1 0 0 0 1 synaptic vesicle coating 16181 14 0 0 2 1 synaptic vesicle transport 16180 1 0 0 0 1 snRNA processing 30466 2 0 0 0 1 chromatin silencing at silent mating type cassettes (sensu Fungi) 42439 2 0 0 0 1 ethanolamine and derivative metabolism 42438 6 0 0 0 1 melanin biosynthesis 42436 1 0 0 0 1 indole derivative catabolism 16175 3 0 0 0 1 superoxide-generating NADPH oxidase activity 16174 3 0 0 0 1 NADPH oxidase activity 4199 6 0 0 1 1 caspase activity 4195 1 0 0 0 1 renin activity 4194 5 0 0 1 1 pepsin A activity 4193 1 0 0 0 1 cathepsin E activity 42428 1 0 0 0 1 serotonin metabolism 42427 1 0 0 0 1 serotonin biosynthesis 4190 7 0 0 1 1 aspartic-type endopeptidase activity 42423 3 0 0 0 1 catecholamine biosynthesis 16165 7 0 0 0 1 lipoxygenase activity 16160 4 0 0 0 1 amylase activity 4187 2 0 0 0 1 carboxypeptidase D activity 4186 2 0 0 0 1 carboxypeptidase C activity 4185 5 0 0 1 1 serine carboxypeptidase activity 4183 1 0 0 0 1 carboxypeptidase H activity 4181 12 0 0 2 1 metallocarboxypeptidase activity 42417 5 0 0 1 1 dopamine metabolism 42416 3 0 0 0 1 dopamine biosynthesis 16151 1 0 0 0 1 nickel ion binding 30433 1 0 0 0 1 ER-associated protein catabolism 30432 1 0 0 0 1 peristalsis 4176 2 0 0 0 1 ATP-dependent peptidase activity 4174 1 0 0 0 1 electron-transferring-flavoprotein dehydrogenase activity 42403 2 0 0 0 1 thyroid hormone metabolism 42401 10 0 0 1 1 biogenic amine biosynthesis 30429 1 0 0 0 1 kynureninase activity 30425 1 0 0 0 1 dendrite 30424 4 0 0 0 1 axon 4167 1 0 0 0 1 dopachrome delta-isomerase activity 4165 1 0 0 0 1 dodecenoyl-CoA delta-isomerase activity 4163 1 0 0 0 1 diphosphomevalonate decarboxylase activity 4158 1 0 0 0 1 dihydroorotate oxidase activity 4157 1 0 0 0 1 dihydropyrimidinase activity 30412 1 0 0 0 1 formimidoyltetrahydrofolate cyclodeaminase activity 4155 1 0 0 0 1 dihydropteridine reductase activity 4152 1 0 0 0 1 dihydroorotate dehydrogenase activity 16127 1 0 0 0 1 sterol catabolism 30409 1 0 0 0 1 glutamate formimidoyltransferase activity 30407 1 0 0 0 1 formiminotransferase activity 4146 1 0 0 0 1 dihydrofolate reductase activity 4144 1 0 0 0 1 diacylglycerol O-acyltransferase activity 4143 6 0 0 0 1 diacylglycerol kinase activity 16117 1 0 0 0 1 carotenoid biosynthesis 16116 1 0 0 0 1 carotenoid metabolism 16114 1 0 0 0 1 terpenoid biosynthesis 4138 1 0 0 0 1 deoxyguanosine kinase activity 4137 1 0 0 0 1 deoxycytidine kinase activity 16109 1 0 0 0 1 tetraterpenoid biosynthesis 16108 1 0 0 0 1 tetraterpenoid metabolism 4126 2 0 0 0 1 cytidine deaminase activity 4123 1 0 0 0 1 cystathionine-gamma-lyase activity 4122 1 0 0 0 1 cystathione beta-synthase activity 4121 1 0 0 0 1 cystathionine beta-lyase activity 4119 1 0 0 0 1 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity 4118 1 0 0 0 1 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity 4116 3 0 0 0 1 cGMP-specific phosphodiesterase activity 4115 5 0 0 1 1 cAMP-specific phosphodiesterase activity 4109 1 0 0 0 1 coproporphyrinogen oxidase activity 4108 1 0 0 0 1 citrate (SI)-synthase activity 4104 3 0 0 0 1 cholinesterase activity 4103 2 0 0 0 1 choline kinase activity 4102 1 0 0 0 1 choline O-acetyltransferase activity 4100 1 0 0 0 1 chitin synthase activity 42396 2 0 0 0 1 phosphagen biosynthesis 42393 3 0 0 0 1 histone binding 42392 1 0 0 0 1 sphingosine-1-phosphate phosphatase activity 42391 4 0 0 0 1 regulation of membrane potential 42379 26 0 0 4 1 chemokine receptor binding 42375 3 0 0 0 1 quinone cofactor metabolism 42364 1 0 0 0 1 water-soluble vitamin biosynthesis 42360 1 0 0 0 1 vitamin E metabolism 30389 1 0 0 0 1 fructosamine metabolism 30387 1 0 0 0 1 fructosamine-3-kinase activity 30384 11 0 0 2 1 phosphoinositide metabolism 30381 1 0 0 0 1 eggshell pattern formation (sensu Insecta) 30380 1 0 0 0 1 interleukin-17E receptor binding 16096 1 0 0 0 1 polyisoprenoid metabolism 30377 1 0 0 0 1 U-plasminogen activator receptor activity 30374 1 0 0 0 1 ligand-dependent nuclear receptor transcription co-activator activity 30371 1 0 0 0 1 translation repressor activity 42348 1 0 0 0 1 NF-kappaB protein-nucleus import 42346 1 0 0 0 1 positive regulation of NF-kappaB protein-nucleus import 42345 1 0 0 0 1 regulation of NF-kappaB protein-nucleus import 16087 1 0 0 0 1 ecdysiostatic hormone activity 16086 1 0 0 0 1 allatostatin 16085 1 0 0 0 1 myoinhibitory hormone activity 16083 2 0 0 0 1 synaptic vesicle fusion 16081 5 0 0 1 1 synaptic vesicle docking 30364 1 0 0 0 1 cleavage/polyadenylation specificity factor activity 30363 1 0 0 0 1 pre-mRNA cleavage factor activity 42331 1 0 0 0 1 phototaxis 16074 1 0 0 0 1 snoRNA metabolism 16071 21 0 0 3 1 mRNA metabolism 4098 1 0 0 0 1 cerebroside-sulfatase activity 4095 2 0 0 0 1 carnitine O-palmitoyltransferase activity 30350 1 0 0 0 1 iron-responsive element binding 4092 1 0 0 0 1 carnitine O-acetyltransferase activity 4091 9 0 0 1 1 carboxylesterase activity 16066 4 0 0 0 1 cellular defense response (sensu Vertebrata) 16065 5 0 0 1 1 humoral defense mechanism (sensu Invertebrata) 4089 6 0 0 1 1 carbonate dehydratase activity 30345 1 0 0 0 1 structural constituent of tooth enamel 4088 2 0 0 0 1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 4087 1 0 0 0 1 carbamoyl-phosphate synthase (ammonia) activity 4086 3 0 0 0 1 carbamoyl-phosphate synthase activity 4085 1 0 0 0 1 butyryl-CoA dehydrogenase activity 4081 1 0 0 0 1 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 16054 2 0 0 0 1 organic acid catabolism 16050 2 0 0 0 1 vesicle organization and biogenesis 30337 1 0 0 0 1 DNA polymerase processivity factor activity 30334 11 0 0 2 1 regulation of cell migration 4077 1 0 0 0 1 biotin-[acetyl-CoA-carboxylase] ligase activity 4075 2 0 0 0 1 biotin carboxylase activity 42307 1 0 0 0 1 positive regulation of protein-nucleus import 42306 2 0 0 0 1 regulation of protein-nucleus import 42302 3 0 0 0 1 structural constituent of cuticle 4067 1 0 0 0 1 asparaginase activity 4066 1 0 0 0 1 asparagine synthase (glutamine-hydrolyzing) activity 30322 1 0 0 0 1 stabilization of membrane potential 4065 3 0 0 0 1 arylsulfatase activity 4064 3 0 0 0 1 arylesterase activity 16034 1 0 0 0 1 maleylacetoacetate isomerase activity 30318 2 0 0 0 1 melanocyte differentiation 30316 1 0 0 0 1 osteoclast differentiation 30315 1 0 0 0 1 T-tubule 4058 1 0 0 0 1 aromatic-L-amino acid decarboxylase activity 4053 2 0 0 0 1 arginase activity 4052 2 0 0 0 1 arachidonate 12-lipoxygenase activity 4051 1 0 0 0 1 arachidonate 5-lipoxygenase activity 4050 2 0 0 0 1 apyrase activity 30308 6 0 0 0 1 negative regulation of cell growth 30307 1 0 0 0 1 positive regulation of cell growth 30305 1 0 0 0 1 heparanase activity 4047 1 0 0 0 1 aminomethyltransferase activity 4046 2 0 0 0 1 aminoacylase activity 30301 3 0 0 0 1 cholesterol transport 30300 3 0 0 0 1 regulation of cholesterol absorption 4042 1 0 0 0 1 amino acid N-acetyltransferase activity 4041 2 0 0 0 1 amine oxidase (flavin-containing) activity 4040 1 0 0 0 1 amidase activity 16019 1 0 0 0 1 peptidoglycan recognition activity 16013 2 0 0 0 1 syntrophin complex 16012 2 0 0 0 1 sarcoglycan complex 16011 3 0 0 0 1 dystroglycan complex 16010 5 0 0 0 1 dystrophin-associated glycoprotein complex 4037 1 0 0 0 1 allantoicase activity 4035 1 0 0 0 1 alkaline phosphatase activity 4031 1 0 0 0 1 aldehyde oxidase activity 16005 1 0 0 0 1 phospholipase A2 activator activity 16004 1 0 0 0 1 phospholipase activator activity 16000 2 0 0 0 1 iota DNA polymerase activity 19991 1 0 0 0 1 septate junction assembly 4026 2 0 0 0 1 alcohol O-acetyltransferase activity 4021 1 0 0 0 1 alanine aminotransferase activity 4020 1 0 0 0 1 adenylylsulfate kinase activity 19988 1 0 0 0 1 charged-tRNA modification 19986 2 0 0 0 1 "deoxycytidyl transferase activity, template dependent" 19984 2 0 0 0 1 sigma DNA polymerase activity 4019 1 0 0 0 1 adenylosuccinate synthase activity 4016 7 0 0 0 1 adenylate cyclase activity 4015 2 0 0 0 1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity 4014 1 0 0 0 1 adenosylmethionine decarboxylase activity 4012 1 0 0 0 1 phospholipid-translocating ATPase activity 4008 2 0 0 0 1 copper-exporting ATPase activity 4001 1 0 0 0 1 adenosine kinase activity 4000 5 0 0 1 1 adenosine deaminase activity 19969 1 0 0 0 1 interleukin-10 binding 19968 1 0 0 0 1 "interleukin-1, Type II, blocking binding" 19967 10 0 0 0 1 "interleukin-1, Type I, activating binding" 19966 11 0 0 0 1 interleukin-1 binding 19962 1 0 0 0 1 interferon-alpha/beta binding 19961 1 0 0 0 1 interferon binding 19959 1 0 0 0 1 interleukin-8 binding 19958 5 0 0 0 1 C-X-C chemokine binding 19957 12 0 0 0 1 C-C chemokine binding 19956 18 0 0 0 1 chemokine binding 19950 1 0 0 0 1 SMT3-dependent protein catabolism 19948 1 0 0 0 1 SUMO activating enzyme activity 19943 1 0 0 0 1 RUB1-protein conjugation 19942 1 0 0 0 1 RUB1-dependent protein catabolism 19934 3 0 0 0 1 cGMP-mediated signaling 19914 1 0 0 0 1 "cyclin-dependent protein kinase activating kinase, regulator activity" 19912 1 0 0 0 1 cyclin-dependent protein kinase activating kinase activity 19911 1 0 0 0 1 structural constituent of myelin sheath 19905 2 0 0 0 1 syntaxin binding 19903 1 0 0 0 1 protein phosphatase binding 19902 1 0 0 0 1 phosphatase binding 19901 2 0 0 0 1 protein kinase binding 19900 2 0 0 0 1 kinase binding 42287 2 0 0 0 1 MHC protein binding 42285 1 0 0 0 1 xylosyltransferase activity 30299 3 0 0 0 1 cholesterol absorption 30296 1 0 0 0 1 protein tyrosine kinase activator activity 30295 2 0 0 0 1 protein kinase activator activity 30285 2 0 0 0 1 integral to synaptic vesicle membrane 30282 4 0 0 0 1 bone mineralization 30279 1 0 0 0 1 negative regulation of bone formation 30278 2 0 0 0 1 regulation of bone formation 30277 1 0 0 0 1 maintenance of gastrointestinal epithelium 30276 3 0 0 0 1 clathrin binding 30261 12 0 0 2 1 chromosome condensation 30250 1 0 0 0 1 guanylate cyclase activator activity 42226 1 0 0 0 1 interleukin-6 biosynthesis 30249 1 0 0 0 1 guanylate cyclase regulator activity 30247 1 0 0 0 1 polysaccharide binding 30246 43 0 0 0 1 carbohydrate binding 42214 1 0 0 0 1 terpene metabolism 30239 2 0 0 0 1 myofibril assembly 30238 1 0 0 0 1 male sex determination 30224 1 0 0 0 1 monocyte differentiation 30222 1 0 0 0 1 eosinophil differentiation 30220 1 0 0 0 1 platelet formation 30218 4 0 0 0 1 erythrocyte differentiation 30217 1 0 0 0 1 T-cell differentiation 30216 2 0 0 0 1 keratinocyte differentiation 30206 1 0 0 0 1 chondroitin sulfate biosynthesis 30204 1 0 0 0 1 chondroitin sulfate metabolism 30203 4 0 0 0 1 glycosaminoglycan metabolism 30202 1 0 0 0 1 heparin metabolism 30201 5 0 0 0 1 heparan sulfate proteoglycan metabolism 19899 5 0 0 0 1 enzyme binding 19886 2 0 0 0 1 "antigen processing, exogenous antigen via MHC class II" 19884 1 0 0 0 1 "antigen presentation, exogenous antigen" 19864 2 0 0 0 1 IgG binding 19861 3 0 0 0 1 flagellum 19856 2 0 0 0 1 pyrimidine base biosynthesis 19841 4 0 0 0 1 retinol binding 19840 6 0 0 0 1 isoprenoid binding 19835 7 0 0 0 1 cytolysis 19827 1 0 0 0 1 stem cell maintenance 19825 11 0 0 2 1 oxygen binding 19807 1 0 0 0 1 aspartoacylase activity 42178 1 0 0 0 1 xenobiotic catabolism 42177 1 0 0 0 1 negative regulation of protein catabolism 42176 1 0 0 0 1 regulation of protein catabolism 30199 1 0 0 0 1 collagen fibril organization 30198 9 0 0 1 1 extracellular matrix organization and biogenesis 30195 2 0 0 0 1 negative regulation of blood coagulation 30193 2 0 0 0 1 regulation of blood coagulation 42168 15 0 0 2 1 heme metabolism 42166 1 0 0 0 1 acetylcholine binding 42165 38 0 0 0 1 neurotransmitter binding 42162 3 0 0 0 1 telomeric DNA binding 30183 1 0 0 0 1 B-cell differentiation 42156 1 0 0 0 1 zinc-mediated transcriptional activator activity 30178 1 0 0 0 1 negative regulation of Wnt receptor signaling pathway 30177 1 0 0 0 1 positive regulation of Wnt receptor signaling pathway 30176 2 0 0 0 1 integral to endoplasmic reticulum membrane 42148 1 0 0 0 1 strand invasion 30168 3 0 0 0 1 platelet activation 30166 6 0 0 0 1 proteoglycan biosynthesis 30162 1 0 0 0 1 regulation of proteolysis and peptidolysis 30160 1 0 0 0 1 GKAP/Homer scaffold activity 42138 2 0 0 0 1 meiotic DNA double-strand break formation 42136 6 0 0 0 1 neurotransmitter biosynthesis 42135 6 0 0 1 1 neurotransmitter catabolism 42134 1 0 0 0 1 rRNA primary transcript binding 42132 2 0 0 0 1 fructose-bisphosphatase activity 30159 4 0 0 0 1 receptor signaling complex scaffold protein activity 30158 1 0 0 0 1 peptide O-xylosyltransferase activity 30155 2 0 0 0 1 regulation of cell adhesion 30151 2 0 0 0 1 molybdenum ion binding 42124 1 0 0 0 1 "1,3-beta-glucanosyltransferase activity" 42123 1 0 0 0 1 glucanosyltransferase activity 30146 1 0 0 0 1 diuresis 30140 2 0 0 0 1 trans-Golgi network transport vesicle 42113 6 0 0 0 1 B-cell activation 42110 6 0 0 0 1 T-cell activation 30139 6 0 0 1 1 endocytic vesicle 30137 3 0 0 0 1 COPI-coated vesicle 30133 6 0 0 1 1 transport vesicle 30132 1 0 0 0 1 clathrin coat of coated pit 30131 3 0 0 0 1 clathrin adaptor complex 30130 1 0 0 0 1 clathrin coat of trans-Golgi network vesicle 42100 1 0 0 0 1 B-cell proliferation 30121 1 0 0 0 1 AP-1 adaptor complex 30119 1 0 0 0 1 membrane coat adaptor complex 30116 1 0 0 0 1 glial cell line-derived neurotrophic factor receptor binding 19795 1 0 0 0 1 nonprotein amino acid biosynthesis 19794 2 0 0 0 1 nonprotein amino acid metabolism 19781 1 0 0 0 1 RUB1 activating enzyme activity 19751 2 0 0 0 1 polyol metabolism 19740 1 0 0 0 1 nitrogen utilization 19735 1 0 0 0 1 antimicrobial humoral response (sensu Vertebrata) 19730 8 0 0 1 1 antimicrobial humoral response 19720 4 0 0 0 1 Mo-molybdopterin cofactor metabolism 19717 7 0 0 1 1 synaptosome 42098 2 0 0 0 1 T-cell proliferation 42095 1 0 0 0 1 interferon-gamma biosynthesis 42093 1 0 0 0 1 T-helper cell differentiation 42088 1 0 0 0 1 T-helper 1 type immune response 42087 1 0 0 0 1 cell-mediated immune response 42084 1 0 0 0 1 5-methyltetrahydrofolate methyltransferase activity 42083 1 0 0 0 1 "5,10-methylenetetrahydrofolate-dependent methyltransferase activity" 30099 10 0 0 1 1 myeloid blood cell differentiation 42069 1 0 0 0 1 regulation of catecholamine metabolism 42064 1 0 0 0 1 cell adhesion receptor regulator activity 42063 4 0 0 0 1 gliogenesis 42060 1 0 0 0 1 wound healing 30089 2 0 0 0 1 phycobilisome 42059 1 0 0 0 1 negative regulation of EGF receptor signaling pathway 42058 2 0 0 0 1 regulation of EGF receptor signaling pathway 42055 3 0 0 0 1 neuronal lineage restriction 42054 1 0 0 0 1 histone methyltransferase activity 42053 1 0 0 0 1 regulation of dopamine metabolism 42051 7 0 0 1 1 eye photoreceptor development (sensu Drosophila) 30076 2 0 0 0 1 light-harvesting complex 30075 2 0 0 0 1 thylakoid (sensu Cyanobacteria) 30071 1 0 0 0 1 regulation of mitotic metaphase/anaphase transition 42044 10 0 0 1 1 fluid transport 42043 1 0 0 0 1 neurexin binding 30056 1 0 0 0 1 hemidesmosome 30050 1 0 0 0 1 vesicle transport along actin filament 30048 3 0 0 0 1 actin filament-based movement 30046 1 0 0 0 1 parallel actin filament bundle formation 30042 1 0 0 0 1 actin filament depolymerization 30037 1 0 0 0 1 cell cycle dependent actin filament reorganization 30029 46 0 0 8 1 actin filament-based process 30026 1 0 0 0 1 manganese ion homeostasis 30021 1 0 0 0 1 extracellular matrix structural constituent conferring compression resistance activity 30018 3 0 0 0 1 Z disc 30017 30 0 0 0 1 sarcomere 30016 31 0 0 0 1 myofibril 30015 2 0 0 0 1 CCR4-NOT core complex 30008 2 0 0 0 1 TRAPP 45927 1 0 0 0 1 positive regulation of growth 45926 2 0 0 0 1 negative regulation of growth 45924 1 0 0 0 1 regulation of female receptivity 45923 1 0 0 0 1 positive regulation of fatty acid metabolism 7638 2 0 0 0 1 mechanosensory behavior 7635 1 0 0 0 1 chemosensory behavior 7631 4 0 0 0 1 feeding behavior 7628 4 0 0 0 1 adult walking behavior 7627 1 0 0 0 1 larval behavior (sensu Insecta) 7620 1 0 0 0 1 copulation 7619 4 0 0 0 1 courtship behavior 7618 1 0 0 0 1 mating 7617 4 0 0 0 1 mating behavior 7616 1 0 0 0 1 long-term memory 7613 3 0 0 0 1 memory 7612 11 0 0 0 1 learning 7611 15 0 0 0 1 learning and/or memory 7609 2 0 0 0 1 mechanosensory perception 7608 5 0 0 0 1 olfaction 7605 12 0 0 2 1 hearing 7601 44 0 0 0 1 vision 45896 1 0 0 0 1 "regulation of transcription, mitotic" 45860 1 0 0 0 1 positive regulation of protein kinase activity 45841 1 0 0 0 1 negative regulation of mitotic metaphase/anaphase transition 45839 1 0 0 0 1 negative regulation of mitosis 7595 3 0 0 0 1 lactation 7590 1 0 0 0 1 fat body metabolism (sensu Insecta) 7589 1 0 0 0 1 fluid secretion 7588 4 0 0 0 1 excretion 7586 10 0 0 0 1 digestion 7585 9 0 0 0 1 respiratory gaseous exchange 19541 1 0 0 0 1 propionate metabolism 7566 2 0 0 0 1 embryo implantation 7565 4 0 0 0 1 pregnancy 7562 2 0 0 0 1 eclosion 19532 1 0 0 0 1 oxalate transport 19531 1 0 0 0 1 oxalate transporter activity 19530 2 0 0 0 1 taurine metabolism 7552 5 0 0 1 1 metamorphosis 7549 1 0 0 0 1 dosage compensation 7548 8 0 0 0 1 sex differentiation 7538 1 0 0 0 1 primary sex determination 7534 5 0 0 0 1 gene conversion at MAT locus 7533 6 0 0 0 1 mating-type switching/recombination 7532 1 0 0 0 1 "regulation of transcription, mating-type specific" 7531 7 0 0 0 1 mating-type determination 7530 10 0 0 0 1 sex determination 7529 2 0 0 0 1 establishment of synaptic specificity at neuromuscular junction 7528 6 0 0 0 1 neuromuscular junction development 7527 1 0 0 0 1 adult somatic muscle development 7525 1 0 0 0 1 somatic muscle development 7519 22 0 0 4 1 myogenesis 7515 17 0 0 0 1 lymph gland development 7509 1 0 0 0 1 mesoderm migration 7507 24 0 0 4 1 heart development 7506 1 0 0 0 1 gonadal mesoderm development 7500 1 0 0 0 1 mesoderm cell fate determination 45793 1 0 0 0 1 positive regulation of cell size 45786 3 0 0 0 1 negative regulation of cell cycle 45785 1 0 0 0 1 positive regulation of cell adhesion 45773 1 0 0 0 1 positive regulation of axon extension 45765 6 0 0 0 1 regulation of angiogenesis 45746 1 0 0 0 1 negative regulation of N receptor signaling pathway 45744 1 0 0 0 1 negative regulation of G-protein coupled receptor protein signaling pathway 45742 1 0 0 0 1 positive regulation of EGF receptor signaling pathway 45735 1 0 0 0 1 nutrient reservoir activity 7498 12 0 0 2 1 mesoderm development 7495 1 0 0 0 1 visceral mesoderm/endoderm interaction 7494 2 0 0 0 1 midgut development 7492 5 0 0 0 1 endoderm development 7487 1 0 0 0 1 analia morphogenesis (sensu Holometabola) 7483 1 0 0 0 1 genital disc metamorphosis 7480 2 0 0 0 1 leg morphogenesis (sensu Holometabola) 19452 2 0 0 0 1 L-cysteine catabolism to taurine 7479 2 0 0 0 1 leg disc proximal/distal pattern formation 7478 4 0 0 0 1 leg disc metamorphosis 7477 1 0 0 0 1 notum morphogenesis 7476 5 0 0 0 1 wing morphogenesis 7474 1 0 0 0 1 wing vein specification 7472 5 0 0 0 1 wing disc metamorphosis 45705 1 0 0 0 1 negative regulation of salivary gland determination 19448 2 0 0 0 1 L-cysteine catabolism 45704 1 0 0 0 1 regulation of salivary gland determination 19441 1 0 0 0 1 tryptophan catabolism to kynurenine 7469 1 0 0 0 1 antennal morphogenesis 7468 1 0 0 0 1 regulation of rhodopsin gene activity 7467 9 0 0 1 1 photoreceptor differentiation (sensu Drosophila) 7466 1 0 0 0 1 cone cell fate commitment (sensu Drosophila) 7465 1 0 0 0 1 R7 cell fate commitment 7462 1 0 0 0 1 R1/R6 cell fate commitment 19433 1 0 0 0 1 triacylglycerol catabolism 7459 2 0 0 0 1 photoreceptor fate commitment (sensu Drosophila) 7455 10 0 0 1 1 eye-antennal disc metamorphosis 7449 2 0 0 0 1 "proximal/distal pattern formation, imaginal disc" 7447 2 0 0 0 1 imaginal disc pattern formation 7446 1 0 0 0 1 imaginal disc growth 7443 1 0 0 0 1 Malpighian tubule morphogenesis 7442 1 0 0 0 1 hindgut morphogenesis 19413 5 0 0 0 1 acetate biosynthesis 7439 1 0 0 0 1 gut (ectodermal) morphogenesis 7438 1 0 0 0 1 oenocyte development 7435 6 0 0 0 1 salivary gland morphogenesis 7432 2 0 0 0 1 salivary gland determination 7431 9 0 0 0 1 salivary gland development 7430 1 0 0 0 1 "terminal branching of trachea, cytoplasmic projection extension (sensu Insecta)" 7427 1 0 0 0 1 tracheal cell migration (sensu Insecta) 7425 3 0 0 0 1 tracheal cell fate determination (sensu Insecta) 7424 10 0 0 0 1 tracheal system development (sensu Insecta) 7416 1 0 0 0 1 synaptogenesis 7403 1 0 0 0 1 glial cell fate determination 45668 1 0 0 0 1 negative regulation of osteoblast differentiation 45667 1 0 0 0 1 regulation of osteoblast differentiation 45666 1 0 0 0 1 positive regulation of neuron differentiation 45664 1 0 0 0 1 regulation of neuron differentiation 45662 1 0 0 0 1 negative regulation of myoblast differentiation 45661 1 0 0 0 1 regulation of myoblast differentiation 19395 9 0 0 1 1 fatty acid oxidation 19379 1 0 0 0 1 "sulfate assimilation, phosphoadenylyl sulfate reduction by a phosphoadenylyl-sulfate reductase (thioredoxin)" 19370 10 0 0 1 1 leukotriene biosynthesis 7398 6 0 0 1 1 ectoderm development 7392 1 0 0 0 1 initiation of dorsal closure 7391 12 0 0 2 1 dorsal closure 7390 1 0 0 0 1 germ-band shortening 7388 1 0 0 0 1 posterior compartment specification 7387 1 0 0 0 1 anterior compartment specification 7386 4 0 0 0 1 compartment specification 7380 1 0 0 0 1 "specification of segmental identity, head" 7379 10 0 0 0 1 segment specification 19344 2 0 0 0 1 cysteine biosynthesis 7369 10 0 0 1 1 gastrulation 7368 5 0 0 1 1 determination of left/right asymmetry 7367 1 0 0 0 1 segment polarity determination 7365 2 0 0 0 1 periodic partitioning 7352 1 0 0 0 1 zygotic determination of dorsal/ventral axis 7351 1 0 0 0 1 regional subdivision 7350 6 0 0 0 1 blastoderm segmentation 19321 1 0 0 0 1 pentose metabolism 7348 1 0 0 0 1 regulation of syncytial blastoderm mitotic cell cycle 7346 4 0 0 0 1 regulation of mitotic cell cycle 7341 2 0 0 0 1 penetration of zona pellucida 7340 2 0 0 0 1 acrosome reaction 7339 1 0 0 0 1 binding of sperm to zona pellucida 19307 2 0 0 0 1 mannose biosynthesis 7329 2 0 0 0 1 positive regulation of transcription from Pol II promoter by pheromones 7323 1 0 0 0 1 peptide pheromone maturation 7313 1 0 0 0 1 "maternal determination of dorsal/ventral axis, oocyte, soma encoded" 7311 1 0 0 0 1 "maternal determination of dorsal/ventral axis, oocyte, germ-line encoded" 7310 4 0 0 0 1 oocyte dorsal/ventral axis determination 7309 6 0 0 1 1 oocyte axis determination 7308 6 0 0 1 1 oocyte construction 7303 1 0 0 0 1 "cytoplasmic transport, nurse cell to oocyte" 7301 1 0 0 0 1 ring canal formation 7300 1 0 0 0 1 nurse cell/oocyte transport (sensu Insecta) 45596 2 0 0 0 1 negative regulation of cell differentiation 45571 1 0 0 0 1 negative regulation of imaginal disc growth 45570 1 0 0 0 1 regulation of imaginal disc growth 19279 1 0 0 0 1 methionine biosynthesis from L-homoserine via cystathione 7298 2 0 0 0 1 border cell migration (sensu Insecta) 7297 2 0 0 0 1 follicle cell migration (sensu Insecta) 45523 1 0 0 0 1 interleukin-27 receptor binding 7288 1 0 0 0 1 axoneme assembly 7286 7 0 0 0 1 spermatid development 7281 7 0 0 1 1 germ-cell development 7273 6 0 0 0 1 regulation of synapse 7272 5 0 0 1 1 ionic insulation of neurons by glial cells 7271 9 0 0 0 1 "synaptic transmission, cholinergic" 7270 12 0 0 0 1 nerve-nerve synaptic transmission 7263 2 0 0 0 1 nitric oxide mediated signal transduction 7262 2 0 0 0 1 STAT protein nuclear translocation 7260 2 0 0 0 1 tyrosine phosphorylation of STAT protein 19237 1 0 0 0 1 centromeric DNA binding 19233 4 0 0 0 1 perception of pain 7259 11 0 0 0 1 JAK-STAT cascade 7257 1 0 0 0 1 activation of JUNK 7256 1 0 0 0 1 activation of JUNKK 7254 12 0 0 2 1 JNK cascade 7252 2 0 0 0 1 I-kappaB phosphorylation 7250 1 0 0 0 1 activation of NF-kappaB-inducing kinase 7249 7 0 0 1 1 NIK-I-kappaB/NF-kappaB cascade 19214 3 0 0 0 1 surfactant activity 7231 1 0 0 0 1 osmosensory signaling pathway 19209 2 0 0 0 1 kinase activator activity 19206 6 0 0 0 1 nucleoside kinase activity 19203 6 0 0 0 1 carbohydrate phosphatase activity 7226 1 0 0 0 1 regulation of smoothened receptor by patched 7224 2 0 0 0 1 smoothened receptor signaling pathway 7223 15 0 0 0 1 frizzled-2 receptor signaling pathway 7222 7 0 0 0 1 frizzled receptor signaling pathway 7219 5 0 0 0 1 N receptor signaling pathway 7217 1 0 0 0 1 tachykinin signaling pathway 7216 3 0 0 0 1 metabotropic glutamate receptor signaling pathway 7215 7 0 0 1 1 glutamate signaling pathway 7214 16 0 0 0 1 gamma-aminobutyric acid signaling pathway 7210 2 0 0 0 1 serotonin receptor signaling pathway 7208 1 0 0 0 1 "serotonin receptor, phospholipase C activating pathway" 7206 1 0 0 0 1 "metabotropic glutamate receptor, phospholipase C activating pathway" 7205 6 0 0 0 1 protein kinase C activation 7204 6 0 0 0 1 cytosolic calcium ion concentration elevation 45498 1 0 0 0 1 sex comb development 45475 2 0 0 0 1 locomotor rhythm 45473 1 0 0 0 1 response to ethanol (sensu Insecta) 45471 1 0 0 0 1 response to ethanol 45468 1 0 0 0 1 regulation of R8 spacing 45467 1 0 0 0 1 R7 development 45466 2 0 0 0 1 R7 differentiation 45465 1 0 0 0 1 R8 differentiation 45463 1 0 0 0 1 R8 development 45453 1 0 0 0 1 bone resorption 45448 1 0 0 0 1 "mitotic cell cycle, embryonic" 45445 2 0 0 0 1 myoblast differentiation 7199 3 0 0 0 1 "G-protein signaling, coupled to cGMP nucleotide second messenger" 7193 5 0 0 0 1 "G-protein signaling, adenylate cyclase inhibiting pathway" 7192 1 0 0 0 1 "serotonin receptor, adenylate cyclase activating pathway" 7191 1 0 0 0 1 "dopamine receptor, adenylate cyclase activating pathway" 7190 8 0 0 0 1 adenylate cyclase activation 45426 3 0 0 0 1 quinone cofactor biosynthesis 19166 1 0 0 0 1 trans-2-enoyl-CoA reductase (NADPH) activity 7184 2 0 0 0 1 SMAD protein nuclear translocation 7183 4 0 0 0 1 SMAD protein heteromerization 7182 7 0 0 0 1 common-partner SMAD protein phosphorylation 7176 3 0 0 0 1 regulation of EGF receptor activity 7175 1 0 0 0 1 negative regulation of EGF receptor activity 7174 1 0 0 0 1 EGF receptor ligand processing 7173 7 0 0 1 1 EGF receptor signaling pathway 7171 1 0 0 0 1 transmembrane receptor protein tyrosine kinase activation (dimerization) 7170 1 0 0 0 1 transmembrane receptor protein tyrosine kinase ligand binding 7168 1 0 0 0 1 receptor guanylyl cyclase signaling pathway 7162 1 0 0 0 1 negative regulation of cell adhesion 7160 35 0 0 6 1 cell-matrix adhesion 19136 4 0 0 0 1 deoxynucleoside kinase activity 7151 5 0 0 1 1 sporulation (sensu Saccharomyces) 19120 3 0 0 0 1 "hydrolase activity, acting on acid halide bonds, in C-halide compounds" 7141 3 0 0 0 1 male meiosis I 7140 7 0 0 0 1 male meiosis 7136 1 0 0 0 1 meiotic prophase II 7135 1 0 0 0 1 meiosis II 19107 2 0 0 0 1 myristoyltransferase activity 19104 6 0 0 0 1 DNA N-glycosylase activity 19100 1 0 0 0 1 male germ-line sex determination 7129 3 0 0 0 1 synapsis 7117 5 0 0 1 1 bud growth 7113 4 0 0 0 1 endomitotic cell cycle 7112 1 0 0 0 1 male meiosis cytokinesis 7103 1 0 0 0 1 spindle pole body duplication (sensu Saccharomyces) 19098 4 0 0 0 1 reproductive behavior 19079 1 0 0 0 1 viral genome replication 7095 1 0 0 0 1 mitotic G2 checkpoint 7093 6 0 0 1 1 mitotic checkpoint 45329 2 0 0 0 1 carnitine biosynthesis 7090 1 0 0 0 1 regulation of S phase of mitotic cell cycle 45321 12 0 0 0 1 cell activation 45317 1 0 0 0 1 equator specification 19058 1 0 0 0 1 viral infectious cycle 45313 1 0 0 0 1 rhabdomere membrane biogenesis 7076 5 0 0 1 1 mitotic chromosome condensation 45309 1 0 0 0 1 phosphoprotein amino acid binding 45308 2 0 0 0 1 protein amino acid binding 7070 1 0 0 0 1 "negative regulation of transcription from Pol II promoter, mitotic" 7068 1 0 0 0 1 "negative regulation of transcription, mitotic" 7066 1 0 0 0 1 female meiosis sister chromatid cohesion 7065 1 0 0 0 1 male meiosis sister chromatid cohesion 7064 1 0 0 0 1 mitotic sister chromatid cohesion 7062 7 0 0 1 1 sister chromatid cohesion 7060 1 0 0 0 1 male meiosis chromosome segregation 19031 2 0 0 0 1 viral envelope 7059 25 0 0 4 1 chromosome segregation 7054 1 0 0 0 1 male meiosis I spindle assembly (sensu Animalia) 7053 1 0 0 0 1 male meiotic spindle assembly (sensu Animalia) 7050 15 0 0 2 1 cell cycle arrest 7044 1 0 0 0 1 cell-substrate junction assembly 7043 1 0 0 0 1 intercellular junction assembly 7039 2 0 0 0 1 vacuolar protein catabolism 7031 20 0 0 3 1 peroxisome organization and biogenesis 19002 5 0 0 0 1 GMP binding 7026 5 0 0 0 1 microtubule stabilization 7025 1 0 0 0 1 beta-tubulin folding 7024 1 0 0 0 1 alpha-tubulin folding 7023 1 0 0 0 1 post-chaperonin tubulin folding pathway 7016 2 0 0 0 1 cytoskeletal anchoring 7011 1 0 0 0 1 regulation of cytoskeleton 7008 1 0 0 0 1 outer mitochondrial membrane organization and biogenesis 7007 1 0 0 0 1 inner mitochondrial membrane organization and biogenesis 7006 1 0 0 0 1 mitochondrial membrane organization and biogenesis 7005 22 0 0 4 1 mitochondrion organization and biogenesis 45285 2 0 0 0 1 ubiquinol-cytochrome c reductase complex 45275 2 0 0 0 1 respiratory chain complex III 45254 2 0 0 0 1 pyruvate dehydrogenase complex 45251 3 0 0 0 1 electron transfer flavoprotein complex 45240 1 0 0 0 1 alpha-ketoglutarate dehydrogenase complex 45214 1 0 0 0 1 sarcomere organization 45213 1 0 0 0 1 neurotransmitter receptor metabolism 45211 5 0 0 1 1 postsynaptic membrane 45197 3 0 0 0 1 establishment and/or maintenance of epithelial cell polarity 45196 1 0 0 0 1 establishment and/or maintenance of neuroblast cell polarity 45190 1 0 0 0 1 isotype switching 45185 1 0 0 0 1 maintenance of protein localization 45180 1 0 0 0 1 basal cortex 45178 1 0 0 0 1 basal part of cell 45175 1 0 0 0 1 basal protein localization 45172 1 0 0 0 1 ring canal (sensu Drosophila) 45171 1 0 0 0 1 intercellular bridge 2009 12 0 0 2 1 morphogenesis of an epithelium 5997 1 0 0 0 1 xylulose metabolism 5991 1 0 0 0 1 trehalose metabolism 45160 1 0 0 0 1 myosin I 5989 1 0 0 0 1 lactose biosynthesis 5988 1 0 0 0 1 lactose metabolism 5984 2 0 0 0 1 disaccharide metabolism 5978 7 0 0 0 1 glycogen biosynthesis 5967 2 0 0 0 1 pyruvate dehydrogenase complex (sensu Eukarya) 45136 1 0 0 0 1 development of secondary sexual characteristics 45132 4 0 0 0 1 meiotic chromosome segregation 5954 4 0 0 0 1 calcium/calmodulin-dependent protein kinase complex 5952 7 0 0 1 1 cAMP-dependent protein kinase complex 45127 1 0 0 0 1 N-acetylglucosamine kinase activity 45125 8 0 0 0 1 bioactive lipid receptor activity 5947 1 0 0 0 1 alpha-ketoglutarate dehydrogenase complex (sensu Eukarya) 5946 1 0 0 0 1 "alpha, alpha-trehalose-phosphate synthase complex (UDP-forming)" 5942 7 0 0 0 1 1-phosphatidylinositol 3-kinase complex 45111 17 0 0 3 1 intermediate filament cytoskeleton 5938 16 0 0 3 1 cell cortex 5930 2 0 0 0 1 axoneme 5929 7 0 0 0 1 cilium 5922 11 0 0 0 1 connexon complex 5918 2 0 0 0 1 septate junction 5916 1 0 0 0 1 fascia adherens 5903 2 0 0 0 1 brush border 5902 1 0 0 0 1 microvillus 5892 2 0 0 0 1 nicotinic acetylcholine-gated receptor-channel complex 5891 15 0 0 0 1 voltage-gated calcium channel complex 45063 1 0 0 0 1 T-helper 1 cell differentiation 5889 2 0 0 0 1 hydrogen/potassium-exchanging ATPase complex 5888 2 0 0 0 1 proteoglycan integral to plasma membrane 5883 1 0 0 0 1 neurofilament 5882 17 0 0 3 1 intermediate filament 5881 5 0 0 0 1 cytoplasmic microtubule 5869 5 0 0 1 1 dynactin complex 5865 13 0 0 0 1 striated muscle thin filament 5863 11 0 0 0 1 striated muscle thick filament 5862 3 0 0 0 1 muscle thin filament tropomyosin 5861 7 0 0 0 1 troponin complex 5860 3 0 0 0 1 non-muscle myosin 5859 3 0 0 0 1 muscle myosin 5857 3 0 0 0 1 actin cortical patch (sensu Saccharomyces) 5851 2 0 0 0 1 eukaryotic translation initiation factor 2B complex 45028 34 0 0 0 1 "purinergic nucleotide receptor activity, G-protein coupled" 45026 2 0 0 0 1 plasma membrane fusion 45022 2 0 0 0 1 early endosome to late endosome transport 5849 1 0 0 0 1 mRNA cleavage factor complex 5845 1 0 0 0 1 mRNA cap complex 5844 1 0 0 0 1 polysome 45017 2 0 0 0 1 glycerolipid biosynthesis 45012 1 0 0 0 1 MHC class II receptor activity 45010 1 0 0 0 1 actin nucleation 45009 1 0 0 0 1 chitosome 45005 16 0 0 0 1 maintenance of fidelity during DNA dependent DNA replication 45003 2 0 0 0 1 double-strand break repair via synthesis-dependent strand annealing 45002 3 0 0 0 1 double-strand break repair via single-strand annealing 5816 4 0 0 0 1 spindle pole body 5811 1 0 0 0 1 lipid particle 5801 2 0 0 0 1 Golgi cis-face 938 1 0 0 0 1 GARP complex 904 10 0 0 1 1 cellular morphogenesis during differentiation 5796 1 0 0 0 1 Golgi lumen 5791 2 0 0 0 1 rough endoplasmic reticulum 5784 2 0 0 0 1 translocon 5782 5 0 0 1 1 peroxisomal matrix 5779 1 0 0 0 1 integral peroxisomal membrane 5778 7 0 0 1 1 peroxisomal membrane 5760 1 0 0 0 1 gamma DNA polymerase complex 5744 6 0 0 1 1 mitochondrial inner membrane pre-sequence translocase complex 5741 21 0 0 3 1 mitochondrial outer membrane 5721 2 0 0 0 1 centric heterochromatin 5720 8 0 0 1 1 nuclear heterochromatin 5718 5 0 0 1 1 nucleosome 5712 1 0 0 0 1 chiasma 5703 1 0 0 0 1 polytene chromosome puff 40018 1 0 0 0 1 positive regulation of body size 40016 2 0 0 0 1 embryonic cleavage 40015 1 0 0 0 1 negative regulation of body size 40014 5 0 0 0 1 regulation of body size 40011 1 0 0 0 1 locomotion 808 1 0 0 0 1 origin of replication recognition complex 5699 1 0 0 0 1 kinetochore 5686 1 0 0 0 1 snRNP U2 5679 1 0 0 0 1 nucleosome remodeling complex 5677 5 0 0 0 1 chromatin silencing complex 5674 1 0 0 0 1 transcription factor TFIIF complex 5673 2 0 0 0 1 transcription factor TFIIE complex 5669 12 0 0 2 1 transcription factor TFIID complex 5664 1 0 0 0 1 nuclear origin of replication recognition complex 5663 5 0 0 0 1 DNA replication factor C complex 5660 1 0 0 0 1 delta-DNA polymerase cofactor complex 5659 3 0 0 0 1 delta DNA polymerase complex 5658 1 0 0 0 1 alpha DNA polymerase:primase complex 5656 8 0 0 0 1 pre-replicative complex 5655 5 0 0 1 1 nucleolar ribonuclease P complex 5639 1 0 0 0 1 integral to nuclear inner membrane 5608 1 0 0 0 1 laminin-3 798 2 0 0 0 1 nuclear cohesin complex 795 3 0 0 0 1 synaptonemal complex 794 12 0 0 2 1 condensed nuclear chromosome 792 8 0 0 1 1 heterochromatin 786 17 0 0 3 1 nucleosome 784 1 0 0 0 1 "nuclear chromosome, telomeric region" 783 1 0 0 0 1 nuclear telomere cap complex 782 1 0 0 0 1 telomere cap complex 781 2 0 0 0 1 "chromosome, telomeric region" 739 1 0 0 0 1 DNA strand annealing activity 737 2 0 0 0 1 "DNA catabolism, endonucleolytic" 736 1 0 0 0 1 "double-strand break repair via single-strand annealing, removal of nonhomologous ends" 735 3 0 0 0 1 removal of nonhomologous ends 730 1 0 0 0 1 DNA recombinase assembly 727 3 0 0 0 1 double-strand break repair via break-induced replication 725 4 0 0 0 1 recombinational repair 724 4 0 0 0 1 double-strand break repair via homologous recombination 722 3 0 0 0 1 telomerase-independent telomere maintenance 709 2 0 0 0 1 meiotic joint molecule formation 707 1 0 0 0 1 meiotic DNA recombinase assembly 706 1 0 0 0 1 meiotic DNA double-strand break processing 702 1 0 0 0 1 oxidized base lesion DNA N-glycosylase activity 5588 3 0 0 0 1 collagen type V 5587 2 0 0 0 1 collagen type IV 5583 3 0 0 0 1 fibrillar collagen 5579 3 0 0 0 1 membrane attack complex 5548 3 0 0 0 1 phospholipid transporter activity 5542 7 0 0 0 1 folic acid binding 5541 21 0 0 3 1 acyl-CoA or acyl binding 5537 2 0 0 0 1 mannose binding 5536 1 0 0 0 1 glucose binding 5531 3 0 0 0 1 galactose binding lectin 5530 1 0 0 0 1 lectin 5529 42 0 0 0 1 sugar binding 5523 5 0 0 0 1 tropomyosin binding 5522 4 0 0 0 1 profilin binding 5519 1 0 0 0 1 cytoskeletal regulatory protein binding 5518 2 0 0 0 1 collagen binding 5505 2 0 0 0 1 heavy metal binding 5504 4 0 0 0 1 fatty acid binding 5501 6 0 0 0 1 retinoid binding 5499 1 0 0 0 1 vitamin D binding 5498 3 0 0 0 1 sterol carrier activity 5487 6 0 0 1 1 nucleocytoplasmic transporter activity 5486 3 0 0 0 1 t-SNARE activity 5485 2 0 0 0 1 v-SNARE activity 5484 7 0 0 0 1 SNAP receptor activity 5483 1 0 0 0 1 soluble NSF attachment protein activity 5452 7 0 0 0 1 inorganic anion exchanger activity 5451 3 0 0 0 1 monovalent cation:proton antiporter activity 5432 3 0 0 0 1 calcium:sodium antiporter activity 5427 3 0 0 0 1 proton-dependent oligopeptide transporter activity 5415 2 0 0 0 1 nucleoside:sodium symporter activity 5412 1 0 0 0 1 glucose:sodium symporter activity 5403 1 0 0 0 1 hydrogen:sugar symporter-transporter activity 5402 1 0 0 0 1 cation:sugar symporter activity 578 2 0 0 0 1 embryonic axis specification 12510 1 0 0 0 1 trans-Golgi network transport vesicle membrane 12506 8 0 0 0 1 vesicle membrane 5385 2 0 0 0 1 zinc ion transporter activity 5381 1 0 0 0 1 iron ion transporter activity 5372 1 0 0 0 1 water transporter activity 5369 1 0 0 0 1 taurine:sodium symporter activity 5368 1 0 0 0 1 taurine transporter activity 5360 1 0 0 0 1 insulin-responsive hydrogen:glucose transporter activity 5355 8 0 0 1 1 glucose transporter activity 5354 1 0 0 0 1 galactose transporter activity 5353 2 0 0 0 1 fructose transporter activity 5350 1 0 0 0 1 pyrimidine transporter activity 5345 1 0 0 0 1 purine transporter activity 5343 3 0 0 0 1 organic acid:sodium symporter activity 5337 3 0 0 0 1 nucleoside transporter activity 5335 1 0 0 0 1 serotonin:sodium symporter activity 5330 1 0 0 0 1 dopamine:sodium symporter activity 5329 1 0 0 0 1 dopamine transporter activity 5328 8 0 0 1 1 neurotransmitter:sodium symporter activity 5326 9 0 0 1 1 neurotransmitter transporter activity 5315 5 0 0 1 1 inorganic phosphate transporter activity 5313 1 0 0 0 1 glutamate transporter activity 5311 6 0 0 0 1 sodium:dicarboxylate/tricarboxylate symporter activity 5310 8 0 0 0 1 dicarboxylic acid transporter activity 5309 1 0 0 0 1 creatine:sodium symporter activity 5308 1 0 0 0 1 creatine transporter activity 5290 2 0 0 0 1 histidine transporter activity 5286 1 0 0 0 1 basic amino acid permease activity 5283 1 0 0 0 1 sodium:amino acid transporter activity 5276 2 0 0 0 1 hydrogen:vesicular amine antiporter activity 5272 12 0 0 2 1 sodium channel activity 5267 68 0 0 0 1 potassium channel activity 5262 41 0 0 0 1 calcium channel activity 5251 1 0 0 0 1 delayed rectifier potassium channel activity 5249 39 0 0 0 1 voltage-gated potassium channel activity 5248 8 0 0 0 1 voltage-gated sodium channel activity 5246 3 0 0 0 1 calcium channel regulator activity 5245 19 0 0 0 1 voltage-gated calcium channel activity 5243 11 0 0 0 1 gap-junction forming channel activity 5242 15 0 0 0 1 inward rectifier potassium channel activity 5237 1 0 0 0 1 inhibitory extracellular ligand-gated ion channel activity 5234 15 0 0 0 1 glutamate-gated ion channel activity 5232 2 0 0 0 1 serotonin-activated cation-selective channel activity 5231 36 0 0 0 1 excitatory extracellular ligand-gated ion channel activity 5230 58 0 0 0 1 extracellular ligand-gated ion channel activity 5223 1 0 0 0 1 intracellular cGMP activated cation channel activity 5221 2 0 0 0 1 intracellular cyclic nucleotide activated cation channel activity 5220 1 0 0 0 1 "inositol 1,4,5-triphosphate-sensitive calcium-release channel activity" 5214 3 0 0 0 1 structural constituent of cuticle (sensu Insecta) activity 339 1 0 0 0 1 RNA cap binding 307 1 0 0 0 1 cyclin-dependent protein kinase holoenzyme complex 305 1 0 0 0 1 response to oxygen radicals 303 1 0 0 0 1 response to superoxide 301 2 0 0 0 1 retrograde (vesicle recycling within Golgi) transport 300 3 0 0 0 1 peripheral membrane protein of membrane fraction 17196 1 0 0 0 1 N-terminal peptidyl-methionine acetylation 17177 2 0 0 0 1 alpha-glucosidase complex 17174 1 0 0 0 1 glycine N-methyltransferase activity 17172 1 0 0 0 1 cysteine dioxygenase activity 17169 4 0 0 0 1 CDP-alcohol phosphatidyltransferase activity 17160 1 0 0 0 1 Ral interactor activity 5185 2 0 0 0 1 neurohypophyseal hormone activity 5181 6 0 0 0 1 glycopeptide hormone 5180 14 0 0 0 1 peptide hormone 17158 1 0 0 0 1 regulation of calcium ion dependent exocytosis 17157 3 0 0 0 1 regulation of exocytosis 17156 3 0 0 0 1 calcium ion dependent exocytosis 17155 1 0 0 0 1 sodium:hydrogen antiporter regulator activity 17153 1 0 0 0 1 sodium:dicarboxylate symporter activity 5176 1 0 0 0 1 Neu/ErbB-2 receptor binding 5172 2 0 0 0 1 vascular endothelial growth factor receptor binding 5171 1 0 0 0 1 hepatocyte growth factor receptor binding 17149 1 0 0 0 1 protein biosynthesis inhibitor activity 17140 1 0 0 0 1 lipoic acid synthase activity 5166 1 0 0 0 1 neurotrophin p75 receptor binding 5165 1 0 0 0 1 neurotrophin receptor binding 5164 15 0 0 2 1 tumor necrosis factor receptor binding 5161 1 0 0 0 1 platelet-derived growth factor receptor binding 5160 5 0 0 0 1 transforming growth factor-beta receptor binding 17137 2 0 0 0 1 Rab interactor activity 17136 1 0 0 0 1 NAD-dependent histone deacetylase activity 17133 3 0 0 0 1 electron transfer flavoprotein complex (sensu Eukarya) 17132 1 0 0 0 1 cyclic nucleotide dependent guanyl-nucleotide exchange factor activity 5158 5 0 0 0 1 insulin receptor binding 17127 2 0 0 0 1 cholesterol transporter activity 17125 2 0 0 0 1 deoxycytidyl transferase activity 17120 1 0 0 0 1 polyphosphoinositide phosphatase activity 5149 6 0 0 0 1 interleukin-1 receptor binding 5147 1 0 0 0 1 oncostatin-M receptor binding 5146 1 0 0 0 1 leukemia inhibitory factor receptor binding 5144 1 0 0 0 1 interleukin-13 receptor binding 5143 1 0 0 0 1 interleukin-12 receptor binding 5140 1 0 0 0 1 interleukin-9 receptor binding 17119 4 0 0 0 1 Golgi transport complex 17114 1 0 0 0 1 wide-spectrum protease inhibitor activity 17113 1 0 0 0 1 dihydropyrimidine dehydrogenase activity 17112 1 0 0 0 1 Rab guanyl-nucleotide exchange factor activity 17110 1 0 0 0 1 nucleoside diphosphatase activity 5139 1 0 0 0 1 interleukin-7 receptor binding 5138 1 0 0 0 1 interleukin-6 receptor binding 5137 1 0 0 0 1 interleukin-5 receptor binding 5136 1 0 0 0 1 interleukin-4 receptor binding 5135 1 0 0 0 1 interleukin-3 receptor binding 5134 1 0 0 0 1 interleukin-2 receptor binding 5133 1 0 0 0 1 interferon-gamma receptor binding 5131 1 0 0 0 1 growth hormone receptor binding 17108 1 0 0 0 1 flap endonuclease activity 5129 1 0 0 0 1 granulocyte macrophage colony-stimulating factor receptor binding 5128 2 0 0 0 1 erythropoietin receptor binding 5126 25 0 0 0 1 hematopoietin/interferon-class (D200-domain) cytokine receptor binding 5112 1 0 0 0 1 Notch binding 5106 4 0 0 0 1 ephrin 5104 15 0 0 0 1 fibroblast growth factor receptor binding 5100 1 0 0 0 1 Rho GTPase activator activity 299 2 0 0 0 1 integral membrane protein of membrane fraction 290 1 0 0 0 1 deadenylation-dependent decapping 289 2 0 0 0 1 poly(A) tail shortening 288 4 0 0 0 1 "mRNA catabolism, deadenylation-dependent" 285 1 0 0 0 1 1-phosphatidylinositol-3-phosphate 5-kinase activity 273 1 0 0 0 1 lipoic acid metabolism 272 1 0 0 0 1 polysaccharide catabolism 268 2 0 0 0 1 peroxisome targeting sequence binding 266 1 0 0 0 1 mitochondrial fission 260 1 0 0 0 1 hydrogen-translocating V-type ATPase activity 255 1 0 0 0 1 allantoin metabolism 247 1 0 0 0 1 C-8 sterol isomerase activity 238 3 0 0 0 1 zygotene 232 1 0 0 0 1 nuclear interphase chromosome 212 1 0 0 0 1 meiotic spindle assembly 209 2 0 0 0 1 protein polyubiquitination 17087 1 0 0 0 1 mitochondrial processing peptidase complex 17085 1 0 0 0 1 response to insecticide 17080 1 0 0 0 1 sodium channel regulator activity 5099 3 0 0 0 1 Ras GTPase activator activity 5095 5 0 0 0 1 GTPase inhibitor activity 17068 1 0 0 0 1 glutamyl-tRNA(Gln) amidotransferase activity 17061 1 0 0 0 1 5'-methylthioadenosine phosphorylase activity 5089 5 0 0 0 1 Rho guanyl-nucleotide exchange factor activity 5085 36 0 0 6 1 guanyl-nucleotide exchange factor activity 17053 3 0 0 0 1 transcriptional repressor complex 17050 1 0 0 0 1 D-erythro-sphingosine kinase activity 5079 7 0 0 0 1 protein kinase A anchor protein activity 5078 1 0 0 0 1 MAP-kinase scaffold protein activity 5076 10 0 0 1 1 receptor signaling protein serine/threonine kinase signaling protein activity 5072 2 0 0 0 1 "TGFbeta receptor, cytoplasmic mediator activity" 5071 2 0 0 0 1 transmembrane receptor protein serine/threonine kinase signaling protein activity 5070 9 0 0 1 1 SH3/SH2 adaptor protein activity 17047 1 0 0 0 1 adrenocorticotropin-releasing hormone binding 17046 1 0 0 0 1 polypeptide hormone binding 5069 10 0 0 1 1 transmembrane receptor protein tyrosine kinase docking protein activity 17039 1 0 0 0 1 dipeptidyl-peptidase III activity 5053 1 0 0 0 1 peroxisome targeting signal-2 receptor activity 5051 2 0 0 0 1 peroxisome targeting signal receptor activity 17028 1 0 0 0 1 protein stabilization activity 17022 2 0 0 0 1 myosin binding 5046 2 0 0 0 1 KDEL sequence binding 5044 14 0 0 0 1 scavenger receptor activity 5042 1 0 0 0 1 netrin receptor activity 17016 1 0 0 0 1 Ras interactor activity 17015 4 0 0 0 1 regulation of TGFbeta receptor signaling pathway 5035 5 0 0 0 1 death receptor activity 5034 1 0 0 0 1 osmosensor activity 5032 1 0 0 0 1 "tumor necrosis factor receptor cell differentiation, type I" 5031 4 0 0 0 1 tumor necrosis factor receptor activity 17005 1 0 0 0 1 tyrosyl-DNA phosophodiesterase activity 17004 1 0 0 0 1 cytochrome biogenesis 5027 4 0 0 0 1 NGF/TNF (6 C-domain) receptor activity 5024 12 0 0 2 1 transforming growth factor-beta receptor activity 5021 1 0 0 0 1 vascular endothelial growth factor receptor activity 5010 1 0 0 0 1 insulin-like growth factor receptor activity 5008 1 0 0 0 1 hepatocyte growth factor receptor activity 5005 3 0 0 0 1 transmembrane-ephrin receptor activity 5003 11 0 0 0 1 ephrin receptor activity 8937 1 0 0 0 1 ferredoxin reductase activity 8907 1 0 0 0 1 integrase activity 188 1 0 0 0 1 inactivation of MAPK 186 2 0 0 0 1 activation of MAPKK 185 2 0 0 0 1 activation of MAPKKK 178 5 0 0 0 1 exosome (RNase complex) 177 4 0 0 0 1 cytoplasmic exosome (RNase complex) 176 4 0 0 0 1 nuclear exosome (RNase complex) 175 7 0 0 0 1 3'-5' exoribonuclease activity 165 18 0 0 3 1 MAPKKK cascade 164 1 0 0 0 1 protein phosphatase type 1 complex 156 1 0 0 0 1 two-component response regulator activity 155 4 0 0 0 1 two-component sensor molecule activity 150 2 0 0 0 1 recombinase activity 149 5 0 0 0 1 SNARE binding 147 3 0 0 0 1 actin cortical patch assembly 146 1 0 0 0 1 microfilament motor activity 143 5 0 0 1 1 actin cap (sensu Saccharomyces) 141 2 0 0 0 1 actin cable (sensu Saccharomyces) 137 1 0 0 0 1 Golgi cis cisterna 126 1 0 0 0 1 transcription factor TFIIIB complex 120 5 0 0 0 1 RNA polymerase I transcription factor complex 119 6 0 0 1 1 mediator complex 110 1 0 0 0 1 nucleotide excision repair factor 1 complex 106 1 0 0 0 1 biotin-apoprotein ligase activity 105 2 0 0 0 1 histidine biosynthesis 101 1 0 0 0 1 sulfur amino acid transport 100 1 0 0 0 1 S-methylmethionine transporter activity 8898 2 0 0 0 1 homocysteine S-methyltransferase activity 8897 1 0 0 0 1 holo-[acyl-carrier protein] synthase activity 48052 1 0 0 0 1 R1/R6 differentiation (sensu Drosophila) 48051 9 0 0 1 1 post-embryonic eye morphogenesis (sensu Drosophila) 48050 9 0 0 1 1 post-embryonic eye morphogenesis 48029 3 0 0 0 1 monosaccharide binding 48016 1 0 0 0 1 inositol phosphate-mediated signaling 48015 2 0 0 0 1 phosphoinositide-mediated signaling 48011 1 0 0 0 1 NGF receptor signaling pathway 48008 1 0 0 0 1 PDGF receptor signaling pathway 99 1 0 0 0 1 sulfur amino acid transporter activity 98 2 0 0 0 1 sulfur amino acid catabolism 97 8 0 0 0 1 sulfur amino acid biosynthesis 96 12 0 0 0 1 sulfur amino acid metabolism 92 1 0 0 0 1 mitotic anaphase B 89 3 0 0 0 1 mitotic metaphase 88 5 0 0 1 1 mitotic prophase 80 16 0 0 3 1 G1 phase of mitotic cell cycle 77 13 0 0 2 1 "DNA damage response, signal transduction resulting in cell cycle arrest" 76 8 0 0 1 1 DNA replication checkpoint 65 1 0 0 0 1 nuclear migration (sensu Saccharomyces) 59 7 0 0 1 1 "protein-nucleus import, docking" 53 1 0 0 0 1 argininosuccinate metabolism 52 1 0 0 0 1 citrulline metabolism 48 2 0 0 0 1 peptidyltransferase activity 41 22 0 0 4 1 transition metal ion transport 38 1 0 0 0 1 very-long-chain fatty acid metabolism 15999 2 0 0 0 1 eta DNA polymerase activity 15997 1 0 0 0 1 ubiquinone biosynthesis monooxygenase activity 28 1 0 0 0 1 ribosomal small subunit assembly and maintenance 14 2 0 0 0 1 single-stranded DNA specific endodeoxyribonuclease activity 12 3 0 0 0 1 single strand break repair 11 3 0 0 0 1 vacuole inheritance 3998 2 0 0 0 1 acylphosphatase activity 3997 3 0 0 0 1 acyl-CoA oxidase activity 5 2 0 0 0 1 ribosomal chaperone activity 3995 8 0 0 1 1 acyl-CoA dehydrogenase activity 3994 2 0 0 0 1 aconitate hydratase activity 2 5 0 0 1 1 mitochondrial genome maintenance 3993 8 0 0 0 1 acid phosphatase activity 1 4 0 0 0 1 mitochondrion inheritance 3990 2 0 0 0 1 acetylcholinesterase activity 3982 1 0 0 0 1 UTP-hexose-1-phosphate uridylyltransferase activity 15955 1 0 0 0 1 pyrimidine deoxyribonucleotide interconversion 15953 1 0 0 0 1 pyrimidine nucleotide interconversion 3979 1 0 0 0 1 UDP-glucose 6-dehydrogenase activity 3978 1 0 0 0 1 UDP-glucose 4-epimerase activity 3973 2 0 0 0 1 (S)-2-hydroxy-acid oxidase activity 15949 1 0 0 0 1 "nucleobase, nucleoside and nucleotide interconversion" 3969 5 0 0 1 1 RNA editase activity 3964 1 0 0 0 1 RNA-directed DNA polymerase activity 3960 2 0 0 0 1 NADPH:quinone reductase activity 15937 1 0 0 0 1 coenzyme A biosynthesis 15936 1 0 0 0 1 coenzyme A metabolism 15932 4 0 0 0 1 "nucleobase, nucleoside, nucleotide and nucleic acid transporter activity" 15931 4 0 0 0 1 "nucleobase, nucleoside, nucleotide and nucleic acid transport" 3959 1 0 0 0 1 NADPH dehydrogenase activity 3957 1 0 0 0 1 NAD(P)+ transhydrogenase (B-specific) activity 3956 2 0 0 0 1 NAD(P)+-arginine ADP-ribosyltransferase activity 3953 2 0 0 0 1 NAD+ nucleosidase activity 3950 2 0 0 0 1 NAD+ ADP-ribosyltransferase activity 15929 5 0 0 1 1 hexosaminidase activity 15927 1 0 0 0 1 trehalase activity 15926 4 0 0 0 1 glucosidase activity 15925 4 0 0 0 1 galactosidase activity 15924 1 0 0 0 1 mannosyl-oligosaccharide mannosidase activity 3948 1 0 0 0 1 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 3945 3 0 0 0 1 N-acetyllactosamine synthase activity 3943 1 0 0 0 1 N-acetylgalactosamine-4-sulfatase activity 3941 1 0 0 0 1 L-serine ammonia-lyase activity 3940 1 0 0 0 1 L-iduronidase activity 15918 3 0 0 0 1 sterol transport 15914 1 0 0 0 1 phospholipid transport 15909 1 0 0 0 1 long-chain fatty acid transport 15908 2 0 0 0 1 fatty acid transport 3928 23 0 0 4 1 RAB small monomeric GTPase activity 3920 2 0 0 0 1 GMP reductase activity 3918 5 0 0 1 1 DNA topoisomerase type II activity 3913 1 0 0 0 1 DNA photolyase activity 3912 1 0 0 0 1 DNA nucleotidylexotransferase activity 3910 3 0 0 0 1 DNA ligase (ATP) activity 3909 3 0 0 0 1 DNA ligase activity 3908 2 0 0 0 1 methylated-DNA-[protein]-cysteine S-methyltransferase activity 3905 1 0 0 0 1 alkylbase DNA N-glycosylase activity 8796 2 0 0 0 1 bis(5'-nucleosyl)-tetraphosphatase activity 8794 1 0 0 0 1 arsenate reductase (glutaredoxin) activity 8781 1 0 0 0 1 acylneuraminate cytidylyltransferase activity 8750 1 0 0 0 1 NAD(P)+ transhydrogenase (AB-specific) activity 8746 1 0 0 0 1 NAD(P)+ transhydrogenase activity 8705 1 0 0 0 1 5-methyltetrahydrofolate-homocysteine S-methyltransferase activity 15898 1 0 0 0 1 amiloride transport 15893 2 0 0 0 1 drug transport 15888 2 0 0 0 1 thiamin transport 15884 1 0 0 0 1 folate transport 15875 2 0 0 0 1 vitamin/cofactor transport 15872 2 0 0 0 1 dopamine transport 3896 1 0 0 0 1 DNA primase activity 3895 4 0 0 0 1 gamma DNA-directed DNA polymerase activity 3894 3 0 0 0 1 zeta DNA polymerase activity 3893 2 0 0 0 1 epsilon DNA polymerase activity 3891 4 0 0 0 1 delta DNA polymerase activity 3890 2 0 0 0 1 beta DNA polymerase activity 15864 1 0 0 0 1 pyrimidine nucleoside transport 15860 2 0 0 0 1 purine nucleoside transport 3889 2 0 0 0 1 alpha DNA polymerase activity 3887 16 0 0 0 1 DNA-directed DNA polymerase activity 3886 2 0 0 0 1 DNA (cytosine-5-)-methyltransferase activity 3883 2 0 0 0 1 CTP synthase activity 3882 1 0 0 0 1 CDP-diacylglycerol-serine O-phosphatidyltransferase activity 3881 1 0 0 0 1 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity 3880 2 0 0 0 1 C-terminal protein carboxyl methyltransferase activity 15858 4 0 0 0 1 nucleoside transport 3879 1 0 0 0 1 ATP phosphoribosyltransferase activity 3878 1 0 0 0 1 ATP citrate synthase activity 3876 4 0 0 0 1 AMP deaminase activity 3875 1 0 0 0 1 ADP-ribosylarginine hydrolase activity 3873 2 0 0 0 1 6-phosphofructo-2-kinase activity 3870 2 0 0 0 1 5-aminolevulinate synthase activity 15846 1 0 0 0 1 polyamine transport 15840 3 0 0 0 1 urea transport 3868 1 0 0 0 1 4-hydroxyphenylpyruvate dioxygenase activity 3865 2 0 0 0 1 3-oxo-5-alpha-steroid 4-dehydrogenase activity 3863 2 0 0 0 1 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity 3860 1 0 0 0 1 3-hydroxyisobutyryl-CoA hydrolase activity 15833 6 0 0 0 1 peptide transport 3858 1 0 0 0 1 3-hydroxybutyrate dehydrogenase activity 3854 2 0 0 0 1 3-beta-hydroxy-delta(5)-steroid dehydrogenase activity 3851 1 0 0 0 1 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 15824 1 0 0 0 1 proline transport 3845 2 0 0 0 1 11-beta-hydroxysteroid dehydrogenase activity 3844 1 0 0 0 1 "1,4-alpha-glucan branching enzyme activity" 3840 3 0 0 0 1 gamma-glutamyl transferase activity 15817 2 0 0 0 1 histidine transport 3837 1 0 0 0 1 beta-ureidopropionase activity 3836 2 0 0 0 1 "beta-galactoside alpha-2,3-sialyltransferase activity" 3834 2 0 0 0 1 "beta-carotene 15,15'-dioxygenase activity" 3832 1 0 0 0 1 beta-alanyl-dopamine hydrolase activity 3831 3 0 0 0 1 "beta-N-acetylglucosaminyl-glycopeptide beta-1,4-galactosyltransferase activity" 3830 1 0 0 0 1 "beta-1,4-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" 15807 4 0 0 0 1 L-amino acid transport 15806 1 0 0 0 1 S-methylmethionine transport 15804 2 0 0 0 1 neutral amino acid transport 15802 3 0 0 0 1 basic amino acid transport 3829 2 0 0 0 1 "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity" 3828 5 0 0 0 1 "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity" 3826 1 0 0 0 1 alpha-ketoacid dehydrogenase activity 3825 1 0 0 0 1 "alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity" 3813 1 0 0 0 1 classical-complement pathway C3/C5 convertase activity 3809 3 0 0 0 1 thrombin activity 3808 1 0 0 0 1 protein C (activated) activity 3807 1 0 0 0 1 plasma kallikrein activity 3803 1 0 0 0 1 blood coagulation factor IX activity 3802 1 0 0 0 1 blood coagulation factor VII activity 3801 16 0 0 0 1 blood coagulation factor activity 46935 1 0 0 0 1 phosphatidylinositol 3-kinase regulator activity 46923 2 0 0 0 1 ER retention sequence binding 46915 6 0 0 1 1 transition metal ion transporter activity 46912 1 0 0 0 1 "transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer" 8656 2 0 0 0 1 caspase activator activity 8653 1 0 0 0 1 lipopolysaccharide metabolism 8651 2 0 0 0 1 actin polymerizing activity 8648 1 0 0 0 1 tachykinin 8645 7 0 0 0 1 hexose transport 8643 17 0 0 3 1 carbohydrate transport 8642 2 0 0 0 1 ubiquitin-like activating enzyme activity 8641 2 0 0 0 1 small protein activating enzyme activity 8637 4 0 0 0 1 apoptotic mitochondrial changes 8630 2 0 0 0 1 "DNA damage response, signal transduction resulting in induction of apoptosis" 8628 1 0 0 0 1 induction of apoptosis by hormones 8624 5 0 0 1 1 induction of apoptosis by extracellular signals 8611 1 0 0 0 1 ether lipid biosynthesis 8608 1 0 0 0 1 microtubule/kinetochore interaction 8606 1 0 0 0 1 "phosphorylase kinase, catalyst activity" 8604 1 0 0 0 1 "protein kinase CK2, catalyst activity" 8602 1 0 0 0 1 "cAMP-dependent protein kinase, catalyst activity" 3799 1 0 0 0 1 antifungal peptide activity 3794 3 0 0 0 1 acute-phase response protein activity 3792 1 0 0 0 1 regulation of actin thin filament length activity 3790 1 0 0 0 1 actin modulating activity 3786 2 0 0 0 1 actin lateral binding 3781 4 0 0 0 1 actin bundling activity 3780 2 0 0 0 1 actin cross-linking activity 15758 7 0 0 0 1 glucose transport 15757 1 0 0 0 1 galactose transport 15755 1 0 0 0 1 fructose transport 3776 1 0 0 0 1 muscle motor activity 15749 7 0 0 0 1 monosaccharide transport 3767 4 0 0 0 1 co-chaperone activity 3763 1 0 0 0 1 chaperonin ATPase activity 3762 1 0 0 0 1 histone-specific chaperone activity 15732 1 0 0 0 1 prostaglandin transport 15724 1 0 0 0 1 formate transport 15722 1 0 0 0 1 canalicular bile acid transport 15721 1 0 0 0 1 bile acid transport 3747 1 0 0 0 1 translation release factor activity 15718 3 0 0 0 1 monocarboxylic acid transport 15711 18 0 0 0 1 organic anion transport 15701 3 0 0 0 1 bicarbonate transport 15700 1 0 0 0 1 arsenite transport 3721 1 0 0 0 1 telomeric template RNA reverse transcriptase activity 3720 1 0 0 0 1 telomerase activity 3719 1 0 0 0 1 "transcription factor binding, cytoplasmic sequestering" 3712 59 0 0 10 1 transcription cofactor activity 3711 6 0 0 0 1 transcriptional elongation regulator activity 3709 1 0 0 0 1 RNA polymerase III transcription factor activity 3708 3 0 0 0 1 retinoic acid receptor activity 3705 7 0 0 1 1 "RNA polymerase II transcription factor activity, enhancer binding" 3704 7 0 0 0 1 specific RNA polymerase II transcription factor activity 3701 1 0 0 0 1 RNA polymerase I transcription factor activity 46851 1 0 0 0 1 negative regulation of bone remodeling 46850 2 0 0 0 1 regulation of bone remodeling 46845 2 0 0 0 1 branch cell fate determination (sensu Insecta) 8599 2 0 0 0 1 "protein phosphatase type 1, regulator activity" 8594 7 0 0 1 1 photoreceptor cell morphogenesis (sensu Drosophila) 8593 2 0 0 0 1 regulation of N receptor signaling pathway 46824 1 0 0 0 1 positive regulation of nucleocytoplasmic transport 46821 3 0 0 0 1 extrachromosomal DNA 8586 2 0 0 0 1 wing vein morphogenesis 8585 5 0 0 0 1 female gonad development 8584 1 0 0 0 1 male gonad development 8582 2 0 0 0 1 regulation of synaptic growth at neuromuscular junction 8580 3 0 0 0 1 cytoskeletal regulator activity 8574 1 0 0 0 1 plus-end-directed kinesin ATPase activity 8570 1 0 0 0 1 myosin ATPase activity 8569 2 0 0 0 1 minus-end-directed kinesin ATPase activity 8546 1 0 0 0 1 microtubule/chromatin interaction 8544 6 0 0 1 1 epidermal differentiation 8536 7 0 0 0 1 RAN protein binding 8534 1 0 0 0 1 purine-specific oxidized base lesion DNA N-glycosylase activity 8533 10 0 0 0 1 astacin activity 8521 1 0 0 0 1 acetyl-CoA transporter activity 8519 3 0 0 0 1 ammonium transporter activity 8518 2 0 0 0 1 reduced folate carrier activity 8517 4 0 0 0 1 folate transporter activity 8516 1 0 0 0 1 hexose uniporter activity 8514 19 0 0 0 1 organic anion transporter activity 8513 11 0 0 0 1 organic cation porter activity 8510 1 0 0 0 1 sodium:bicarbonate symporter activity 8509 32 0 0 0 1 anion transporter activity 8508 3 0 0 0 1 bile acid:sodium symporter activity 8507 1 0 0 0 1 sodium:iodide symporter activity 8504 1 0 0 0 1 monoamine transporter activity 8502 3 0 0 0 1 melatonin receptor activity 15695 1 0 0 0 1 organic cation transport 3690 8 0 0 0 1 double-stranded DNA binding 3689 5 0 0 0 1 DNA clamp loader activity 3688 1 0 0 0 1 DNA replication origin binding 3680 1 0 0 0 1 AT DNA binding 3678 12 0 0 2 1 DNA helicase activity 3673 6576 0 0 1184 1 Gene_Ontology 15645 5 0 0 1 1 fatty-acid ligase activity 46786 1 0 0 0 1 viral replication complex formation and maintenance 8499 4 0 0 0 1 "UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" 8495 1 0 0 0 1 protoheme IX farnesyltransferase activity 8494 1 0 0 0 1 translation activator activity 8488 2 0 0 0 1 gamma-glutamyl carboxylase activity 8487 1 0 0 0 1 prenyl-dependent CAAX protease activity 8484 8 0 0 0 1 sulfuric ester hydrolase activity 8483 21 0 0 3 1 transaminase activity 8481 1 0 0 0 1 sphinganine kinase activity 46709 1 0 0 0 1 IDP catabolism 46707 1 0 0 0 1 IDP metabolism 8470 1 0 0 0 1 isovaleryl-CoA dehydrogenase activity 8466 1 0 0 0 1 glycogenin glucosyltransferase activity 8464 2 0 0 0 1 gamma-glutamyl hydrolase activity 8462 1 0 0 0 1 endopeptidase Clp activity 8458 1 0 0 0 1 carnitine O-octanoyltransferase activity 8455 1 0 0 0 1 "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" 8453 2 0 0 0 1 alanine-glyoxylate aminotransferase activity 8450 1 0 0 0 1 O-sialoglycoprotein endopeptidase activity 8449 1 0 0 0 1 N-acetylglucosamine-6-sulfatase activity 8444 1 0 0 0 1 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity 8441 1 0 0 0 1 "3'(2'),5'-bisphosphate nucleotidase activity" 8437 1 0 0 0 1 thyrotropin-releasing hormone activity 8434 1 0 0 0 1 vitamin D3 receptor activity 8431 1 0 0 0 1 tocopherol binding 8423 1 0 0 0 1 bleomycin hydrolase activity 8419 1 0 0 0 1 RNA lariat debranching enzyme activity 8413 1 0 0 0 1 "7,8-dihydro-8-oxoguanine-triphosphatase activity" 8410 2 0 0 0 1 CoA-transferase activity 8409 3 0 0 0 1 5'-3' exonuclease activity 8408 12 0 0 0 1 3'-5' exonuclease activity 8407 1 0 0 0 1 bristle morphogenesis 8406 7 0 0 0 1 gonad development 15559 1 0 0 0 1 multidrug efflux pump activity 46698 5 0 0 1 1 metamorphosis (sensu Insecta) 46685 1 0 0 0 1 response to arsenate 46683 1 0 0 0 1 response to organophosphorous 46681 1 0 0 0 1 response to carbamate 46677 1 0 0 0 1 response to antibiotic 46663 1 0 0 0 1 leading edge cell differentiation 46653 1 0 0 0 1 tetrahydrofolate metabolism 46652 1 0 0 0 1 thymocyte differentiation 46651 3 0 0 0 1 lymphocyte proliferation 46650 3 0 0 0 1 lymphocyte differentiation 46649 12 0 0 0 1 lymphocyte activation 8395 4 0 0 0 1 steroid hydroxylase activity 46627 1 0 0 0 1 negative regulation of insulin receptor signaling pathway 46626 1 0 0 0 1 regulation of insulin receptor signaling pathway 46625 1 0 0 0 1 sphingolipid binding 46622 1 0 0 0 1 positive regulation of organ size 46621 1 0 0 0 1 negative regulation of organ size 8387 1 0 0 0 1 steroid 7-alpha-hydroxylase activity 8384 1 0 0 0 1 IkappaB kinase activity 8383 1 0 0 0 1 manganese superoxide dismutase activity 8378 15 0 0 0 1 galactosyltransferase activity 8375 8 0 0 1 1 acetylglucosaminyltransferase activity 8355 3 0 0 0 1 olfactory learning 8354 2 0 0 0 1 germ-cell migration 8353 1 0 0 0 1 [RNA-polymerase]-subunit kinase activity 8349 1 0 0 0 1 MAP kinase kinase kinase kinase activity 8347 1 0 0 0 1 glia cell migration 8345 1 0 0 0 1 larval locomotory behavior 8344 6 0 0 1 1 adult locomotory behavior 8342 1 0 0 0 1 larval feeding behavior (sensu Insecta) 8336 1 0 0 0 1 "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity" 8334 1 0 0 0 1 histone mRNA metabolism 8332 2 0 0 0 1 low voltage-gated calcium channel activity 8331 4 0 0 0 1 high voltage-gated calcium channel activity 8327 1 0 0 0 1 methyl-CpG binding 8321 1 0 0 0 1 Ral guanyl-nucleotide exchange factor activity 8315 2 0 0 0 1 meiotic G2/MI transition 8314 1 0 0 0 1 gurken receptor signaling pathway 8313 1 0 0 0 1 gurken receptor activity 8308 5 0 0 1 1 voltage-dependent ion-selective channel activity 8307 5 0 0 0 1 structural constituent of muscle 8306 1 0 0 0 1 associative learning 8301 4 0 0 0 1 DNA bending activity 8300 1 0 0 0 1 isoprenoid catabolism 15499 1 0 0 0 1 formate transporter activity 15491 8 0 0 0 1 cation:cation antiporter activity 15467 4 0 0 0 1 G-protein activated inward rectifier potassium channel activity 15464 1 0 0 0 1 acetylcholine receptor activity 15457 4 0 0 0 1 auxiliary transport protein activity 46590 2 0 0 0 1 leg morphogenesis 46579 1 0 0 0 1 positive regulation of RAS protein signal transduction 46578 1 0 0 0 1 regulation of RAS protein signal transduction 46552 1 0 0 0 1 photoreceptor cell fate commitment 46530 10 0 0 1 1 photoreceptor cell differentiation 8295 2 0 0 0 1 spermidine biosynthesis 8294 2 0 0 0 1 calcium/calmodulin-responsive adenylate cyclase activity 8291 1 0 0 0 1 acetylcholine metabolism 8290 5 0 0 1 1 actin capping protein complex 8281 2 0 0 0 1 sulfonylurea receptor activity 8277 4 0 0 0 1 regulation of G-protein coupled receptor protein signaling pathway 8276 8 0 0 0 1 protein methyltransferase activity 8273 2 0 0 0 1 "calcium, potassium:sodium antiporter activity" 8272 7 0 0 0 1 sulfate transport 8271 5 0 0 0 1 sulfate porter activity 46504 1 0 0 0 1 glycerol ether biosynthesis 46503 1 0 0 0 1 glycerolipid catabolism 8269 1 0 0 0 1 JAK pathway signal transduction adaptor activity 8268 1 0 0 0 1 receptor signaling protein tyrosine kinase signaling protein activity 8265 1 0 0 0 1 Mo-molybdopterin cofactor sulfurase activity 8262 1 0 0 0 1 importin-alpha export receptor activity 8260 2 0 0 0 1 3-oxoacid CoA-transferase activity 8253 2 0 0 0 1 5'-nucleotidase activity 8252 3 0 0 0 1 nucleotidase activity 8251 1 0 0 0 1 tRNA specific adenosine deaminase activity 8247 1 0 0 0 1 2-acetyl-1-alkylglycerophosphocholine esterase complex 8246 7 0 0 1 1 electron transfer flavoprotein 8243 4 0 0 0 1 plasminogen activator activity 8242 2 0 0 0 1 omega peptidase activity 8241 2 0 0 0 1 peptidyl-dipeptidase activity 8240 1 0 0 0 1 tripeptidyl-peptidase activity 8227 29 0 0 0 1 amine receptor activity 8225 1 0 0 0 1 Gram-negative antibacterial peptide activity 8220 4 0 0 0 1 necrosis 8217 15 0 0 0 1 regulation of blood pressure 8216 2 0 0 0 1 spermidine metabolism 8213 6 0 0 0 1 protein amino acid alkylation 8212 3 0 0 0 1 mineralocorticoid metabolism 8207 11 0 0 0 1 C21-steroid hormone metabolism 8206 2 0 0 0 1 bile acid metabolism 8204 1 0 0 0 1 ergosterol metabolism 15390 1 0 0 0 1 purine-specific nucleoside:sodium symporter activity 15389 1 0 0 0 1 pyrimidine- and adenine-specific:sodium symporter activity 15385 3 0 0 0 1 sodium:hydrogen antiporter activity 15380 9 0 0 0 1 anion exchanger activity 15379 1 0 0 0 1 potassium:chloride symporter activity 15377 7 0 0 1 1 cation:chloride symporter activity 15373 1 0 0 0 1 monovalent anion:sodium symporter activity 15368 5 0 0 0 1 calcium:cation antiporter activity 15362 1 0 0 0 1 high affinity sodium:dicarboxylate symporter activity 15355 4 0 0 0 1 monocarboxylate porter activity 15354 6 0 0 0 1 polyspecific organic cation transporter activity 15334 1 0 0 0 1 high affinity oligopeptide transporter activity 15321 2 0 0 0 1 sodium-dependent phosphate transporter activity 15302 2 0 0 0 1 uncoupling protein activity 15301 9 0 0 0 1 anion:anion antiporter activity 15300 2 0 0 0 1 solute:solute antiporter activity 46488 4 0 0 0 1 phosphatidylinositol metabolism 46486 6 0 0 0 1 glycerolipid metabolism 46485 1 0 0 0 1 ether lipid metabolism 46483 45 0 0 8 1 heterocycle metabolism 46470 2 0 0 0 1 phosphatidylcholine metabolism 46464 1 0 0 0 1 acylglycerol catabolism 46463 1 0 0 0 1 acylglycerol biosynthesis 46461 1 0 0 0 1 neutral lipid catabolism 46460 1 0 0 0 1 neutral lipid biosynthesis 46457 5 0 0 0 1 prostanoid biosynthesis 46439 2 0 0 0 1 L-cysteine metabolism 8195 2 0 0 0 1 phosphatidate phosphatase activity 8192 1 0 0 0 1 RNA guanylyltransferase activity 46425 2 0 0 0 1 regulation of JAK-STAT cascade 8188 30 0 0 0 1 neuropeptide receptor activity 8187 1 0 0 0 1 poly-pyrimidine tract binding 8184 1 0 0 0 1 glycogen phosphorylase activity 8180 2 0 0 0 1 signalosome complex 8174 1 0 0 0 1 mRNA methyltransferase activity 8172 6 0 0 0 1 S-methyltransferase activity 8159 1 0 0 0 1 positive transcription elongation factor activity 8158 4 0 0 0 1 patched receptor activity 8157 1 0 0 0 1 protein phosphatase 1 binding 8156 1 0 0 0 1 negative regulation of DNA replication 8139 1 0 0 0 1 nuclear localization sequence binding 8133 3 0 0 0 1 collagenase activity 8132 1 0 0 0 1 pancreatic elastase activity 8131 4 0 0 0 1 amine oxidase activity 8130 1 0 0 0 1 neutrophil collagenase activity 8127 1 0 0 0 1 "quercetin 2,3-dioxygenase activity" 8124 1 0 0 0 1 4a-hydroxytetrahydrobiopterin dehydratase activity 8123 1 0 0 0 1 cholesterol 7-alpha-monooxygenase activity 8122 2 0 0 0 1 amine oxidase (copper-containing) activity 8119 1 0 0 0 1 thiopurine S-methyltransferase activity 8116 1 0 0 0 1 prostaglandin-I synthase activity 8115 1 0 0 0 1 sarcosine oxidase activity 8113 1 0 0 0 1 protein-methionine-S-oxide reductase activity 8112 1 0 0 0 1 nicotinamide N-methyltransferase activity 8111 1 0 0 0 1 alpha-methylacyl-CoA racemase activity 8109 1 0 0 0 1 "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity" 8108 1 0 0 0 1 UDP-glucose-hexose-1-phosphate uridylyltransferase activity 8103 1 0 0 0 1 oocyte microtubule cytoskeleton polarization 15299 2 0 0 0 1 solute:hydrogen antiporter activity 15298 2 0 0 0 1 solute:cation antiporter activity 15297 20 0 0 0 1 antiporter activity 15296 7 0 0 1 1 anion:cation symporter activity 15295 1 0 0 0 1 solute:hydrogen symporter activity 15292 1 0 0 0 1 uniporter activity 15288 13 0 0 2 1 porin activity 15285 11 0 0 0 1 connexon channel activity 15284 1 0 0 0 1 fructose uniporter activity 15279 2 0 0 0 1 store-operated calcium channel activity 15278 1 0 0 0 1 calcium-release channel activity 15277 2 0 0 0 1 kainate selective glutamate receptor activity 15272 1 0 0 0 1 ATP-activated inward rectifier potassium channel activity 15270 2 0 0 0 1 dihydropyridine-sensitive calcium channel activity 15269 6 0 0 0 1 calcium-activated potassium channel activity 15259 15 0 0 0 1 glutamate channel activity 15256 15 0 0 0 1 monocarboxylate channel activity 15250 9 0 0 1 1 water channel activity 15248 2 0 0 0 1 sterol transporter activity 15247 1 0 0 0 1 aminophospholipid transporter activity 15239 1 0 0 0 1 multidrug transporter activity 15238 1 0 0 0 1 drug transporter activity 15234 2 0 0 0 1 thiamin transporter activity 15232 1 0 0 0 1 heme transporter activity 15223 7 0 0 0 1 vitamin/cofactor transporter activity 15221 1 0 0 0 1 lipopolysaccharide transporter activity 15211 1 0 0 0 1 purine nucleoside transporter activity 15205 1 0 0 0 1 nucleobase transporter activity 15204 2 0 0 0 1 urea transporter activity 46395 2 0 0 0 1 carboxylic acid catabolism 46380 1 0 0 0 1 N-acetylneuraminate biosynthesis 46351 1 0 0 0 1 disaccharide biosynthesis 46340 1 0 0 0 1 diacylglycerol catabolism 46339 2 0 0 0 1 diacylglycerol metabolism 46337 1 0 0 0 1 phosphatidylethanolamine metabolism 46335 1 0 0 0 1 ethanolamine biosynthesis 46332 1 0 0 0 1 SMAD binding 8099 4 0 0 0 1 synaptic vesicle endocytosis 8095 1 0 0 0 1 "inositol-1,4,5-triphosphate receptor activity" 8093 1 0 0 0 1 cytoskeletal adaptor activity 46329 1 0 0 0 1 negative regulation of JNK cascade 46328 1 0 0 0 1 regulation of JNK cascade 8079 1 0 0 0 1 translation termination factor activity 8077 1 0 0 0 1 Hsp70/Hsp90 organizing protein activity 8076 17 0 0 0 1 voltage-gated potassium channel complex 8075 1 0 0 0 1 receptor guanylate cyclase activity 8074 1 0 0 0 1 "guanylate cyclase complex, soluble" 8071 1 0 0 0 1 "maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded (sensu Insecta)" 8069 2 0 0 0 1 "dorsal/ventral axis determination, follicular epithelium (sensu Insecta)" 8065 1 0 0 0 1 establishment of blood/nerve barrier 8063 5 0 0 0 1 Tl receptor signaling pathway 8062 2 0 0 0 1 eclosion rhythm 8061 1 0 0 0 1 chitin binding 8060 1 0 0 0 1 ARF GTPase activator activity 8055 1 0 0 0 1 ocellus pigment biosynthesis 8052 1 0 0 0 1 sensory organ determination 8049 1 0 0 0 1 male courtship behavior 8048 1 0 0 0 1 calcium sensitive guanylate cyclase activator activity 8046 7 0 0 0 1 axon guidance receptor activity 8045 3 0 0 0 1 motor axon guidance 8042 2 0 0 0 1 iron-sulfur electron transfer carrier 8035 1 0 0 0 1 high-density lipoprotein binding 8034 5 0 0 1 1 lipoprotein binding